Symptoms and General Pathology

All Conditions

Neoplasms

Urinary Tract, Sexual Organs, and Pregnancy Conditions

Gland and Hormone Related Diseases

Syndrome

Polycystic Ovary Syndrome

Cysts

Ovarian Cysts

Ovarian Diseases

Adnexal Diseases

Genital Diseases, Female

Genital Diseases

Urogenital Diseases

Female Urogenital Diseases

Pregnancy Complications

Female Urogenital Diseases and Pregnancy Complications

Gonadal Disorders

Endocrine System Diseases

Women previously diagnosed with PCOS not using hormonal therapy and without other significant health or endocrine issues

Women self-identifying as generally healthy, not using hormonal therapy, and without any significant health or endocrine issues

This observational study will only collect data, not provide any intervention to participants.

No intervention study

Chris D'Adamo, PhD

Chris Mason, PhD

The purpose of this research study is to explore the relationship between the gut microbiome and hormone levels in women diagnosed with PCOS and determine whether there are differences in the gut microbiome between women with PCOS and women without PCOS.

Consented, enrolled participants will complete a health questionnaire, complete a fasted blood draw at a local laboratory, and provide a stool, saliva, and vaginal swab sample for comprehensive biomarkers, hormones, metagenomics, and metabolomics analysis.

Whole blood, saliva, vaginal microbiome, stool microbiome

A Multi-omic Approach to Evaluate and Characterize the Polycystic Ovary Syndrome (PCOS) Phenotype

Understand phenotypical differences from biological samples comparing women with and without PCOS. Vaginal swabs are to be collected by women and analyzed with metagenomics and metabolomics sequencing.

Understand phenotypical differences from biological samples comparing women with and without PCOS. Stool samples are to be collected by women and analyzed with metagenomics sequencing.

Understand phenotypical differences from biological samples comparing women with and without PCOS. Venipuncture blood draws are to be completed and analyzed by a commercial laboratory, for a comprehensive analysis of targeted hormones and untargeted metabolic systems.

Understand phenotypical differences from biological samples comparing women with and without PCOS. Saliva samples are to be collected and analyzed by a commercial laboratory for DNA and metabolomics.

University of Maryland, Baltimore

Onegevity Health

Mouth and Tooth Diseases

Digestive System Diseases

Stomatitis

Mucositis

Gastroenteritis

Gastrointestinal Diseases

Mouth Diseases

Stomatognathic Diseases

no intervention study

Yonghui Jeong

Boyoun Seo

Do-Youn Oh

Do-Youn Oh, PhD

to survey oral mucositis after chemotherapy and Concurrent chemoradiotherapy in Korean cancer patients

Observational Study of Anti-Cancer Therapy Induced Oral Mucositis in Korean Cancer Patients

Otsuka Pharmaceutical Co., Ltd.

Korea Otsuka Pharmaceutical Co., Ltd.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
A Multi-omic Approach to Evaluate and Characterize the Polycystic Ovary Syndrome (PCOS) Phenotype	NCT04981275	Polycystic Ovar...	No intervention...	18 Years - 40 Years	Onegevity Health
A Multi-omic Approach to Evaluate and Characterize the Polycystic Ovary Syndrome (PCOS) Phenotype	NCT04981275	Polycystic Ovar...	No intervention...	18 Years - 40 Years	Onegevity Health
Observational Study of Anti-Cancer Therapy Induced Oral Mucositis in Korean Cancer Patients	NCT00549952	Oral Mucositis	no intervention...	19 Years -	Korea Otsuka Pharmaceutical Co., Ltd.

Spots Global Cancer Trial Database for no intervention study