Neoplasms

Urinary Tract, Sexual Organs, and Pregnancy Conditions

All Conditions

Symptoms and General Pathology

Prostatic Neoplasms

Hypoxia

Urogenital Diseases

Male Urogenital Diseases

Genital Neoplasms, Male

Urogenital Neoplasms

Genital Diseases

Genital Diseases, Male

Prostatic Diseases

Micronutrients

All Drugs and Chemicals

Bone Density Conservation Agents

Anti-Inflammatory Agents

Antineoplastic Agents

Vitamins

Herbal and Botanical

Other Dietary Supplements

Vitamin D

Cholecalciferol

Selenium

Tocopherols

Vitamin E

Tocotrienols

alpha-Tocopherol

Antioxidants

Lycopene

Trace Elements

Hormones

Calcium

Calcium, Dietary

Protective Agents

Radiation-Protective Agents

Vitamin D3

Calciferol

Tocopherol

Tocotrienol

This group of men will be on active treatment (antioxidants) for one year and placebo for the second year.

This group of men will be on placebo for one year and active treatment (antioxidants) for the second year.

Twice a day with meals. Lycopene - 20 mg, Vitamin D3 - 200 IU, Selenium - 100 mcg, Green Tea Extract - 75 mg, Vitamin E - 50 IU

Lycopene, Vitamin D3, Selenium, Green Tea Extract, Vitamin E

Placebo

Neil Fleshner

The purpose of this study is to determine whether antioxidants (vitamin E, selenium and lycopene)can change(reduce)prostate tumor size or blood flow to the prostate as determined by MRI imaging among men on Active Surveillance.

Study of Antioxidants on MRI Detectable Early Stage Prostate Cancer Among Men on Active Surveillance

The Impact of Antioxidants on MRI Markers of Cell Proliferation and Hypoxia Among Men on Active Surveillance With Early Stage Prostate Cancer

The Prostate Cancer Research Foundation of Canada

University Health Network, Toronto

This group of men will be on active treatment (antioxidants)for 6-8 weeks prior to their radical prostatectomy.

This group of men will be on placebo for 6-8 weeks prior to their radical prostatectomy.

The purpose of this study is to see if an intervention of antioxidants(vitamin E, selenium and lycopene) can change (reduce) prostate tumor size and alter certain markers that can affect tumor growth and prostate cancer aggressiveness.

Study of Antioxidants on Prostate Tumors in Men Undergoing Radical Prostatectomy for Prostate Cancer

A Randomized, Double-Blind Study of Combination Vitamin E, Selenium and Lycopene vs. Placebo in Men Undergoing Radical Prostatectomy for Prostate Cancer

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Study of Antioxidants on MRI Detectable Early Stage Prostate Cancer Among Men on Active Surveillance	NCT00744549	Cancer of the P... Prostate Cancer Prostatic Neopl...	Lycopene, Vitam... Placebo	18 Years -	University Health Network, Toronto
Study of Antioxidants on Prostate Tumors in Men Undergoing Radical Prostatectomy for Prostate Cancer	NCT00844792	Cancer of the P... Prostate Cancer Prostatic Neopl...	Lycopene, Vitam... Placebo	18 Years -	University Health Network, Toronto
Study of Antioxidants on MRI Detectable Early Stage Prostate Cancer Among Men on Active Surveillance	NCT00744549	Cancer of the P... Prostate Cancer Prostatic Neopl...	Lycopene, Vitam... Placebo	18 Years -	University Health Network, Toronto

Spots Global Cancer Trial Database for lycopene, vitamin d3, selenium, green tea extract, vitamin e