Neoplasms

All Conditions

Adenocarcinoma

Carcinoma

Neoplasms, Glandular and Epithelial

Neoplasms by Histologic Type

Borut Stabuc, MD PhD

Lojze Smid, MD

Borut Stabuc, MD, PhD

Interventional study of modulation of immune response in patients with pancreatic tubular adenocarcinoma after resection and gemcitabine treatment. When included, patients are pre-treated with moderate doses of cyclophosphamide. Then infusions of allogeneic mononuclear cells are given.

Modulation of the Immune Response in Patients With Pancreatic Tubular Adenocarcinoma

Blood Transfusion Centre of Slovenia

Primoz Rozman, MD PhD

Urinary Tract, Sexual Organs, and Pregnancy Conditions

Rare Diseases

Carcinoma, Renal Cell

Kidney Neoplasms

Urologic Neoplasms

Urogenital Neoplasms

Urogenital Diseases

Female Urogenital Diseases

Pregnancy Complications

Female Urogenital Diseases and Pregnancy Complications

Kidney Diseases

Urologic Diseases

Male Urogenital Diseases

Renal Cell Carcinoma

da Vinci surgical robotic assisted partial nephrectomy

Application of the da Vinci surgical robot to assist the partial nephrectomy

Robotic-assisted partial nephrectomy

Open surgery to conduct the partial nephrectomy

Open partial nephrectomy

Marc O Grimm, MD, Prof

Arnulf Stenzl, MD, Prof

To demonstrate that Robotic-Assisted partial nephrectomy is superior to Open partial nephrectomy in reducing the number of 30 day post-operative complications (Clavien-Dindo Type I-V) for patients with intermediate to high complexity kidney tumors.

Partial nephrectomy is the surgical removal of a kidney tumor while unaffected tissue remains intact so that the kidney function is maintained as far as possible. The more radical procedure would be the complete removal of the kidney, which is not examined in this trial.

Surgery will be randomized either to an open technique involving a large incision or the robotic assisted technique with a few small incisions (keyhole surgery). With robotic assisted surgery the movements of the surgeon are translated into the movement of the instruments.

It is not clear which of the two procedures, open or robotic assisted, has less complications. It is expected that these are different due to the different level of invasiveness and the level of direct access to the organ. This study aims to show that robotic assisted surgery results in less complications than open surgery.

Open vs Robotic Assisted Partial Nephrectomy

Any complication that occurred within 30 days post surgery

Period in which the kidney has no blood supply

Conversion from robotic to open, partial to radical

Volume of blood loss during the surgical procedure

Assessment of pain level via the Brief Pain Inventory (BPI)

Development of neuropathic pain via the DN-4 Patient interview questions

Data will be gathered from routine examination, not a mandatory assessment

Any Clavien-Dindo I-V post-operative complication

Readmission that can be linked to the partial nephrectomy

Re-operation that can be linked to the partial nephrectomy

time from surgery to death from any cause

time from surgery to death due to kidney cancer

time from surgery to first documented recurrence of renal cell carcinoma as defined by the investigator

Time from surgery to the first documented local recurrence e.g. tumor in the operated kidney or in the immediate vicinity (e.g. perirenal fat) at the surgical site. Portside recurrence / incisional, surgical access site recurrence to the affected kidney would also be considered as a local recurrence.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Modulation of the Immune Response in Patients With Pancreatic Tubular Adenocarcinoma	NCT01021800	Pancreatic Tubu...	MIS	30 Years - 70 Years	Blood Transfusion Centre of Slovenia
Open vs Robotic Assisted Partial Nephrectomy	NCT03849820	Renal Cancer	Robotic-assiste... Open partial ne...	18 Years -	Intuitive Surgical

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Spots Global Cancer Trial Database for mis

Every month we try and update this database with for mis cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for mis cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.