Behaviors and Mental Disorders

All Conditions

Quality of Life

Active Ingredient Mukbang will be allocated to the participants in the experimental group. The videos which presented the food images, eating sound and a relaxing and pleasant atmosphere will be sent in sequence through the short video platforms on the smart phone to the participants in the experimental group.

Common Mukbang on short video platforms will be allocated to the participants in the conditional group. The Mukbang videos which made and uploaded by popular Mukbang makers will be sent in sequence through the short videos platforms on the smart phone to the participants in the experimental group.

General short videos without food cues will be allocated to the participants in the placebo control group. There will be no restrictions on the type of short video platforms and specific video content.

Mukbang videos include the items which can truly improve the appetite of children with cancer, such as food images, eating sound and interactivity.

Active Ingredient Mukbang

Common Mukbang videos made and uploaded by the famous Mukbang makers.

Common Mukbang

Short videos that don't contain any food cues.

General short videos

Wei Xia, PhD

This study aims to use a three arms randomized clinical trial study to evaluate the effectiveness of the effective constituent of Mukbang in helping children with cancer hospitalized for radiotherapy and chemotherapy to improve their appetite, nutritional status and quality of life.

Cancer has a high incidence among children and adolescents worldwide. In October 2020, the World Health Organization (WHO) released an overview of the Global Action on Childhood Cancer which showed that more than 400,000 children under the age of 19 were diagnosed with cancer worldwide every year. With the development and progress of diagnosis and treatment technology, the health outcome of children with cancer has been greatly improved.

However, the side effects and complications associated with cancer and its treatment can seriously affect the appetite and food intake of children with cancer, resulting in malnutrition and a low quality of life. Therefore, it is very important to effectively improve the appetite of children with cancer during treatment.

Clinical methods to improve the appetite of cancer patients mainly include drugs, diet or nutrition intervention, traditional Chinese medicine and acupuncture, but each intervention has its own advantages and disadvantages which makes the clinical application effect difficult to evaluate, in urgent need of more effective solutions to solve this problem.

Mukbang has shown great potential in helping children with cancer to improve their appetite and food consumption, finally promote nutritional health. What's more, the features of Mukbang, such as high-quality and clear pictures, relaxed atmosphere created by the video makers, sounds while eating, and attractive images of food, may promote viewers' appetite and increase their intake imperceptibly. In addition to that, watching Mukbang while eating can also provide a pleasant eating experience for children with cancer, and the interaction with the Mukbang anchor can also alleviate the loneliness of children who live in hospital for such a long time, so as to enhance the children's taste experience, relieve the negative emotions of loneliness and depression.

Research has found that Mukbang can help people with low appetites increase their food intake and the interest in food. Several studies have shown that videos containing food cues can increase viewers' appetite and decrease feelings of satiety to a certain extent. At the same time, Mukbang can also increase viewers' taste experience on the basis of physics and improve children's interest in food. Thus, Mukbang is a useful tool for those who are struggling to increase the amount and variety of acceptable foods and gain weight. It also suggests that clinicians who treat eating disorders should be aware that Mukbang is a potential factor in their illness, and that effective positive use may be helpful for patients with anorexia or restrictive eating.

Given that, Mukbang will be applied to help children with cancer to improve appetite, nutritional status and quality of life. Studies have found that food images, eating sounds and interactivity of Mukbang may play a leading role in improving appetite. Thus, we defined the active ingredients of Mukbang as food images, eating sound and interactivity in this study. Based on that, this study aims to compare the effect of active ingredient Mukbang, ordinary Mukbang and general short videos without food cues on improving appetite in children with cancer, to provide evidence for larger randomized controlled trials (RCTS) and provide a new direction for clinical departments to develop nutritional interventions and management programs for children with cancer.

Using Mukbang to Improve Appetite, Nutritional Status and Quality of Life in Children With Cancer

The Effectiveness of Mukbang in Helping Children With Cancer Hospitalized for Radiotherapy and Chemotherapy to Improve Appetite, Nutritional Status and Quality of Life: A Randomized Control Trial

The non-identified individual participant data will be shared after the outcomes have been published.

A subjective sensation that stimulates the intake of food to provide the energy necessary for the most basic activities of life, which can be measured by the Cancer Appetite and Symptom Questionnaire (CASQ).

Insufficient or excessive nutrient intake, imbalance of essential nutrients or impaired nutrient utilization, mainly manifested by wasting, stunting, underweight and micronutrient deficiency. Malnutrition is measured by the Subjective Global Nutritional Risk Assessment (SGNA).

