Urinary Tract, Sexual Organs, and Pregnancy Conditions

All Conditions

Infections

Immune System Diseases

Neoplasms

Blood and Lymph Conditions

Symptoms and General Pathology

Digestive System Diseases

Kidney Diseases

Autoimmune Diseases

Hematologic Neoplasms

Communicable Diseases

Gastrointestinal Diseases

Intestinal Diseases

Urogenital Diseases

Hematologic Diseases

Disease Attributes

Healthy subjects with no history of chronic disease

Subjects that have been diagnosed with a condition of interest such as Diabetes, NASH, Breast Cancer, Endometriosis, or other designated condition.

Observational Study Only. NO Intervention.

Study purpose: to explore the entire spectrum of proteomic and genomic changes (amongst others) involved in diseases and in healthy/control populations. The Study is designed to discover biomarkers, develop and validate diagnostic assays, instruments and therapeutics as well as other medical research. Specifically, researchers may analyze proteins, RNA, DNA copy number changes, including large and small (1,000-100,000 kb) scale rearrangements, transcription profiles, epigenetic modifications, sequence variation, and sequence in both diseased tissue and case-matched germline DNA from Subjects.

The primary objective of this Study is to collect high-quality tissue, whole teeth, and biofluid Specimens, and associated Clinical Data from consented Subjects.

The secondary objective of this Study is to test Specimens and associated Clinical Data to confirm pathology diagnosis and correlation of microscopic evaluation with the provided information, to assess RNA and DNA integrity or degradation, and provide overall quality control evaluations.

This Study will collect leftover Specimens that are taken during standard medical care procedures (for example, tissues, whole teeth, blood, saliva, urine, fluids, and cells). Samples will first be processed for clinical purposes, and any discarded portions of the Specimen(s) will be provided to the Sponsor for the Study purposes.

Non-Surplus Specimens Types to be Collected for Study:

Blood Tooth Bone marrow aspirate Aqueous humor Urine Perineal specimens Rectal specimens Urethral specimens Nasal/Nasopharyngeal and throat specimens Cheek (buccal) specimens Saliva (Sputum) Oral rinse Stool samples Vaginal and cervical specimens Endometrial (uterus) samples Vaginal lavage (wash)

AUD Biomarkers Study (Proteomic and Genomic Analysis of Biospecimens)

AUD Biomarkers Study (Proteomic and Genomic Analysis of Biospecimens Involved in Diseases and Healthy Populations)

We will total the number of subjects and characterize the totals by disease state, gender, ethnicity and specimens contributed

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
AUD Biomarkers Study (Proteomic and Genomic Analysis of Biospecimens)	NCT05889806	Oncology Hematologic Mal... Gastro-Intestin... Autoimmune Dise... Pregnancy Relat... Infectious Dise... Cardiovascular ... Genitourinary D... Renal Disease	Observational S...	18 Years -	Audubon Bioscience
AUD Biomarkers Study (Proteomic and Genomic Analysis of Biospecimens)	NCT05889806	Oncology Hematologic Mal... Gastro-Intestin... Autoimmune Dise... Pregnancy Relat... Infectious Dise... Cardiovascular ... Genitourinary D... Renal Disease	Observational S...	18 Years -	Audubon Bioscience

Spots Global Cancer Trial Database for observational study only. no intervention.