Neoplasms

All Conditions

Symptoms and General Pathology

Adenoma

Recurrence

Colonic Polyps

Polyps

Disease Attributes

Neoplasms, Glandular and Epithelial

Neoplasms by Histologic Type

Herbal and Botanical

All Drugs and Chemicals

Cola

Patients do not receive Snare Tip Soft Coagulation to the edge of the endoscopic resection defect

Patients to receive Snare Tip Soft Coagulation to the edge of the endoscopic resection defect

Snare Tip Soft Coagulation

No Snare Tip Soft Coagulation

Michael Bourke, FRACP, MBBS

Recurrence after endoscopic mucosal resection of laterally spreading lesions (LSL) \>= 20mm in size occurs in approximately 20% of cases at surveillance colonoscopy. We aim to evaluate the efficacy of prophylactic adjuvant thermal ablation of the EMR mucosal defect margin in reducing adenoma recurrence following colonic EMR.

Patients were blinded to the treatment allocation. The endoscopists performing the index and surveillance procedures were not blinded to the treatment.

Soft Coagulation for the Prevention of Adenoma Recurrence

Soft Coagulation for the Prevention of Adenoma Recurrence After Endoscopic Mucosal Resection (EMR) of Large Sessile Colonic Polyps: A Multicentre, Randomized Trial.

Presence of residual/recurrent adenoma at the EMR scar at endoscopic follow-up

Presence of residual/recurrent adenoma on biopsy of the endoscopic resection scar

Rate of 'en bloc resection' (removing entire lesion in one snare) with histologically confirmed clear margins

The number of snare resections needed to achieve complete clearance

Bleeding after EMR requiring admission or repeat intervention

Number of injections required for haemostasis

Delayed perforation requiring intervention or readmission

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Soft Coagulation for the Prevention of Adenoma Recurrence	NCT01789749	Colonic Adenoma...	Snare Tip Soft ... No Snare Tip So...	18 Years -	Western Sydney Local Health District
Soft Coagulation for the Prevention of Adenoma Recurrence	NCT01789749	Colonic Adenoma...	Snare Tip Soft ... No Snare Tip So...	18 Years -	Western Sydney Local Health District

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