Body mass index (BMI), a simple method to evaluate the nutritional status and changes of children with cancer, which will be calculated as weight/height\^2. Weight and height will be combined to report BMI in kg/m\^2.

Individuals in different cultures and value systems experience their living conditions in relation to their goals, expectations, standards and concerns, including their physical health, mental state, independence, social relations, personal beliefs and relationships with the surrounding environment. This target is measured by the pediatric quality of life inventory measurement models 3.0 (PedsQLTM-3.0-cancer).

Wei XIA, PhD

Philosophic Doctor

The fMRI scanning will be divided into 3 parts, includes structural image scans, resting state scans, and task state scans. For the task state function image scanning, participants will be asked to watch the specific video program which includes the food images and eating sound of Mukbang and General short videos without food cues.

Healthy kids and children with cancer hospitalized for radiotherapy and chemotherapy will both accept this intervention.

Specific video program + fMRI will be allocated to the participants in this group. The specific video program includes control videos without food information, eating and food images without sound, chewing and swallowing sound without images, and Interactive content in Mukbang. Participants will undergo structural image scans, resting state scans, and task state scans. The task-fMRI will be performed while watching Mukbang to explore the activation of brain functional areas.

fMRI + Mukbang videos

Wei Xia

This study aims to use the intervention study method to extract and verify the effective ingredients in Mukbang that promote appetite and eating in children with tumor during radiotherapy and chemotherapy, and to analyze and explore their potential mechanisms of action based on functional magnetic resonance imaging.

Cancer has a high incidence among children and adolescents worldwide. In October 2020, the World Health Organization (WHO) released an overview of the Global Action on Childhood Cancer which showed that more than 400,000 children under the age of 19 were diagnosed with cancer worldwide every year. With the development and progress of diagnosis and treatment technology, the health outcome of children with cancer has been greatly improved.

However, the side effects and complications associated with cancer and its treatment can seriously affect the appetite and food intake of children with cancer, resulting in malnutrition and a low quality of life. Therefore, it is very important to effectively improve the appetite of children with cancer during treatment.

Clinical methods to improve the appetite of cancer patients mainly include drugs, diet or nutrition intervention, traditional Chinese medicine and acupuncture, but each intervention has its own advantages and disadvantages which makes the clinical application effect difficult to evaluate, in urgent need of more effective solutions to solve this problem.

Mukbang has shown great potential in helping children with cancer to improve their appetite and food consumption, finally promote nutritional health. Mukbang is a method independently chosen by hospitalized cancer children with radiotherapy and chemotherapy to help promote appetite, which has a natural high acceptance. What's more, the features of Mukbang, such as high-quality and clear pictures, relaxed atmosphere created by the video makers, sounds while eating, and attractive images of food, may promote viewers' appetite and increase their intake imperceptibly.

In addition to that, watching Mukbang while eating can also provide a pleasant eating experience for children with cancer, and the interaction with the Mukbang anchor can also alleviate the loneliness of children who live in hospital for such a long time, so as to enhance the children's taste experience, relieve the negative emotions of loneliness and depression and promote their appetite and interest in food under the condition of ensuring a healthy diet.

Research has found that Mukbang can help people with low appetites increase their food intake and provide vicarious satisfaction to those who overeat. Several studies have shown that videos containing food cues can increase viewers' appetite and decrease feelings of satiety to a certain extent. At the same time, Mukbang can also increase viewers' taste experience on the basis of physics and improve children's interest in food.

Therefore, on the basis of existing studies, this study will use functional magnetic resonance imaging and cross-case analysis to extract and verify the effective ingredients in Mukbang that promote appetite and eating in children with tumor during radiotherapy and chemotherapy, and analyze and discuss their potential mechanism of action, aiming to provide a new direction for clinical departments to develop nutritional intervention measures and management programs for children with cancer.

Research on the Influence of Mukbang on Brain Activation in Children With Cancer Based on fMRI

The Exploration of the Effect of Mukbang on Functional Connectivity of Related Brain Regions in Children With Cancer Hospitalized for Radiotherapy and Chemotherapy Based on fMRI

The outcome can be collected using the Siemens 3T Prisma functional Magnetic Resonance Imaging machine with an Inspur data processing system. The pictures reflect the brain functional areas which can be activated by watching Mukbang.

Participants' self-reported appetite, to reflect the participants' own perceived appetite.

In order to further evaluate the relationship between the functional activities of the appetition-related regions of the brain and appetite, the number of salivation and increased perceived appetite will be recorded by pressing the button during the MRI scan.

