Neoplasms

Skin and Connective Tissue Diseases

All Conditions

Breast Neoplasms

Breast Diseases

Skin Diseases

* Standard MRI will be performed
* Supine MRI will be performed
* Participant will receive mammography and ultrasound
* Breast Radiologist will take a brief survey.
* Patients will undergo upfront surgery or receive Neoadjuvant Therapy per standard of care
* Standard of care will be performed

Supine MRI

Neoadjuvant Therapy (NAT)

Ultrasound

Mammography

Standard of Care

Standard MRI

Tari King, MD

This research study involves the use of a common breast imaging modality (magnetic resonance imaging, 'MRI') and is investigating its role in evaluating surgical decision making for breast cancer when it is performed with the patient in a new position (lying on one's back) as opposed to in the standard position (lying on one's stomach).

The procedure involved is called a supine breast magnetic resonance imaging (MRI).In this study, the investigators are evaluating the value of supine MRI in surgical decision making for women with breast cancer either undergoing upfront surgery or for those anticipating surgery after receiving neoadjuvant therapy.

The purpose of this study is to assess the value of supine breast MRI as a new imaging method to assist in surgical treatment planning. It is possible that the use of supine breast MRI will help your doctor see the size and location of tumors more accurately

Supine MRI in Breast Cancer Patients Undergoing Upfront Surgery or Receiving Neoadjuvant Therapy

Comparing tumor size as measured on prone MRI images with tumor size as measured on final pathology among pts undergoing upfront surgery and among pts undergoing neoadjuvant chemotherapy. In the neoadjuvant chemotherapy group the post-treatment MRI images were used.

Compared tumor size as reported by radiologist on the clinical report between Supine Breast MRI and The Pathologic Residual Tumor Size as reported by the pathologist on the final surgical pathology report..

Correlate maximal tumor Dimensions as measured by the radiologist between the Prone and Supine MRI Images

Reported as the proportion of surgeons answering yes. Surgeon reported answers to surveys asking if the supine MRI helped in the performance of the surgical procedure.

Dana-Farber Cancer Institute

Principal Investigator

The definition does not differ from the clinicaltirals.gov definitions.

* Standard MRI will be performed
* Supine MRI will be performed
* Participant will receive mammography and ultrasound
* Breast Radiologist will take a brief survey.
* Patients will undergo upfront surgery or receive Neoadjuvant Therapy per standard of care
* Standard of care will be performed

Supine MRI

Neoadjuvant Therapy (NAT)

Ultrasound

Mammography

Standard of Care

Standard MRI

Age, Categorical

Age, Continuous

Sex: Female, Male

Ethnicity (NIH/OMB)

Race (NIH/OMB)

United States

Region of Enrollment

Dr. Tari King

Comparison of tumor size between standard (prone) MRI imaging and surgical pathology

Standard (Prone) MRI Tumor Imaging

Analysis performed of 38 patients with Prone MRI imaging measurements and surgical pathology measurements

Correlation Between Prone Breast MRI for Estimation of Tumor Size and Final Pathology Tumor Size

Patients with both supine MRI measurements and pathologic tumor size measurements

Supine MRI and Pathologic Tumor Size

We analyzed MRI tumor size and pathologic tumor size for 26 pts with both supine MRI measurements and final pathology measurements

Correlation Between Supine Breast MRI for Estimation Of Tumor Size and The Pathologic Tumor Size

comparison of maximum tumor dimension as measured on prone MRI imaging versus supine MRI imaging

Patients With Imaging in Both the Prone and Supine Positions

40 pts who had both a prone and a supine MRI measurement of tumor size

Correlation of Breast Tumor Dimensions Between Prone and Supine Imaging Positions.

Patients having supine MRI imaging and proceeding with breast conserving surgery

Breast Conserving Surgery Patients

among 30 pts analyzed, 13 surgeons reported the supine imaging was helpful whereas 17 surgeons reported the imaging was not helpful

The Perceived Benefit Of Supine MRI For Surgical Planning As Measured By The Collective Results Of A Survey Of Surgeons Performing Breast-conserving Therapy (BCT) In Our Study Patient Population

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Supine MRI in Breast Cancer Patients Undergoing Upfront Surgery or Receiving Neoadjuvant Therapy	NCT02956473	Breast Cancer	Supine MRI Neoadjuvant The... Ultrasound Mammography Standard of Car... Standard MRI	18 Years -	Dana-Farber Cancer Institute
Supine MRI in Breast Cancer Patients Undergoing Upfront Surgery or Receiving Neoadjuvant Therapy	NCT02956473	Breast Cancer	Supine MRI Neoadjuvant The... Ultrasound Mammography Standard of Car... Standard MRI	18 Years -	Dana-Farber Cancer Institute

Spots Global Cancer Trial Database for neoadjuvant therapy (nat)