Neoplasms

All Conditions

Head and Neck Neoplasms

All Drugs and Chemicals

Anti-Arrhythmia Agents

Channel Blockers

Analgesics

Anticonvulsants

Central Nervous System Depressants

Reproductive Control Agents

Bone Density Conservation Agents

Rocuronium

Magnesium Sulfate

Anesthetics

Calcium

Calcium Channel Blockers

Calcium, Dietary

Hormones

Tocolytic Agents

In the magnesium group, patients received MgSO4 30 mg/kg in 0.9% physiological saline (total volume 100 ml) intravenously, for 10 min, and then continuous intravenous infusion of MgSO4 at a rate of 1 g/h during the surgical procedure until the maximum of 3 h.

Controls received 100 ml of 0.9% physiological saline, for 10 min, and then continuous intravenous infusion of saline at a rate of 33 ml/h during the surgical procedure until the maximum of 3 h.

MgSO4 30 mg/kg in 0.9% physiological saline (total volume 100 ml) intravenously, for 10 min, and then continuous intravenous infusion of MgSO4 at a rate of 1 g/h during the surgical procedure until the maximum of 3 h

100 ml of 0.9% physiological saline, for 10 min, and then continuous intravenous infusion of saline at a rate of 33 ml/h during the surgical procedure until the maximum of 3 h

Placebo

Pedro Rotava, MD

The purpose of this study is to evaluate the effects of MgSO4 administration on the pharmacodynamics of rocuronium in patients with 60 or more years of age.

Magnesium Sulphate and Rocuronium in Patients Over 60

Effects of Magnesium Sulphate on the Pharmacodynamics of Rocuronium in Patients 60 Years or Older: Randomised and Double-Blind Study

Time from the start of injection of rocuronium until TOF ratio 0.9

Time from the start of injection of rocuronium until 95% depression of the first twitch (T1) of the TOF

Time from the start of injection of rocuronium until T1 of the TOF had recovered to 25% of the initial T1 value

Time between 25% and 75% recovery of the initial T1 value

Time between 25% recovery of the initial T1 value and a TOF ratio of 0.9

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Magnesium Sulphate and Rocuronium in Patients Over 60	NCT01804205	Head and Neck C...	Magnesium Sulfa... Placebo	60 Years -	Instituto Nacional de Cancer, Brazil
Magnesium Sulphate and Rocuronium in Patients Over 60	NCT01804205	Head and Neck C...	Magnesium Sulfa... Placebo	60 Years -	Instituto Nacional de Cancer, Brazil

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Spots Global Cancer Trial Database for onset time

Every month we try and update this database with for onset time cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for onset time cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.