Neoplasms

Skin and Connective Tissue Diseases

All Conditions

Symptoms and General Pathology

Rare Diseases

Melanoma

Skin Neoplasms

Pigmentation Disorders

Neuroendocrine Tumors

Neuroectodermal Tumors

Neuroectodermal Tumors, Primitive

Neoplasms, Germ Cell and Embryonal

Neoplasms by Histologic Type

Neoplasms, Nerve Tissue

Nevus, Pigmented

Nevus

Nevi and Melanomas

Skin Diseases

Neuroendocrine Tumor

Neuroepithelioma

Pigmented skin lesions for which clinical management was prospectively determined to be biopsy of the lesion in toto

MelaFind(R)

Dina Gutkowicz-Krusin, PhD

Joseph V Gulfo, MD, MBA

Harold S Rabinovitz, MD

Armand B Cognetta, Jr, MD

The purpose of this clinical trial is to demonstrate that MelaFind®, a new instrument that uses machine vision for non-invasive early detection of cutaneous pigmented malignant melanoma, is safe and effective. MelaFind® acquires digital images of the lesion with illumination in different spectral bands, from visible to near infrared, and automatically analyzes these images. Diagnostic accuracy of MelaFind® and that of study dermatologists will be evaluated. The reference standard will be final interpretation of lesions by central dermatohistopathology.

Evaluation of Pigmented Skin Lesions With MelaFind(R) System

Sensitivity is the fraction of correctly identified cases of melanoma. Specificity is the fraction of correctly identified cases of non-melanoma.

Number of lesions bioopsied to melanomas detected

MELA Sciences, Inc.

Lesions for which clinical management was prospectively determined to be biopsy of the lesion in toto

Biopsied Pigmented Skin Lesions

Age, Categorical

Age Continuous

Sex: Female, Male

United States

Region of Enrollment

Joanna Adrian / Director, Clinical Operations and Medical Affairs

MelaFind's sensitivity to cutaneous melanoma and 95% confidence intervals were determined.

Specificty of MelaFind and examining dermatologists on the same set of pigmented skin lesions.

MelaFind sensitivity to melanoma

MelaFind specificity for melanoma

All participants with eligible and evaluable lesions were used in analysis of primary outcome measures

Sensitivity and Specificity

Biopsy Ratio

Exploratory Analyses

Overall Study

Spots Global Cancer Trial Database for melafind(r)

Every month we try and update this database with for melafind(r) cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Evaluation of Pigmented Skin Lesions With MelaFind(R) System	NCT00434057	Melanoma	MelaFind(R)	-	MELA Sciences, Inc.
Evaluation of Pigmented Skin Lesions With MelaFind(R) System	NCT00434057	Melanoma	MelaFind(R)	-	MELA Sciences, Inc.

Spots Global Cancer Trial Database for melafind(r)

Every month we try and update this database with for melafind(r) cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for melafind(r) cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.