Neoplasms

Respiratory Tract (Lung and Bronchial) Diseases

All Conditions

Carcinoma, Non-Small-Cell Lung

Lung Neoplasms

Respiratory Tract Neoplasms

Thoracic Neoplasms

Lung Diseases

Respiratory Tract Diseases

Patients in the experimental group will receive a face-to-face group session and a package of healthy lifestyle instant messages, including lifestyle-integrated exercise and physical activity.

The control group will receive a face-to-face group session and a package of healthy lifestyle instant messages, but not related to lifestyle-integrated exercise and physical activity.

The experimental group will receive a face-to-face group session and a package of instant messages related to lifestyle-integrated exercise and physical activity. The lifestyle-integrated exercise is modified from Zero-time exercise. It focuses on four exercise domains that patients with lung cancer could be done at home, including breathing, balance, aerobic, strength, stretching exercises

Lifestyle-integrated exercise

The control group will receive a face-to-face group session and a package healthy living instant messages, but not related to lifestyle-integrated exercise and physical activity.

Healthy living information

LAI Agnes, PhD

Mary Ip, MD

Agnes YK Lai

Agnes YK Lai, PhD

Mary MS Ip, MD

Agnes Lai

Lung cancer is one of the most common cancer diseases, globally and locally. Several health benefits of increased physical activity (PA) have been reported for people with cancer. PA plays a critical role across the cancer trajectory, from prevention through to post-diagnosis and has been proposed as an alternative for improving physical and psychosocial health outcomes, reducing cancer recurrence, and cancer-specific and all-cause mortality.

Although there are a variety of exercise intervention programs for cancer patients, those programs were quite intensive, requiring individuals to commit extra time and effort. Feeling of overwhelmed appointments, lack of time, other barriers, including high cost and limited access to facilities are the most frequently reported barriers that prevent people from starting and maintaining exercise. Hence, the investigators propose to use a brief messaging lifestyle modification intervention program to incorporating simple and easy-to-do patient-centred home-based lifestyle-integrated exercise into daily activities of patients with lung cancer. The aims are to increase patients' physical activity and improve their fatigue, emotion and quality of life, compared to the control group.

Lung cancer is one of the most common cancer, globally and locally. Patients with lung cancer are in a uniquely challenging situation in their disease, comorbidities, and treatment that may lead to worsened symptoms and many negative health consequences, including fatigue, irritability, and impaired daytime functioning.

Physical activity (PA) is defined as 'any bodily movement produced by skeletal muscle that results in energy expenditure'. Several health benefits of increased PA have been reported for people with cancer. PA plays a critical role across the cancer trajectory, from prevention through to post-diagnosis and has been proposed as an alternative for improving physical and psychosocial health outcomes, reducing cancer recurrence, and cancer-specific and all-cause mortality. Although there are a variety of exercise intervention programs for cancer patients, those programs were quite intensive, requiring individuals to commit extra time and effort. Most clinicians underutilise exercise therapy, regardless of its low-cost way to improve symptoms and potential health outcomes. Feeling of overwhelmed appointments, lack of time, other barriers, including high cost and limited access to facilities are the most frequently reported barriers that prevent people from starting and maintaining exercise. Low motivation, fear to exercise, lack of knowledge about benefits are the most common barriers of engaging in physical activity for cancer patients.

Hence, the current proposal is to use a brief messaging lifestyle modification intervention program to incorporating simple and easy-to-do patient-centred home-based lifestyle-integrated exercise (light to moderate physical activity) into daily activities of patients with lung cancer.

The investigators hypothesised that patients in the experimental group would display significantly higher increases in physical activity and improvements in fatigue, emotion and quality of life, compared to the control group.

The objectives are to examine the short-term clinical effects on impacts on fatigue, emotion and quality of life in patients with lung cancer, and to evaluate the feasibility of a brief lifestyle-integrated exercise program to increase physical activity by a pilot study with objective fitness and subjective questionnaire assessment, and focus group interviews.

The control group will receive a face-to-face group session and a package of instant messages related to healthy living information, but no information on lifestyle-integrated exercise and physical activity.

The experimental group will receive a face-to-face group session and a package of information on lifestyle-integrated exercise and physical activity.

Lifestyle Modification Program for Lung Cancer Patients - A Pilot Study

A Brief Messaging Lifestyle Modification Program for Patients With Non-small Cell Lung Cancer - A Pilot Study

The patient consent did not include sharing personal information to other researchers

measured by International Physical Assessment Questionnaire - Short version

measured by European Organisation for Research and Treatment of Cancer and lung module questionnaire

measured by Functional Assessment Cancer Therapy - Lung (FACT-L) questionnaire

measured by Hospital Anxiety and Depression Scale. Each item is answered on a 4-point scale (0-3). The scores for the seven questions on depression are added together to obtain a score ranged from 0 to 21. The higher score the more depressed. The scores for the seven questions on anxiety are added together to obtain a score ranged from 0 to 21. The higher score the more anxiety.

measured by Pittsburgh Sleep Quality Index

measured by Epworth Sleepiness Scale. It is a scale of increasing probability from 0 to 3 for eight different situations that most people engage in during their daily lives, though not necessarily every day. The scores for the eight questions are added together to obtain a score ranged from 0 to 24. The higher score the more sleepiness.

assessed by using a 30-second chair stand test to record the number of stands from chair in 30 seconds

assessed by a single-leg-stance test by recording the time within which the individual could effectively achieve balance on one leg

The University of Hong Kong

Assistant Professor

Skin and Connective Tissue Diseases

Breast Neoplasms

Breast Diseases

Skin Diseases

Single clinician message at T1 aimed at reducing over-screening. No message at T2.

