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Women will be subjected to LOD followed by ovarian stimulation if spontaneous ovulation does not occur within 2 months

Ahmed Gibreel, Dr

Mohamed S Abdelhafez, Dr

The purpose of this study is to compare the efficacy of in vitro fertilization (IVF) versus laparoscopic ovarian drilling (LOD) in infertile women having clomiphene citrate (CC) resistant polycystic ovarian syndrome (PCOS).

Women will be randomly divided into two groups; IVF group and LOD group. Women in the IVF group will undergo one full IVF cycle. Women in the LOD group will be subjected to LOD followed by ovarian stimulation if spontaneous ovulation does not occur within 2 months.

IVF Versus LOD in Women With CC Resistant PCOS

In Vitro Fertilization Versus Laparoscopic Ovarian Drilling in Women With Clomiphene Citrate Resistant Polycystic Ovarian Syndrome

Number of live births divided by the number of women

Number of clinical pregnancies divided by the number of women

Number of multifetal pregnancies divided by the number of clinical pregnancies

Number of first trimester miscarriages (before 12 weeks gestational age) divided by the number of clinical pregnancies

Incidence of OHSS within 9 days of final triggering of oocyte maturation

Mohamed Sayed Abdelhafez

Hormones

PCOS women with AMH level (≥ 7 ng/ml) who underwent LOD in the preceding 3 months prior to IVF/ICSI

PCOS women with AMH level (≥ 7 ng/ml) who did not undergo LOD in the preceding 3 months prior to IVF/ICSI

Women underwent LOD in the preceding 3 months prior to IVF/ICSI

Alaa Wageh, Dr

Waleed El-refaie, Dr

Maher Shams, Dr

To evaluate the effect of performing laparoscopic ovarian drilling (LOD) before proceeding to in vitro fertilization (IVF) or intracytoplasmic sperm injection (ICSI) on the cycle outcomes in polycystic ovarian syndrome (PCOS) patients with high antimullerian hormone (AMH) levels

Retrospective case-control study of PCOS women with high serum AMH level (≥ 7 ng/ml) who were subjected IVF/ICSI. Women underwent LOD in the preceding 3 months prior to IVF/ICSI (study group) will be compared with a control group of women who did not underwent LOD (control group)

LOD Before IVF/ICSI in PCOS Patients With High AMH

Laparoscopic Ovarian Drilling Before IVF/ICSI in Polycystic Ovarian Syndrome Patients With High Antimullarian Hormone

Number of collected oocytes during oocyte retrieval

Calculated for each woman by dividing the number of mature oocytes (MII oocytes) by the total number of oocytes retrieved

Calculated for each couple by dividing the number of fertilized oocytes by the number of injected (or inseminated) oocytes

Number of clinical pregnancies (defined as presence of at least one intrauterine gestational sac with fetal pole and cardiac activity on TVS scan at 4-6 weeks after the ET) divided by the number of ET procedures

Number of gestational sacs on TVS scan at 4-6 weeks after ET divided by the number of transferred embryos

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
IVF Versus LOD in Women With CC Resistant PCOS	NCT02456792	Infertility Polycystic Ovar...	IVF LOD	20 Years - 35 Years	Mansoura University
IVF Versus LOD in Women With CC Resistant PCOS	NCT02456792	Infertility Polycystic Ovar...	IVF LOD	20 Years - 35 Years	Mansoura University
LOD Before IVF/ICSI in PCOS Patients With High AMH	NCT03358199	Infertility Polycystic Ovar...	LOD	18 Years - 35 Years	Mansoura University

Spots Global Cancer Trial Database for lod

Every month we try and update this database with for lod cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for lod

Every month we try and update this database with for lod cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for lod cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.