Neoplasms

Skin and Connective Tissue Diseases

All Conditions

Breast Neoplasms

Breast Diseases

Skin Diseases

use of the mamma board during radiotherapy

Mamma board

Jeroen Buijsen, MD

We hypothesize that for large pendulous breasts, breast irradiation in supine and prone position are equivalent with regard to coverage of the PTV, but with a better dose homogeneity in prone position and a smaller radiation exposure of lung and heart.The purpose of this study is to compare the 3-D dose distribution in PTV(Planning Target Volume) and normal tissues in prone position versus supine position.

Local excision followed by adjuvant radiotherapy has become standard treatment for women with early-stage breast cancer. Adjuvant radiotherapy may encounter technical difficulties in patients with pendulous breasts when treated in supine position.

Based upon literature and our own preliminary experiences, we hypothesize that for large pendulous breasts, breast irradiation in supine and prone position are equivalent with regard to coverage of the PTV, but with a better dose homogeneity in prone position and a smaller radiation exposure of lung and heart. However, no quantitative data are yet available to test this hypothesis. Therefore, the aim of our study is to compare the 3-D dose distribution in PTV and normal tissues in prone position versus supine position. For treatment in prone-position an in-house developed device, the "mammaboard" was used.

Prone Breast Irradiation for Pendulous Breasts

Mamma Board Project: Prone Breast Irradiation for Pendulous Breasts

Quantitatively compare the 3 D dose distribution in the PTV (Planning Target Volume) and normal tissues in prone position versus supine position

Quantitatively compare the 3 D dose distribution in the PTV (Planning Target Volume) in prone position versus supine position

PTV coverage (% of PTV \< 95% of prescribed dose) in prone position versus supine position

Doses in organs at risk: lung MLD (Mean Lung Dose)

Doses in organs at risk: heart V30: the volumes (%) of the heart that received \>= 30Gy

Maastricht University

Maastricht Radiation Oncology

Group 1

Age, Categorical

Sex: Female, Male

Netherlands

Region of Enrollment

J. Buijsen,

Dmin (Gy) PTV

Dmean (Gy) PTV

Dmax (Gy) PTV

Prone

Supine

To investigate dose homogeneity and maximum doses, Dmin (minimum Dose), Dmax (maximum Dose) and Dmean (mean Dose) were calculated for prone position versus supine position.

Dose Homogeneity 1: PTV

V105% PTV

V107% PTV

To investigate dose homogeneity V105% (volume of tissue receiving more than 105% of the prescribed dose) and V107% (volume of tissue receiving more than 107% of the prescribed dose) were calculated for prone position versus supine position.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Prone Breast Irradiation for Pendulous Breasts	NCT00181363	Breast Cancer	Mamma board	18 Years -	Maastricht Radiation Oncology
Prone Breast Irradiation for Pendulous Breasts	NCT00181363	Breast Cancer	Mamma board	18 Years -	Maastricht Radiation Oncology
Prone Breast Irradiation for Pendulous Breasts	NCT00181363	Breast Cancer	Mamma board	18 Years -	Maastricht Radiation Oncology

Spots Global Cancer Trial Database for mamma board

Every month we try and update this database with for mamma board cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for mamma board

Every month we try and update this database with for mamma board cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for mamma board cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.