T1 - message from media source aimed at reducing over-screening. T2 - message from clinician aimed at reducing over-screening

T1 - message from a close family member aimed at reducing over-screening. T2 - message from clinician aimed at reducing over-screening

T1 - message from media source aimed at supporting continued screening. T2 - message from clinician aimed at reducing over-screening

T1 - message from a close family member aimed at supporting continued screening.

T2 - message from clinician aimed at reducing over-screening

Different messages describing either the benefits of breast cancer screening aimed at supporting continued screening or messages describing the harms of over-screening and making recommendations to stop screening

messages

Nancy Schoenborn, MD

This is an online survey experiment with data collection over 2 time points two weeks apart. This is Aim 2 of a three-aim R01 project; overall project goal is to better understand how messages from different sources interact to affect older women's breast cancer screening decisions. In this current project, the investigators propose to test the effect of combined exposure to a clinician message + a message from another source (i.e. family/friend or media) on older women's breast cancer screening beliefs, attitudes, and intentions.

In a two-wave national online survey experiment, the investigators will randomly assign 3,000 women 65 years or older without personal history of breast cancer to 6 groups, including two control groups and four experimental groups. The experimental groups will read a message at Time 1 (T1) that may be from either family/friend or the media followed by a second message from a clinician one to two weeks later at Time 2 (T2).

The clinician message will be directed at reducing over-screening, mentioning the harms of over-screening and supporting screening cessation. The investigators will systematically vary the non-clinician message to be either consistent with the clinician message (also mentions harms of over-screening and supports screening cessation) or conflicting (mentions benefits of screening, supports continued screening and opposes screening cessation). The investigators include a no-exposure control group (Group 1) where the participants read no message at either time point and will only be asked the assessment questions. The investigators also include a single exposure group that reads only the clinician message (Group 2).

Participants will be randomly assigned to one of six study groups

Messaging Strategies to Reduce Breast Cancer Over-screening in Older Women

Participants will rate the extent of feeling annoyed after reading the message; assessed by a 5 point likert scale question developed by the investigators.

Participants will rate the extent of feeling interested after reading the message; assessed by a 5 point likert scale question developed by the investigators.

Participants will rate the extent of feeling worried after reading the message; assessed by a 5 point likert scale question developed by the investigators.

Participants will rate the extent of feeling reassured after reading the message; assessed by 5 point likert scale question developed by the investigators.

Participants will be asked to state thoughts and ideas when reading the information.

Participants will rate how much the information discouraged wanting to get a mammogram; assessed by score on a 5 point likert scale question developed by the investigators.

Participants will rate how much the information makes getting a mammogram seem unpleasant; assessed by score on a 5 point likert scale question developed by the investigators.

Participants will rate concern about the health effects of getting a mammogram; assessed by score on a 5 point likert scale question developed by the investigators.

Participants will indicate awareness of medical guidelines concerning women over age 65 who have a lot of health problems, medical guidelines recommend against regular mammograms; assessed by yes/no question developed by the investigators.

Participants will indicate awareness of mammograms that find slow-growing breast cancers that might never cause problems but can lead to unnecessary, risky treatments such as surgery or radiation; assessed by yes/no question developed by the investigators.

Participants will indicate awareness of mammograms that can have false alarm results that may cause stress, anxiety, and require breast biopsies; assessed by yes/no question developed by the investigators.

Participants will rate how confusing mammogram screening recommendations to be; using a 5 point likert scale question developed by the investigators.

Participants will rate whether it is clear or not whether to continue or stop getting mammograms; assessed by 5 point likert scale question developed by the investigators.

Participants will rate whether medical guidelines provide good advice about mammogram screening; assessed by 5 point likert scale question developed by the investigators.

Participants will rate trust in doctors' advice about continuing or stopping getting mammograms; assessed by 5 point likert scale question developed by the investigators.

Participants will rate having mixed feelings about getting mammograms; assessed by 5 point likert scale question developed by the investigators.

Screening intention for a hypothetical patient; assessed by score on a 7 point likert scale question developed by the investigators. 7= definitely should not get a mammogram (i.e. strong support for stopping screening) 1=definitely should get a mammogram (i.e. weak support for stopping screening)

Screening intention assessed by score on a 7 point likert scale question developed by the investigators. 7= very unlikely to get a mammogram (i.e. high intention to stop screening); 1= very likely to get a mammogram (i.e. low intention to stop screening)

Attitude toward mammogram importance; assessed by score on a 5 point likert scale question developed by the investigators.

