Neoplasms

All Conditions

Musculoskeletal Diseases

Soft Tissue Neoplasms

Bone Neoplasms

Bone Diseases

In en bloc resection, the osteotomy sites were determined by navigation guidance. For curettage, we monitored curette in real-time with navigation.

Navigation surgery

Navigation system

Sung Wook Seo

Hee Jung Jin, bachelor's degree

Bone tumor near the articular cartilage is hard to remove sufficiently without damaging adjacent joint. The purpose of this study was to evaluate the feasibility of navigation-assisted surgery for saving joint in bone tumor resection or curettage. In this study, the investigators hypothesized that computer-assisted surgery is feasible method to get both enough margin and joint salvage. Each of them is important intermediate factor for either oncologic outcome or functional outcome respectively. The investigators designed this study to find what proportion of patients who underwent computer-assisted resection could get enough margins using some criteria obtained by overlapping preoperative and postoperative images. The investigators also evaluated whether computer-assisted surgery can be feasible for joint saving using some criteria including functional outcome.

Navigation Surgery for Bone and Soft Tissue Tumor

Pre-operative and post-operative CT or MRI images were fused using image fusion application of navigation software (Striker, Mahwah, NJ)in order to evaluate the resection margin.

1) Oncological outcome after 6 month or 12 month from surgery like patient survival or tumor recurrence (tumor recurrence was diagnosed with PET CT or MRI according to the nature of original tumor), 2) functional scores were assessed by evaluation systems of the Musculoskeletal Tumor Society (MSTS)and Toronto Extremity Salvage Score (TESS).

Samsung Medical Center

Sungwook Seo

Symptoms and General Pathology

Neoplasm Metastasis

Neoplastic Processes

Patients operated with an early secondary alveolar grafting between the ages of 4 to 7 years with a 3D imaging (CT, CBCT or scan) performed between the ages of 8 to 11 years.

Patients operated with a late secondary alveolar graft between the ages of 8 to 11 years with a 3D imaging (CT, CBCT or scan) performed at least 1 year after the operation.

Guillaume CAPTIER, MD.PhD

Study about the comparison of post-operative results of secondary alveolar grafts according to two age groups: early secondary (4 to 7 years) versus late secondary (8 to 11 years) using a recently proposed score based on post-operative 3D CT analysis.

Comparison of the initial results of the graft in the two groups, with a reference 2D score and evaluation of the concordance between the results found with this score and those of the 3D score.

Finally, comparison of graft bone densities and nasal floor level (using 3D visualization) on post-operative TDMs in the 2 groups.

The aim of this study is to determine the optimal age for grafting using three-dimensional CT assessment.

Radiographic Evaluation of Secondary Alveolar Bone Grafting in Patients With Alveolar Cleft

3D Radiographic Evaluation of the Long Terms Results of Secondary Alveolar Bone Grafting in Patients With Alveolar Cleft: Comparison of Early Versus Late Secondary Grafting SABG : Secondary Alveolar Bone Grafting

Kamperos's score (a post-operative tri-dimensional scanographic score) This score includes 3 items measured on the post-operative CT: graft bone thickness (0 to 2), bone graft height (0 to 4) and nasal floor height (0 to 4).

A total score of 0 to 8 is considered a failure and 9 to 10 a success

Bergland's score (a post-operative two-dimensional radiographic score) Post-operative two-dimensional radiographic score : Use of the Bergland score (reference score).

This score evaluates the height of the inter-dental bone septum up to the cemento - enamel junction (1 to 4).

Post-operative average bone density of the grafted area : in axial slice using radiological image processing software (Myrian®) to segment regions of interest.

Nasal floor level by analyzing the level of the piriform orifice in relation to the grafted area using 3D visualization by volume rendering: percentage of the height between the piriform orifice to the alveolar crest of the grafted side relative to the controlateral side (the healthy side considered as the reference 100% side).

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Navigation Surgery for Bone and Soft Tissue Tumor	NCT01179698	Bone Tumors	Navigation surg... Navigation syst...	-	Samsung Medical Center
Radiographic Evaluation of Secondary Alveolar Bone Grafting in Patients With Alveolar Cleft	NCT04845308	Alveolar Cleft		8 Years -	University Hospital, Montpellier
Navigation Surgery for Bone and Soft Tissue Tumor	NCT01179698	Bone Tumors	Navigation surg... Navigation syst...	-	Samsung Medical Center

Spots Global Cancer Trial Database for navigation system