Neoplasms

Urinary Tract, Sexual Organs, and Pregnancy Conditions

All Conditions

Urinary Bladder Neoplasms

Urologic Neoplasms

Urogenital Neoplasms

Urogenital Diseases

Female Urogenital Diseases

Pregnancy Complications

Female Urogenital Diseases and Pregnancy Complications

Urinary Bladder Diseases

Urologic Diseases

Male Urogenital Diseases

Micronutrients

Anti-Infective Agents

All Drugs and Chemicals

Antineoplastic Agents

Iodine

Ethiodized Oil

Cadexomer iodine

1-3 drops of Lipiodol Ultra Fluid (iodine 38%W/W) will be injected into the submucosa on 4 locations around the bladder tumour. The procedure is done once during a planned cystoscopy approximately a week before the planning CT.

Lipiodol demarcation of the bladder tumour

Jimmi Søndergaard, M.D

Rationale: Bladder tumours are often not visible on X-ray based image-modalities during planning and treatment of Radiotherapy.

Purpose: To determine if a single contrast (Lipiodol) demarcation of the bladder tumour before treatment is feasible and visible on multiple X-ray based image-modalities during Radiotherapy.

To exploit the potential of modern Radiotherapy (RT), it is important to localize and follow the target precisely during treatment. Since the bladder tumour can usually not be identified on conventional CT-scan, a fiducial or contrast marking system is warranted.

The iodized oil, Lipiodol is a well-known contrast media used mainly for lymphography and Hysterosalpingography. Local Lipiodol demarcation has been used for localisation of tumours in the lung, prostate and seminal vesicles visualised on Computed Tomography (CT) and fluoroscopy.

Purpose: To evaluate the feasibility of tumour demarcation using the contrast agent Lipiodol in adaptive Image-guided RT of bladder cancer. Visibility on CT, Cone-Beam CT, MRI and on-board imaging will be evaluated.

Pilot Studie of Lipiodol Demarcation of the Tumour in Bladder Cancer

Lipiodol Demarcation of the Bladder Tumour in Adaptive Image-guided Radiotherapy: A Pilot Study. (Danish: Lipiodol Til Markering af blæretumoren i Forbindelse Med Adaptiv Billedvejledt strålebehandling: Et Pilotstudie.)

Aarhus University Hospital

University of Aarhus

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Pilot Studie of Lipiodol Demarcation of the Tumour in Bladder Cancer	NCT00609843	Bladder Cancer	Lipiodol demarc...	18 Years -	University of Aarhus
Pilot Studie of Lipiodol Demarcation of the Tumour in Bladder Cancer	NCT00609843	Bladder Cancer	Lipiodol demarc...	18 Years -	University of Aarhus

Spots Global Cancer Trial Database for lipiodol demarcation of the bladder tumour