Spots Global Cancer Trial Database for locally advanced pancreatic cancer
Every month we try and update this database with for locally advanced pancreatic cancer cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.
The following info and data is provided "as is" to help patients around the globe.
We do not endorse or review these studies in any way.
| Study title | NCT ID | Conditions | Interventions | Eligibility | Organization | Link |
|---|---|---|---|---|---|---|
| Metastatic Advanced Pancreas Sorafenib | NCT00758381 | Locally Advance... | Sorafenib 400 m... Gemcitabina, Ci... | 18 Years - 75 Years | Gruppo Italiano per lo studio dei Carcinomi dell'Apparato Digerente | |
| Surufatinib and Serplulimab Combined With AG Regimen Compare With AG Regimen as Conversion Therapy for Patients With Locally Advanced Pancreatic Cancer (SAGE) | NCT05988372 | Locally Advance... | Surufatinib + S... Albumin-paclita... | 18 Years - 75 Years | Sun Yat-sen University | |
| Good Choice of pALliative Chemotherapy to Patient With Pancreatic Cancer ; GemcitAbine Therapy vs FOLFORINOX therapY | NCT04789980 | Locally Advance... Metastatic Panc... | 19 Years - | Boryung Pharmaceutical Co., Ltd | ||
| MicroEnvironment Tumor Effects of Radiotherapy - Comprehensive Radiobiology Assessment TRial | NCT05975593 | Locally Advance... Locally Advance... Locally Advance... Locally Advance... Locally Advance... Cervical Cancer Pancreas Cancer Pancreatic Canc... Cancer of the C... Cancer of the P... | 18 Years - | Washington University School of Medicine | ||
| Prophylactic Administration of Neulapeg (Pegteograstim) in Patients With Locally Advanced or Metastatic Pancreatic Cancer Receiving the Modified FOLFIRINOX | NCT06353581 | Locally Advance... Metastatic Panc... | Neulapeg Control | 19 Years - | Yonsei University | |
| A Study of Locally Advanced Pancreatic Cancer | NCT01063192 | Locally Advance... | Gemcitabine Gemcitabine, Ox... | 20 Years - 75 Years | National Health Research Institutes, Taiwan | |
| Intra-tumoral Mitazalimab (CD40 Antibody) With Irreversible Electroporation (IRE) in Locally Advanced Pancreas Cancer | NCT06205849 | Pancreatic Canc... | IRE + intratumo... NanoKnife | 18 Years - | University of California, San Diego | |
| Study of Modified FOLFIRINOX in Advanced Pancreatic Cancer | NCT01523457 | Metastatic Panc... Pancreatic Canc... | Folfirinox | 18 Years - | Yale University | |
| Combination of SBRT With Sequential S-1 for Treating Locally Advanced Pancreatic Cancer | NCT02704143 | Pancreatic Canc... | combination of ... | 18 Years - | Changhai Hospital | |
| Chemoradiation With Oxaliplatin and Fluorouracil (5FU) for Locally Advanced Pancreatic Cancer | NCT00463840 | Pancreatic Canc... | Oxaliplatin 5FU Radiation Surgery FOLFOX 6 | 18 Years - | NYU Langone Health | |
| Different Patterns of Target Delineation in SBRT for Locally Advanced Pancreatic Cancer | NCT04699539 | Treatment | SBRT Chemotherapy | 18 Years - 75 Years | Changhai Hospital | |
| Study of Lonsurf in Combination With Gemcitabine and Nab-Paclitaxel in Patients With Advanced (PDAC) | NCT04046887 | Pancreatic Canc... Pancreatic Duct... | Lonsurf Gemcitabine Nab-Paclitaxel | 18 Years - | Indiana University | |
| Divestment for Artery-involved Pancreatic Cancer | NCT03443921 | Pancreatic Canc... Locally Advance... Neoadjuvant The... Borderline Rese... | Artery Divestme... Nab-paclitaxel | 18 Years - 80 Years | The First Affiliated Hospital with Nanjing Medical University | |
| Anlotinib, Toripalimab and Nab-paclitaxel in Locally Advanced/Metastatic Pancreatic Cancer | NCT04718701 | Pancreatic Neop... Metastatic Panc... Locally Advance... | Anlotinib+Torip... | 18 Years - 75 Years | The First Affiliated Hospital with Nanjing Medical University | |
