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Urinary Tract, Sexual Organs, and Pregnancy Conditions

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Papillomavirus Infections

Papilloma

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Sexually Transmitted Diseases, Viral

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Disease Attributes

The study population consists of couples under care for infertility in the participating centers. Gamete donations are not included. Please see inclusion and exclusion criteria.

Intervention: HPV screening for women Intervention: HPV screening for men

Stéphane Droupy, MD, PhD

The main objective of this study is to investigate the association between the presence of HPV infection in one or both members of infertile/sub-infertile couples and the outcome of pregnancies obtained by assisted reproduction.

The success of assisted medical procreation is defined as achieving a pregnancy resulting in the birth of a living, viable child.

The secondary objectives of this study are:

A. To study the alterations of sperm present in infertile men according to the presence of HPV in semen.

B. Identify the specific HPV genotypes involved.

C. To study a potential link between HPV and embryonic characteristics (as classified by Giorgetti)

D. To study a potential link between HPV and survival of the conceptus: products of miscarriage or stillbirth, duration of pregnancy, birth weight.

E. To study a potential link between HPV and fetal malformations.

Samples collected (semen and cervical smears) will be sent to the Virology Laboratory of the Hôpital St-Eloi, CHU Montpellier, for analysis. After analysis, the remains of viral DNA will be banked for future studies on the Papilloma Virus.

Human Papillomavirus and Rate of Pregnancy Achieved Via Medically Assisted Procreation

Study of the Role of Infection by Human Papillomavirus (HPV) in the Success Rate of Pregnancies Achieved Via Medically Assisted Procreation

Beta HCG - Human Chorionic Gonadotropin (pregnancy test)

Centre Hospitalier Universitaire de Nīmes

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Human Papillomavirus and Rate of Pregnancy Achieved Via Medically Assisted Procreation	NCT01894425	Infertility Sub-fertility Papillomavirus ...		18 Years - 60 Years	Centre Hospitalier Universitaire de Nīmes
Human Papillomavirus and Rate of Pregnancy Achieved Via Medically Assisted Procreation	NCT01894425	Infertility Sub-fertility Papillomavirus ...		18 Years - 60 Years	Centre Hospitalier Universitaire de Nīmes

Spots Global Cancer Trial Database for medically assisted procreation