Symptoms and General Pathology

All Conditions

Neoplasms

Urinary Tract, Sexual Organs, and Pregnancy Conditions

Gland and Hormone Related Diseases

Syndrome

Polycystic Ovary Syndrome

Cysts

Ovarian Cysts

Ovarian Diseases

Adnexal Diseases

Genital Diseases, Female

Genital Diseases

Urogenital Diseases

Female Urogenital Diseases

Pregnancy Complications

Female Urogenital Diseases and Pregnancy Complications

Gonadal Disorders

Endocrine System Diseases

Hematinics

All Drugs and Chemicals

Herbal and Botanical

Liver Extracts

Olive

20/50 fish oil, 1000mg capsules, Ocean Nutrition 2050,4g/day.

1000mg capsules, 4 capsules/day for 8 weeks

Ocean Nutrition 2050

Olive oil capsules, 4 per day for 8 weeks

Olive oil capsules

Andrea J Cussons, MBBS

We hypothesise that fish oils will have a beneficial effect on cardiometabolic parameters in women with PCOS. The purpose of this study therefore is to examine the effects of fish oils on blood pressure, heart rate variability and liver fat content in obese women with the polycystic ovary syndrome.

The prevalence of abnormalities of blood pressure (ABP), variability of heart rate (HRV) and liver fat content is increased in women with the polycystic ovary syndrome (PCOS). We hypothesise that fish oils will have a beneficial effect on these endpoints and other cardiometabolic parameters such as cholesterol and liver function in women with PCOS. This crossover study of 40 obese women with PCOS will therefore examine the effects of fish oils on the above parameters compared with placebo (olive oil). Subjects with PCOS who have participated in previous studies with this research group will be approached for recruitment, as will eligible subjects within the endocrine clinics of the chief and co-investigators.

The Effects of Fish Oils on Blood Pressure, Heart Rate Variability and Liver Fat in the Polycystic Ovary Syndrome

A Clinical Trial to Measure the Effect of DHA-enriched Fish Oils on Blood Pressure, Heart Rate Variability and Liver Fat Content in the Polycystic Ovary Syndrome

Royal Perth Hospital

Keogh Institute for Medical Research

Dr Andrea Cussons

Nutritional and Metabolic Diseases

Heart and Blood Diseases

Glucose Intolerance

Metabolic Diseases

Insulin Resistance

Glucose Metabolism Disorders

Cardiac Complexes, Premature

Hyperglycemia

Hypoglycemic Agents

Insulin

Insulin, Globin Zinc

For the assessment of glucose metabolism, including beta-cell function and insulin sensitivity an 75g-OGTT was conducted.

Oral glucose tolerance test (OGTT)

The amount of ectopic lipids in the liver, heart and the skeletal muscle was measured using 1H-magnetic resonance spectroscopy.

1H-magnetic resonance spectroscopy

Alexandra Kautzky-Willer, Univ.Prof.Dr.

In the present study glucose metabolism and ectopic lipids in the liver, heart and muscle were investigated in women with the polycystic ovary syndrome (PCOS) and in healthy control subjects.

In detail an oral glucose tolerance test (OGTT) was conducted in women with the PCOS defined by the Rotterdam and the NIH-criteria, as well as in healthy control subjects. In addition 1H-magnetic resonance spectroscopy and Imaging was used for the assessment of the ectopic lipid content in the liver, heart and skeletal muscle. The aim of the present study was to compare the glucose metabolism and the ectopic lipid conent in the liver, heart and muscle between women with the PCOS defined by the NIH-criteria, Rotterdam-criteria and healthy control subjects.

Glucose Metabolism in Different PCOS Phenotypes

Associatons of PCOS Phenotypes With Ectopic Lipids, Adipocytokines and Parameters of Insulin Resistance

In the present study the Glucose metabolism in PCOS women and control subjects was assessed with an OGTT. Therefore the dynamic levels of glucose, insulin and C-peptide were assessed during an extended OGTT for the calculation of Insulin resistance and beta-cell function. In addition an 1H-magnetic resonance spectroscopy was done for the assessment of the ectopic lipid content in the liver, heart and the skeletal muscle.

Medical University of Vienna

Univ.Prof.Dr.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
The Effects of Fish Oils on Blood Pressure, Heart Rate Variability and Liver Fat in the Polycystic Ovary Syndrome	NCT00620529	Polycystic Ovar...	Ocean Nutrition... Olive oil capsu...	18 Years - 50 Years	Keogh Institute for Medical Research
Glucose Metabolism in Different PCOS Phenotypes	NCT03204461	Polycystic Ovar... Glucose Intoler... Liver Fat Glucose Metabol...	Oral glucose to... 1H-magnetic res...	20 Years - 40 Years	Medical University of Vienna
Glucose Metabolism in Different PCOS Phenotypes	NCT03204461	Polycystic Ovar... Glucose Intoler... Liver Fat Glucose Metabol...	Oral glucose to... 1H-magnetic res...	20 Years - 40 Years	Medical University of Vienna
The Effects of Fish Oils on Blood Pressure, Heart Rate Variability and Liver Fat in the Polycystic Ovary Syndrome	NCT00620529	Polycystic Ovar...	Ocean Nutrition... Olive oil capsu...	18 Years - 50 Years	Keogh Institute for Medical Research
The Effects of Fish Oils on Blood Pressure, Heart Rate Variability and Liver Fat in the Polycystic Ovary Syndrome	NCT00620529	Polycystic Ovar...	Ocean Nutrition... Olive oil capsu...	18 Years - 50 Years	Keogh Institute for Medical Research

Spots Global Cancer Trial Database for liver fat

Every month we try and update this database with for liver fat cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for liver fat

Every month we try and update this database with for liver fat cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for liver fat cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.