| Locally Advanced Pancreatic Cancer Treated With ABLAtivE Stereotactic MRI-guided Adaptive Radiation Therapy | NCT05585554 | Pancreatic Canc... | MRIdian | 18 Years - | Viewray Inc. | |
| Nimotuzumab Plus NALIRIFOX in Locally Advanced Pancreatic Cancer | NCT06429904 | Locally Advance... | Nimotuzumab+ NA... | 18 Years - 75 Years | Peking Union Medical College Hospital | |
| Nimotuzumab Plus NALIRIFOX in Locally Advanced Pancreatic Cancer | NCT06429904 | Locally Advance... | Nimotuzumab+ NA... | 18 Years - 75 Years | Peking Union Medical College Hospital | |
| Prophylactic Administration of Neulapeg (Pegteograstim) in Patients With Locally Advanced or Metastatic Pancreatic Cancer Receiving the Modified FOLFIRINOX | NCT06353581 | Locally Advance... Metastatic Panc... | Neulapeg Control | 19 Years - | Yonsei University | |
| Low-dose Radiotherapy Plus Chemotherapy With Gem-based Doublets and Stereotactic Radiotherapy for Advanced Pancreatic Cancer | NCT02416609 | Pancreatic Canc... | LDR Gem-based doubl... SBRT | 18 Years - | Azienda Ospedaliero-Universitaria di Modena | |
| SBRT Combined With Zimberelimab (GLS-010) in Locally Advanced Pancreatic Cancer (SPARK-1 Study) | NCT06009029 | Locally Advance... | Stereotactic bo... Zimberelimab (G... | 18 Years - 75 Years | Peking University Third Hospital | |
| FOLFOX-A For Locally Advanced Pancreatic Cancer: A Phase II Brown University Oncology Research Group Trial | NCT02578732 | Locally Advance... Pancreatic Canc... | FOLFOXA | 18 Years - | Brown University | |
| Study of Modified FOLFIRINOX in Advanced Pancreatic Cancer | NCT01523457 | Metastatic Panc... Pancreatic Canc... | Folfirinox | 18 Years - | Yale University | |
| Locally Advanced Pancreatic Cancer Treated With ABLAtivE Stereotactic MRI-guided Adaptive Radiation Therapy | NCT05585554 | Pancreatic Canc... | MRIdian | 18 Years - | Viewray Inc. | |
| Ceralasertib (AZD6738) Alone and in Combination With Olaparib or Durvalumab in Patients With Solid Tumors | NCT03682289 | Clear Cell Rena... Locally Advance... Locally Advance... Metastatic Mali... Metastatic Rena... Metastatic Urot... Metastatic Panc... Stage III Pancr... Stage III Renal... Stage IV Pancre... Stage IV Renal ... Endometrial Can... Metastatic Cast... | Ceralasertib Olaparib Durvalumab | 18 Years - | University of California, San Francisco | |
| Celecoxib, Irinotecan and Concurrent Radiotherapy in Preoperative Pancreatic Cancer | NCT00177853 | Pancreatic Canc... | celecoxib irinotecan concurrent radi... | 18 Years - | University of Pittsburgh | |
| Combination of SBRT With Sequential S-1 for Treating Locally Advanced Pancreatic Cancer | NCT02704143 | Pancreatic Canc... | combination of ... | 18 Years - | Changhai Hospital | |
| Intra-arterial Gemcitabine vs. IV Gemcitabine and Nab-Paclitaxel Following Radiotherapy for LAPC | NCT03257033 | Locally Advance... | Gemcitabine nab-paclitaxel RenovoCath | 18 Years - | RenovoRx | |
| SBRT Combined With Zimberelimab (GLS-010) in Locally Advanced Pancreatic Cancer (SPARK-1 Study) | NCT06009029 | Locally Advance... | Stereotactic bo... Zimberelimab (G... | 18 Years - 75 Years | Peking University Third Hospital | |
| Anlotinib, Toripalimab and Nab-paclitaxel in Locally Advanced/Metastatic Pancreatic Cancer | NCT04718701 | Pancreatic Neop... Metastatic Panc... Locally Advance... | Anlotinib+Torip... | 18 Years - 75 Years | The First Affiliated Hospital with Nanjing Medical University | |
| Pancreatic Locally Advanced Irresectable Cancer Ablation | NCT03690323 | Locally Advance... | Radiofrequency ... FOLFIRINOX Nab-paclitaxel ... Gemcitabine | 18 Years - | Academisch Medisch Centrum - Universiteit van Amsterdam (AMC-UvA) | |