Attitude toward mammogram benefits; assessed by score on a 5 point likert scale question developed by the investigators.

Attitude toward mammogram being worthwhile; assessed by score on a 5 point likert scale question developed by the investigators.

Message effectiveness toward thinking carefully about getting a mammogram; assessed by a 5 point likert scale question developed by the investigators.

Message effectiveness toward finding out more information about the potential benefits of getting a mammogram; assessed by a 5 point likert scale question developed by the investigators.

Message effectiveness toward finding out more information about the potential downsides of getting a mammogram; assessed by a 5 point likert scale question developed by the investigators.

University of Minnesota

Beth Israel Deaconess Medical Center

National Institute on Aging (NIA)

Johns Hopkins University

Participants in this arm receive information about lung screening purpose, eligibility, benefits and risks in a format which uses text in combination with sequences of pictures to communicate a coherent message. The designs follow conventions from comics/graphic narratives and key stakeholders were involved during the design process.

Participants in this arm receive information about lung screening purpose, eligibility, benefits and risks in a format that uses text with non-narrative pictures for decoration. The pictures have been extracted from the picture narratives being used Arm 1.

Participants in this arm receive information about lung screening purpose, eligibility, benefits and risks in a format that uses text and no pictures.

Lung screening information formatted as picture narratives

Picture narrative information format

Lung screening information formatted as text and non-narrative pictures

Text with pictures information format

Lung screening information formatted as text with no pictures

Text-only information format

Kathryn Robb, PhD

The purpose of this study is to test whether a picture narrative format is more successful, than text with pictures or text alone, in communicating lung screening information (primarily defined by positive attitudes towards the design and increase in knowledge) to people likely to be invited to lung screening where available.

Population screening is key to detecting lung cancer early at a more treatable stage. Uptake of screening should be equitable (i.e., screening benefits all eligible members of the population and does not contribute further to health disparities) and informed (i.e., participants have been involved in the decision to take part and their decision aligns with their values and circumstances). Print decision support materials are the primary mechanism for encouraging engagement with cancer screening and supporting decision making. It is essential that we identify print communication techniques that are effective in informing invitees about lung screening.

The intervention, picture narrative information about lung screening, was previously developed through codesign and prototype testing with people likely to be eligible for lung screening (50 to 75 years old, past or current heavy smokers). Participants will be randomised to one of three groups: Picture narrative format, Text with pictures (control 1) or, Text-only (control 2). This study will assess whether presenting lung screening information in a picture narrative format can improve lung cancer screening knowledge, eligibility self-assessment and attitudes. It will also assess whether perceptions of the information designs can explain any impact of the intervention on these outcomes and whether there are differences across socioeconomic groups.

Participants are randomly assigned to one of three groups. They will receive the same lung screening information but the format of this information will be determined by which group they have been randomised to. All participants will complete a questionnaire immediately after viewing the lung screening information.

The investigators will be blind to intervention allocation because the intervention and questionnaire is to be undertaken independently and remotely by the participants. Although the intervention is not masked from participants, they will not be informed of the purpose of the study or the different conditions until after they have completed all study measures.

The Impact of Picture Narrative Format on Print Lung Screening Communication Outcomes

The Impact of Picture Narrative Format on Knowledge and Acceptability for Lung Screening Print Decision Support Materials

Anonymised individual level study data will be shared via the University of Glasgow's repository Enlighten: Research Data.

Self-reported length of time spent reading the lung screening information.

Participants will be asked 6 multiple choice questions related to the lung screening information presented to the participants during the intervention, covering; Procedure, Eligibility - who, Eligibility - why, Benefits, Adverse effects, Potential results.

Concordance between self-reported personal eligibility for lung cancer screening and actual eligibility based on self-reported age and smoking behaviour.

Self-administered four-item lung cancer screening attitudes measure covering cancer fear, fatalism, benefits, and worry, previously used by Smits et al 2018.

Self-administered nine-item measure rating perceptions of appeal, enjoyment, interest, ease of use, trustworthiness, appropriateness, helpfulness, informativity.

Alongside a single item asking participants whether enough information was provided.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Lifestyle Modification Program for Lung Cancer Patients - A Pilot Study	NCT04105647	Cancer, Lung	Lifestyle-integ... Healthy living ...	18 Years -	The University of Hong Kong
Messaging Strategies to Reduce Breast Cancer Over-screening in Older Women	NCT05821023	Breast Cancer S...	messages	65 Years -	Johns Hopkins University
Messaging Strategies to Reduce Breast Cancer Over-screening in Older Women	NCT05821023	Breast Cancer S...	messages	65 Years -	Johns Hopkins University
The Impact of Picture Narrative Format on Print Lung Screening Communication Outcomes	NCT05016570	Cancer Screenin...	Picture narrati... Text with pictu... Text-only infor...	49 Years - 75 Years	University of Glasgow

Spots Global Cancer Trial Database for messages

Every month we try and update this database with for messages cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for messages

Every month we try and update this database with for messages cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for messages cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.