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Spots Global Cancer Trial Database for locally advanced esophageal squamous cell carcinoma

Every month we try and update this database with for locally advanced esophageal squamous cell carcinoma cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.

Study titleNCT IDConditionsInterventionsEligibilityOrganizationLink
AK104 Alone or in Combination With Chemotherapy in the First-line Treatment of ESCCNCT05522894
Unresectable Es...
Locally Advance...
Metastatic Esop...
AK104
Cisplatin
Paclitaxel
18 Years - 75 YearsChineseAMS
Efficacy and Safety of Concurrent PD-1 Inhibitor and Radiotherapy With Immunonutrition for Esophageal Squamous Cell CarcinomaNCT06342167
Locally Advance...
Sintilimab
Radiotherapy
Concurrent Chem...
Immunonutrition
Radiotherapy
Programmed Cell...
Immunonutrition...
18 Years - 80 YearsCancer Institute and Hospital, Chinese Academy of Medical Sciences
Combination of Tislelizumab and Chemoradiotherapy in Esophageal Cancer (EC-CRT-002)NCT05520619
Esophageal Squa...
Locally Advance...
Paclitaxel, Cis...
tislelizumab
Radiotherapy
18 Years - 70 YearsSun Yat-sen University
Consolidation of Toripalimab After Chemoradiotherapy in Elderly Esophageal Cancer (EC-CRT-007)NCT06187597
Locally Advance...
S-1
Toripalimab
Intensity-modul...
70 Years - 85 YearsSun Yat-sen University
A Feasibility Trial of Nivolumab With Neoadjuvant CF or DCF Therapy for Locally Advanced Esophageal CarcinomaNCT03914443
Locally Advance...
Nivolumab
5-FU
CDDP
DTX
20 Years - 75 YearsNational Cancer Center, Japan
Efficacy and Safety of Concurrent PD-1 Inhibitor and Radiotherapy With Immunonutrition for Esophageal Squamous Cell CarcinomaNCT06342167
Locally Advance...
Sintilimab
Radiotherapy
Concurrent Chem...
Immunonutrition
Radiotherapy
Programmed Cell...
Immunonutrition...
18 Years - 80 YearsCancer Institute and Hospital, Chinese Academy of Medical Sciences
Sintilimab Injection Combined With Concurrent CCRT in Locally Advanced Esophageal Squamous Cell CarcinomaNCT04602013
Locally Advance...
Sintilimab
Chemotherapy
Radiation Thera...
18 Years - 75 YearsSichuan Cancer Hospital and Research Institute
Immunotherapy With CCRT Followed by Surgery for Locally Advanced ESCC PatientsNCT05743504
Locally Advance...
Tiragolumab
20 Years - National Taiwan University Hospital
A Clinical Study on the Efficacy and Safety of Paclitaxel Polymer Micelles and Cisplatin Combined With Cadonilimab as a Neoadjuvant Therapy for Locally Advanced Esophageal Squamous Cell CarcinomaNCT06356688
Locally Advance...
Neoadjuvant The...
paclitaxel poly...
18 Years - 75 YearsThe First Affiliated Hospital with Nanjing Medical University
Consolidation of Toripalimab After Chemoradiotherapy in Elderly Esophageal Cancer (EC-CRT-007)NCT06187597
Locally Advance...
S-1
Toripalimab
Intensity-modul...
70 Years - 85 YearsSun Yat-sen University
Immunotherapy With CCRT Followed by Surgery for Locally Advanced ESCC PatientsNCT05743504
Locally Advance...
Tiragolumab
20 Years - National Taiwan University Hospital
Immunotherapy With CCRT Followed by Surgery for Locally Advanced ESCC PatientsNCT05743504
Locally Advance...
Tiragolumab
20 Years - National Taiwan University Hospital
A Feasibility Trial of Nivolumab With Neoadjuvant CF or DCF Therapy for Locally Advanced Esophageal CarcinomaNCT03914443
Locally Advance...
Nivolumab
5-FU
CDDP
DTX
20 Years - 75 YearsNational Cancer Center, Japan
Exploring the Safety and Effectiveness of Toripalimab Combined With Neoadjuvant Radiotherapy and Chemotherapy in the Locally Advanced Esophageal Squamous Cell CarcinomaNCT04888403
Locally Advance...
Toripalimab+Ned...
18 Years - 70 YearsThe First Affiliated Hospital of Zhengzhou University
Efficacy and Safety of Concurrent PD-1 Inhibitor and Radiotherapy With Immunonutrition for Esophageal Squamous Cell CarcinomaNCT06342167
Locally Advance...
Sintilimab
Radiotherapy
Concurrent Chem...
Immunonutrition
Radiotherapy
Programmed Cell...
Immunonutrition...
18 Years - 80 YearsCancer Institute and Hospital, Chinese Academy of Medical Sciences
The Phase II Trial of SHR-1210 Combined With Preoperative Chemotherapy or Apatinib for Locally Advanced ESCCNCT03917966
Locally Advance...
SHR-1210+doceta...
SHR-1210+Apatin...
18 Years - 80 YearsThe First Affiliated Hospital of Zhengzhou University
Neoadjuvant Cadonilimab Combined With Anlotinib in Locally Advanced Resectable Esophageal Squamous Cell CarcinomaNCT06426797
Locally Advance...
Cadonilimab plu...
18 Years - Peking University People's Hospital
Exploring the Safety and Effectiveness of Toripalimab Combined With Neoadjuvant Radiotherapy and Chemotherapy in the Locally Advanced Esophageal Squamous Cell CarcinomaNCT04888403
Locally Advance...
Toripalimab+Ned...
18 Years - 70 YearsThe First Affiliated Hospital of Zhengzhou University
A Feasibility Trial of Nivolumab With Neoadjuvant CF or DCF Therapy for Locally Advanced Esophageal CarcinomaNCT03914443
Locally Advance...
Nivolumab
5-FU
CDDP
DTX
20 Years - 75 YearsNational Cancer Center, Japan
Immunotherapy With CCRT Followed by Surgery for Locally Advanced ESCC PatientsNCT05743504
Locally Advance...
Tiragolumab
20 Years - National Taiwan University Hospital
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