| A Registry Study of NanoKnife IRE for Stage 3 Pancreatic Cancer | NCT03899649 | Stage III Pancr... | SOC NanoKnife Syste... | 18 Years - | Angiodynamics, Inc. | |
| Gemcitabine, Oxaliplatin and Capecitabine for Advanced Pancreatic Carcinoma | NCT00744640 | Locally Advance... Metastatic Panc... | gemcitabine, ox... | 18 Years - | University Hospital, Basel, Switzerland | |
| Safety and Efficacy of Irreversible Electroporation for Locally Advanced Pancreatic Cancer | NCT02898649 | Locally Advance... | Irreversible el... | 19 Years - | Yonsei University | |
| Safety and Efficacy of Irreversible Electroporation for Locally Advanced Pancreatic Cancer | NCT02898649 | Locally Advance... | Irreversible el... | 19 Years - | Yonsei University | |
| Chemoradiation With Oxaliplatin and Fluorouracil (5FU) for Locally Advanced Pancreatic Cancer | NCT00463840 | Pancreatic Canc... | Oxaliplatin 5FU Radiation Surgery FOLFOX 6 | 18 Years - | NYU Langone Health | |
| Randomized Controlled Trial of Gemcitabine Combined With 125I Brachytherapy | NCT00644618 | Locally Advance... | gemcitabine 125I brachyther... | 18 Years - 75 Years | Huazhong University of Science and Technology | |
| Vorinostat Plus Radiation Therapy in Pancreatic Cancer | NCT00831493 | Pancreatic Canc... | Chemoradiation ... Vorinostat | 18 Years - | M.D. Anderson Cancer Center | |
| Study of Lonsurf in Combination With Gemcitabine and Nab-Paclitaxel in Patients With Advanced (PDAC) | NCT04046887 | Pancreatic Canc... Pancreatic Duct... | Lonsurf Gemcitabine Nab-Paclitaxel | 18 Years - | Indiana University | |
| Study of Talimogene Laherparepvec (T-VEC) in Pancreatic Cancer | NCT03086642 | Pancreatic Canc... | Talimogene lahe... | 18 Years - | Columbia University | |
| Phase II Study of Hypofractionated Radio-chemotherapy With Gemcitabine Plus Oxaliplatin for Unresectable Nonmetastatic Locally Advanced Pancreatic Cancer. | NCT02035072 | Unresectable Pa... Nonmetastatic P... Locally Advance... | Gemcitabine Oxaliplatin Hypofractionate... | 18 Years - 75 Years | Istituto Scientifico Romagnolo per lo Studio e la cura dei Tumori | |
| Phase I Study Evaluating the Treatment of Patients With Locally Advanced Pancreatic Cancer With Carbon Ion Radiotherapy: The PHOENIX-01 Trial | NCT01795274 | Locally Advance... | Carbon Ion Radi... | 18 Years - | University Hospital Heidelberg | |
| Safety Study of Radiofrequency Ablation of Locally Advanced Pancreatic Cancer | NCT01628458 | Locally Advance... | radiofrequency ... | 18 Years - 80 Years | UMC Utrecht | |
| Nimotuzumab Plus NALIRIFOX in Locally Advanced Pancreatic Cancer | NCT06429904 | Locally Advance... | Nimotuzumab+ NA... | 18 Years - 75 Years | Peking Union Medical College Hospital | |
| The Transformation of Locally Advanced Pancreatic Cancer. | NCT04723030 | Locally Advance... | carleilizumab+a... | 18 Years - | Peking University | |
| Systemic Therapy With a Loco-regional Treatment in Patients With Locally Advanced Pancreatic Cancer | NCT04276857 | Locally Advance... Irreversible El... | Irreversible el... | - | University of Saskatchewan | |
| A Study of Locally Advanced Pancreatic Cancer | NCT01063192 | Locally Advance... | Gemcitabine Gemcitabine, Ox... | 20 Years - 75 Years | National Health Research Institutes, Taiwan | |
| Induction Chemotherapy, FOLFIRINOX Followed With Concurrent Capecitabine and Radiation Therapy in Inoperable Locally Advanced Cancer of the Pancreas | NCT02311439 | Cancer of Pancr... | FOLFIRINOX + CR... | 18 Years - 75 Years | Assiut University | |
| Evaluation of Efficacy and Safety of Neoadjuvant Treatment With Pamrevlumab in Combination With Chemotherapy (Either Gemcitabine Plus Nab-paclitaxel or FOLFIRINOX) in Participants With Locally Advanced Pancreatic Cancer | NCT03941093 | Pancreatic Canc... | Pamrevlumab + G... Placebo + Gemci... | 18 Years - | FibroGen | |