Associate Professor

Nutritional and Metabolic Diseases

Malnutrition

Children with cancer who received at least one radiotherapy and chemotherapy during hospitalization

At baseline, the children's demographics, disease-related data, characteristics of "Mukbang"watching behavior, appetite, nutritional status, and quality of life data were collected. From the first day of radiotherapy or chemotherapy, 3 meals a day for 5 consecutive days were followed to track the children's appetite status and the characteristics of "Mukbang"watching behavior. Their nutritional status and quality of life were tracked at the end of treatment or when they were discharged from the hospital.

Questionnaires set

Yuxue Xiao, Master

The purpose of this study is to record the "Mukbang" watching behavior and appetite of children with cancer during inpatient radiotherapy and chemotherapy through intensive longitudinal study, explore their correlation, and the impact on their nutritional status and quality of life, and formulate for clinical departments relevant interventions and management options provide a theoretical basis.

World Health Organization（WHO） data shows that the prevalence of malnutrition in children with cancer is as high as 75%, which leads to decreased immune function in children with cancer, unsatisfactory treatment effect, increased adverse clinical outcomes, early tumor recurrence, prolonged recovery time, and death. risk factors such as increased rates. The "Global Childhood Oncology Initiative" proposed by WHO in 2020 pointed out that reducing hunger and malnutrition and improving the outcomes of children with cancer are one of the main tasks of providing best practices in pediatric oncology care.

The excessive consumption of the body caused by the cachexia of the tumor itself cannot be changed. Nutritional intake is the only adjustable factor for malnutrition in children with tumors. Loss of appetite is the main reason for insufficient nutritional intake. Numerous clinical studies have explored the nutritional management of children with cancer. However, most nutritional interventions are ineffective due to poor appetite and food intake in children.

The investigation in the clinical ward found that in order to cope with the problem of loss of appetite, many children with cancer took the initiative to watch "Mukbang" during hospitalization to relieve gastrointestinal symptoms and increase appetite. At present, studies have shown that "Mukbang" may have the potential to improve the appetite of children with tumors. In addition, watching "Mukbang" is a way that children actively choose to increase their appetite, which has better acceptability.

Intensive longitudinal study can explain the dynamic changes of children's behavior and appetite when watching "Mukbang" videos by sampling in a natural context for a short period of time and multiple times, and based on real-time data, further Explain in detail the persistent effect of watching "Mukbang" video behaviors on appetite.

The Association Between Watching Mukbang Videos and the Appetite of Children With Cancer

The Association of Mukbang Watching Behavior and the Appetite of Children With Cancer Hospitalized for Radiotherapy and Chemotherapy: An Intensive Longitudinal Study

The appetite will be assessed by Cancer Appetite and Symptom Questionnaire(CASQ) . The questionnaire consisted of 12 items, each item ranged from 0 to 4 points, and the total score of the questionnaire ranged from 0 to 48 points. The lower the total score, the worse the patient's appetite.

The "Mukbang" watching features will be assessed by a questionnaire designed by the researcher and recorded by the subjects themselves, including watching time, watching rate, watching preferences and watching experience.

The nutritional status will be assessed by using the Subjective Global Nutritional Assessment（SGNA）. Assessment included the children's recent height, weight, parental height, dietary intake, changes in appetite, frequency and duration of gastrointestinal symptoms, and recent physical activity and changes. This provides a comprehensive assessment of the nutritional status of children, with ratings classified as well-nourished, moderately malnourished or severely malnourished.

The quality of life in children with cancer will be assessed by using the Pediatric Quality of Life Inventory Measurement Models 3.0（PedsQLTM-3.0-cancer）.The model has a total of 27 items, including 8 subscales, each item used a 5-point Likert scale, (0=never, 1=almost never, 2=sometimes, 3=often, 4 = almost always), higher scores indicate better quality of life.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Using Mukbang to Improve Appetite, Nutritional Status and Quality of Life in Children With Cancer	NCT05922553	Children With C...	Active Ingredie... Common Mukbang General short v...	6 Years - 18 Years	Sun Yat-sen University
Research on the Influence of Mukbang on Brain Activation in Children With Cancer Based on fMRI	NCT05922566	Children With C...	fMRI + Mukbang ...	10 Years - 18 Years	Sun Yat-sen University
The Association Between Watching Mukbang Videos and the Appetite of Children With Cancer	NCT05493020	Mukbang	Questionnaires ...	3 Years - 18 Years	Sun Yat-sen University

Spots Global Cancer Trial Database for mukbang

Every month we try and update this database with for mukbang cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for mukbang

Every month we try and update this database with for mukbang cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for mukbang cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.