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Female Urogenital Diseases and Pregnancy Complications

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mpMRI in addition to the TURBT surgical procedure

mpMRI + Diagnostic TURBT

Chao Family Comprehensive Cancer Center University of California, Irvine

University of California Irvine Medical

Nataliya Mar, MD

This is a pilot, single arm, prospective study that aims to validate the accuracy of the VI-RADS score obtained via multi-parametric magnetic resonance imaging (mpMRI) compared to pathologic cancer stage obtained via diagnostic transurethral bladder tumor resection (TURBT) as well as compare the clinical and quality of life outcomes between these diagnostic modalities in patients with suspected muscle-invasive bladder cancer (MIBC).

mpMRI Compared to Diagnostic TURBT in Patients With Suspected Muscle-Invasive Bladder Cancer

Outcomes With Multi Parametric MRI (mpMRI) Compared to Diagnostic Transurethral Resection of Bladder Tumor (TURBT) in Patients With Suspected Muscle-Invasive Bladder Cancer - a Pilot Study

VI-RADS is a five-point scoring system developed to standardize imaging and reporting of bladder tumor invasiveness on mpMRI. It predicts the degree of possible muscular propria invasion ("muscle-invasiveness") of bladder tumors. Once diagnostic TURBT is performed, the VI-RADS score from mpMRI will be compared to the pathologic tumor (T) stage from a diagnostic TURBT to assess for concordance.

Time from diagnostic test to cancer progression, recurrence, or death.

As assessed by quality of life questionnaires

University of California, Irvine

Associate Professor

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
mpMRI Compared to Diagnostic TURBT in Patients With Suspected Muscle-Invasive Bladder Cancer	NCT06335667	Urothelial Blad... Muscle-Invasive...	mpMRI + Diagnos...	18 Years -	University of California, Irvine
mpMRI Compared to Diagnostic TURBT in Patients With Suspected Muscle-Invasive Bladder Cancer	NCT06335667	Urothelial Blad... Muscle-Invasive...	mpMRI + Diagnos...	18 Years -	University of California, Irvine

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