| Stereotactic Radiotherapy (SBRT) in Patients With Locally Advanced Pancreatic Cancer (LAPC) | NCT03648632 | Locally Advance... | Stereotactic Ra... | 18 Years - | Odense University Hospital | |
| FOLFIRINOX Versus OncoSil™ in Addition to FOLFIRINOX in Patients With Locally Advanced Pancreatic Adenocarcinoma | NCT05466799 | Locally Advance... | FOLFIRINOX chem... OncoSil™ | 18 Years - | OncoSil Medical Limited | |
| EndoTAG-1+GEM vs GEM in Patients With Locally Advanced/Metastatic Pancreatic Adenocarcinoma Failed on FOLFIRINOX | NCT03126435 | Metastatic Panc... Locally Advance... Pancreatic Aden... | EndoTAG-1 Gemcitabine | 18 Years - | SynCore Biotechnology Co., Ltd. | |
| Vorinostat Plus Radiation Therapy in Pancreatic Cancer | NCT00831493 | Pancreatic Canc... | Chemoradiation ... Vorinostat | 18 Years - | M.D. Anderson Cancer Center | |
| Combination Study of Capecitabine and Erlotinib Concurrent With Radiotherapy for Non-Operable Advanced Pancreatic Cancer | NCT00565487 | Pancreatic Canc... | Capecitabine, T... | 18 Years - 80 Years | Milton S. Hershey Medical Center | |
| Metastatic Advanced Pancreas Sorafenib | NCT00758381 | Locally Advance... | Sorafenib 400 m... Gemcitabina, Ci... | 18 Years - 75 Years | Gruppo Italiano per lo studio dei Carcinomi dell'Apparato Digerente | |
| Metastatic Advanced Pancreas Sorafenib | NCT00758381 | Locally Advance... | Sorafenib 400 m... Gemcitabina, Ci... | 18 Years - 75 Years | Gruppo Italiano per lo studio dei Carcinomi dell'Apparato Digerente | |
| Systemic Therapy With a Loco-regional Treatment in Patients With Locally Advanced Pancreatic Cancer | NCT04276857 | Locally Advance... Irreversible El... | Irreversible el... | - | University of Saskatchewan | |
| Surufatinib and Serplulimab Combined With AG Regimen Compare With AG Regimen as Conversion Therapy for Patients With Locally Advanced Pancreatic Cancer (SAGE) | NCT05988372 | Locally Advance... | Surufatinib + S... Albumin-paclita... | 18 Years - 75 Years | Sun Yat-sen University | |
| Study of Talimogene Laherparepvec (T-VEC) in Pancreatic Cancer | NCT03086642 | Pancreatic Canc... | Talimogene lahe... | 18 Years - | Columbia University | |
| MicroEnvironment Tumor Effects of Radiotherapy - Comprehensive Radiobiology Assessment TRial | NCT05975593 | Locally Advance... Locally Advance... Locally Advance... Locally Advance... Locally Advance... Cervical Cancer Pancreas Cancer Pancreatic Canc... Cancer of the C... Cancer of the P... | 18 Years - | Washington University School of Medicine | ||
| Ablation of Unresectable Locally Advanced Pancreatic Cancer With Irreversible Electroporation (IRE) System | NCT03614910 | Pancreatic Canc... | Nanoknife Irrev... | 18 Years - | Holy Name Medical Center, Inc. | |
| Anlotinib, Toripalimab and Nab-paclitaxel in Locally Advanced/Metastatic Pancreatic Cancer | NCT04718701 | Pancreatic Neop... Metastatic Panc... Locally Advance... | Anlotinib+Torip... | 18 Years - 75 Years | The First Affiliated Hospital with Nanjing Medical University | |
| Nimotuzumab Plus NALIRIFOX in Locally Advanced Pancreatic Cancer | NCT06429904 | Locally Advance... | Nimotuzumab+ NA... | 18 Years - 75 Years | Peking Union Medical College Hospital | |
| Nab-paclitaxel and S-1 in Patients With Locally Advanced Pancreatic Cancer | NCT03885219 | Locally Advance... | Nab-paclitaxel ... | 18 Years - 70 Years | Peking Union Medical College Hospital | |
| Irreversible Electroporation & Pembro Immunotherapy in Locally Advanced Pancreatic Cancer | NCT06378047 | Pancreatic Canc... Locally Advance... | Pembrolizumab Irreversible El... | 18 Years - | H. Lee Moffitt Cancer Center and Research Institute | |
