Neoplasms

Skin and Connective Tissue Diseases

All Conditions

Breast Neoplasms

Breast Diseases

Skin Diseases

Women with proven breast cancer diagnosis. Respond to the First Breast Q questionnaire..

The Second Breast Q questionnaire will be applied to this group that will be composed of the women of the first group submitted to reconstructive breast cancer surgery.

Women with breast cancer will respond to the First Breast Q questionnaire before treatment with breast cancer reconstruction surgery.

First Questionnaire application

Women with breast cancer will respond to the Second Breast Q questionnaire after treatment with breast cancer reconstruction surgery.

Second Questionnaire application

Helio HA Carrara, MD, PhD

Francisco JC Reis, MD, PhD

Data from the National Cancer Institute (Inca) reveal that breast cancer is the most common type of cancer among women worldwide. In Brazil, it is second only to non-melanoma skin cancer. Breast cancer is a feared disease in the female universe because it is considered one of the major causes of death due to neoplasia among women. It brings also the stigma of suffering, mutilation, loss of female identity and loss of body contour. Among other issues, problems with body self-image may have an impact on sexuality and fertility, and also, the incapacity to breastfeed. Breast reconstruction can restore the patient's shape and physical integrity, among other benefits. The research justifies itself because information about the satisfaction of breast reconstruction can be achieved. It is also known that women having breast reconstruction after a mastectomy due to cancer have a favorable evolution. This study will analyze body contour satisfaction of women undergoing mastectomy and breast reconstruction as part of their breast cancer treatment. The Breast Q questionnaire will be used to measure patients satisfaction.

This is a prospective, quasi-experimental study. The subject sample will be composed of women submitted to mastectomy due to breast cancer and to breast reconstruction as part of their treatment. They will be evaluated twice. One when they receive the cancer diagnosis and the other six months after de reconstruction surgery. On both occasions, they will answer the Brest Q questionnaire.

A group of women will be evaluated twice, being one before the intervention and the second after the breast cancer reconstruction surgery

Emotional Evaluation and Reconstructed Breast Satisfaction

Emotional Evaluation and Reconstructed Breast Satisfaction After Breast Cancer Treatment: Breast Q Questionary

Comparison of results between the first and the second Breast Q score. This score represents questionnaries about diferents domains and each question has four possible dimensions. The values of these dimensions varies from 1 to 4 (Likert Scale). The sum of each domain raw score scale will be plotted in the Breast Q Conversion Table to convert the summed domain score to a Equivalent Rasch Transformed Score with values ranging from 0 (worst) to 100 (best).

University of Sao Paulo

Principal Investigator

Urinary Tract, Sexual Organs, and Pregnancy Conditions

Infertility

The cohort consists of immediate breast reconstruction patients who have AlloMax placed at the time of their tissue expander based immediate breast reconstruction.

The study is a prospective multi-centered cohort study designed to determine the safety and efficacy of AlloMax in immediate expander-based breast reconstruction. Specifically, the study is designed to determine if sterility of human acellular dermal matrix results in a lower incidence of infection and seroma. The study will determine if gamma radiation, as a method of terminally sterilizing human acellular dermal matrix, has a negative impact on graft incorporation into the host tissue.

A 1 cm square of AlloMax will be harvested from the first 20 patients for histologic examination to determine wether or not there is neovascularization and collagen deposition.

Evaluating AlloMax in Immediate Expander-Based Breast Reconstruction Study

Evaluating Sterile Human Acellular Dermal Matrix in Immediate Expander-Based Breast Reconstruction: A Multi-centered Prospective Cohort Study

Inova Health Care Services

Ohio State University Comprehensive Cancer Center

Walter Reed Army Medical Center

C. R. Bard

National Center for Plastic Surgery, Virginia

Physician

Carcinoma

Carcinoma, Intraductal, Noninfiltrating

breast cancer patients, intervention = patient navigation

two trained patient navigators will admit breast cancer patients to HCM, navigate them from admission to commencement of first treatment and will collect all pertinent epidemiological data and variables

patient navigation

renato cagnacci neto, MD, MSc

The objective of this observational study is to introduce a patient navigation system within the breast cancer unit at Hospital Central de Maputo (MOZ) and gather data to assess the efficacy of patient navigation in enhancing oncological outcomes among this patient cohort. The primary inquiries it seeks to address are as follows:

* Can patient navigation reduce the duration (in days) between patient admission and the commencement of treatment?
* Does patient navigation influence overall survival rates when juxtaposed with historical cohorts from the local setting? Participants will receive continuous support from a patient navigator starting from admission until the initiation of any oncological treatment.

-General Objective: To implement an oncological navigation platform for breast cancer patients receiving treatment at Maputo Central Hospital (HCM) over a proposed period of 12 months after project approval by the local IRB.

-Specific Objectives:

* Develop an oncological patient navigation system for breast cancer patients treated at HCM.
* Establish a prospective cohort of navigated breast cancer patients (with invasive or ductal carcinoma in situ) treated at HCM in 2024-25.
* Collect diverse epidemiological data from navigated patients during the proposed study period.
* Compare the time interval (in days) between admission to HCM and initiation of cancer treatment (surgery or systemic treatment) among patients in this cohort versus patients already treated in the service with available data in the National Cancer Registry (NCR).
* Compare overall survival between patients in this cohort and a locally published historical cohort from 2020.

A Prospective Cohort With Patient Navigation as an Intervention for Breast Cancer Patients

The Journey of Women With Breast Cancer in Mozambique: What is the Best Path? A Prospective Cohort With Patient Navigation as an Intervention to Reduce Treatment Disparities

we will share all collected IPD with any researchers that contact the PI

time interval (in days) between admission to HCM and initiation of cancer treatment (surgery or systemic treatment)

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Emotional Evaluation and Reconstructed Breast Satisfaction	NCT03777852	Malignant Neopl...	First Questionn... Second Question...	18 Years - 70 Years	University of Sao Paulo
Evaluating AlloMax in Immediate Expander-Based Breast Reconstruction Study	NCT01372917	Malignant Neopl... Acquired Absenc...		25 Years - 65 Years	National Center for Plastic Surgery, Virginia
A Prospective Cohort With Patient Navigation as an Intervention for Breast Cancer Patients	NCT06257888	Breast Neoplasm...	patient navigat...	18 Years -	AC Camargo Cancer Center

Spots Global Cancer Trial Database for malignant neoplasm of the breast