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Brief Title: Human Papillomavirus and Rate of Pregnancy Achieved Via Medically Assisted Procreation
Official Title: Study of the Role of Infection by Human Papillomavirus (HPV) in the Success Rate of Pregnancies Achieved Via Medically Assisted Procreation
Study ID: NCT01894425
Brief Summary: The main objective of this study is to investigate the association between the presence of HPV infection in one or both members of infertile/sub-infertile couples and the outcome of pregnancies obtained by assisted reproduction. The success of assisted medical procreation is defined as achieving a pregnancy resulting in the birth of a living, viable child.
Detailed Description: The secondary objectives of this study are: A. To study the alterations of sperm present in infertile men according to the presence of HPV in semen. B. Identify the specific HPV genotypes involved. C. To study a potential link between HPV and embryonic characteristics (as classified by Giorgetti) D. To study a potential link between HPV and survival of the conceptus: products of miscarriage or stillbirth, duration of pregnancy, birth weight. E. To study a potential link between HPV and fetal malformations.
Minimum Age: 18 Years
Eligible Ages: ADULT
Sex: ALL
Healthy Volunteers: No
CHU de Montpellier - Hôpital Saint-Eloi, Montpellier cedex 5, , France
CHU de Montpellier - Hôpital Arnaud de Villeneuve, Montpellier, , France
CHU de Montpellier - Hôpital Lapeyronie, Montpellier, , France
CHU de Nîmes - Hôpital Universitaire Carémeau, Nîmes Cedex 9, , France
Name: Stéphane Droupy, MD, PhD
Affiliation: Centre Hospitalier Universitaire de Nîmes
Role: STUDY_DIRECTOR