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Lamivudine

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The short-term antiviral therapy (STAT) group was defined as individuals who received HBV antiviral ( antiviral treatments consisted of adefovir (10 mg/day), entecavir (0.5 mg/day), and lamivudine (100 mg/day) )at least 24 weeks before hepatectomy (antiviral therapy still continued during perioperative period). Subjects matching the characteristics of this group were screened from the database according to inclusion and exclusion criteria, and characteristics of this group were collected and recorded for subsequent analysis.

The perioperative antiviral therapy (PAT) group was defined as individuals who received antiviral treatment perioperatively ( antiviral treatments consisted of adefovir (10 mg/day), entecavir (0.5 mg/day), and lamivudine (100 mg/day) ). Subjects matching the characteristics of this group were screened from the database according to inclusion and exclusion criteria, and characteristics of this group were collected and recorded for subsequent analysis.

The study was retrospective and did not involve the application of interventions

Medication history

Bo Wang, MD PhD

Based on the follow-up data of patients who underwent hepatectomy for HBV-related HCC at the First Affiliated Hospital of Xi'an Jiaotong University. patients who met the enrollment criteria were screened for tumor recurrence and survival for statistical analysis to understand the prognosis of patients and analyze the risk factors affecting their prognosis.

A retrospective study of patients who underwent hepatectomy for HBV-related HCC at the First Affiliated Hospital of Xi'an Jiaotong University from January 2016 to June 2019 was conducted. The clinical data of patients, including demographic features, perioperative laboratory values, surgical information, and pathological data, were collected from the official database for patients' data gathering, also, Based on the follow-up data of patients who met the enrollment criteria were screened for tumor recurrence and survival for statistical analysis to understand the prognosis of patients and analyze the risk factors affecting their prognosis.

Effects of Antiviral Therapy on Patients With HBV-related HCC

Effects of Short-term and Perioperative Antiviral Therapy on Prognosis After Hepatectomy for Hepatitis B Virus-related Hepatocellular Carcinoma

The study was based on database from the The First Affiliated Hospital of Xi'an Jiao Tong University , researchers did not have access to patients' information nor raw data unless approved by the Ethics Committee of The First Affiliated Hospital of Xi'an Jiao Tong University.

Postoperative survival time for patients receiving hepatectomy

Recurrence of the hepatocellular carcinoma in patients who underwent hepatectomy

Detailed information such as operation time

First Affiliated Hospital Xi'an Jiaotong University

Principal Investigator

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Effects of Antiviral Therapy on Patients With HBV-related HCC	NCT05406089	Hepatocellular ... Hepatitis B Vir... Survival	Medication hist...	20 Years - 70 Years	First Affiliated Hospital Xi'an Jiaotong University
Effects of Antiviral Therapy on Patients With HBV-related HCC	NCT05406089	Hepatocellular ... Hepatitis B Vir... Survival	Medication hist...	20 Years - 70 Years	First Affiliated Hospital Xi'an Jiaotong University

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