| Nab-paclitaxel Combined With S-1 as Induction Therapy for Locally Advanced Pancreatic Cancer | NCT03815461 | Locally Advance... | Nab-paclitaxel ... | 18 Years - 75 Years | ChineseAMS | |
| Different Patterns of Target Delineation in SBRT for Locally Advanced Pancreatic Cancer | NCT04699539 | Treatment | SBRT Chemotherapy | 18 Years - 75 Years | Changhai Hospital | |
| A Pivotal Study of Safety and Effectiveness of NanoKnife IRE for Stage 3 Pancreatic Cancer | NCT03899636 | Stage III Pancr... | Modified FOLFIR... NanoKnife Syste... | 18 Years - | Angiodynamics, Inc. | |
| Intra-tumoral Mitazalimab (CD40 Antibody) With Irreversible Electroporation (IRE) in Locally Advanced Pancreas Cancer | NCT06205849 | Pancreatic Canc... | IRE + intratumo... NanoKnife | 18 Years - | University of California, San Diego | |
| A Phase 2 Study of siG12D LODER in Combination With Chemotherapy in Patients With Locally Advanced Pancreatic Cancer | NCT01676259 | Pancreatic Duct... Pancreatic Canc... | siG12D-LODER Gemcitabine+nab... Folfirinox | 18 Years - | Silenseed Ltd | |
| SBRT Combined With Zimberelimab (GLS-010) in Locally Advanced Pancreatic Cancer (SPARK-1 Study) | NCT06009029 | Locally Advance... | Stereotactic bo... Zimberelimab (G... | 18 Years - 75 Years | Peking University Third Hospital | |
| A Registry Study of NanoKnife IRE for Stage 3 Pancreatic Cancer | NCT03899649 | Stage III Pancr... | SOC NanoKnife Syste... | 18 Years - | Angiodynamics, Inc. | |
| Induction Chemotherapy, FOLFIRINOX Followed With Concurrent Capecitabine and Radiation Therapy in Inoperable Locally Advanced Cancer of the Pancreas | NCT02311439 | Cancer of Pancr... | FOLFIRINOX + CR... | 18 Years - 75 Years | Assiut University | |
| Efficacy and Feasibility of Combining FOLFIRINOX and Stereotactic Radiotherapy for Patients With Irresectable Locally Advanced Pancreatic Cancer. | NCT02292745 | Pancreatic Neop... | stereotactic ra... | 18 Years - 75 Years | Foundation for Liver Research | |
| A Phase II Study of Locally Advanced Pancreatic Cancer | NCT01867892 | Pancreatic Canc... | ICT of oxaplipl... ICT of Gemcitab... | 20 Years - 70 Years | National Health Research Institutes, Taiwan | |
| Gemcitabine, Oxaliplatin and Capecitabine for Advanced Pancreatic Carcinoma | NCT00744640 | Locally Advance... Metastatic Panc... | gemcitabine, ox... | 18 Years - | University Hospital, Basel, Switzerland | |
| Ceralasertib (AZD6738) Alone and in Combination With Olaparib or Durvalumab in Patients With Solid Tumors | NCT03682289 | Clear Cell Rena... Locally Advance... Locally Advance... Metastatic Mali... Metastatic Rena... Metastatic Urot... Metastatic Panc... Stage III Pancr... Stage III Renal... Stage IV Pancre... Stage IV Renal ... Endometrial Can... Metastatic Cast... | Ceralasertib Olaparib Durvalumab | 18 Years - | University of California, San Francisco | |
| EndoTAG-1+GEM vs GEM in Patients With Locally Advanced/Metastatic Pancreatic Adenocarcinoma Failed on FOLFIRINOX | NCT03126435 | Metastatic Panc... Locally Advance... Pancreatic Aden... | EndoTAG-1 Gemcitabine | 18 Years - | SynCore Biotechnology Co., Ltd. | |
| Phase I Nab-Paclitaxel Plus Gemcitabine With Proton Therapy for Locally Advanced Pancreatic Cancer (LAPC) | NCT03652428 | Locally Advance... | Gemcitabine Hypofractionate... | 18 Years - 75 Years | University of Maryland, Baltimore | |
| A Pivotal Study of Safety and Effectiveness of NanoKnife IRE for Stage 3 Pancreatic Cancer | NCT03899636 | Stage III Pancr... | Modified FOLFIR... NanoKnife Syste... | 18 Years - | Angiodynamics, Inc. | |
| Good Choice of pALliative Chemotherapy to Patient With Pancreatic Cancer ; GemcitAbine Therapy vs FOLFORINOX therapY | NCT04789980 | Locally Advance... Metastatic Panc... | 19 Years - | Boryung Pharmaceutical Co., Ltd |
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