Skin and Connective Tissue Diseases

Symptoms and General Pathology

All Conditions

Alopecia

Alopecia Areata

Hypotrichosis

Hair Diseases

Skin Diseases

Pathological Conditions, Anatomical

Antihypertensive Agents

Vasodilator Agents

All Drugs and Chemicals

Minoxidil

Patients receive oral minoxidil at a dose of 0.01 (\<40kg) and 0.02 (≥40kg) mg/kg/day for 8 months

Patient receive placebo for 4 months followed by oral minoxidil for 4 months

minoxidil at a dose of 0.01 (\<40kg) and 0.02 (≥40kg) mg/kg/day

Oral Minoxidil

Placebo

Alina Markova, MD

Danielle Friedman, MD

This study will test whether minoxidil taken by mouth (oral minoxidil) can improve hair loss caused by cancer treatment in children and young adults. In addition, the researchers will test the safety of oral minoxidil, and see if the study drug causes few or mild side effects in participants. Other purposes of this study include looking at whether participants are able to follow their study drug dosing schedules, and how oral minoxidil affects participants' quality of life.

A Study of Oral Minoxidil to Treat Hair Loss in Children, Teens, and Young Adults Who Are Cancer Survivors

A Pilot Study of Oral Minoxidil for the Treatment of Persistent Hair Loss in Pediatric, Adolescent, and Young Adult Cancer Survivors

Memorial Sloan Kettering Cancer Center supports the international committee of medical journal editors (ICMJE) and the ethical obligation of responsible sharing of data from clinical trials. The protocol summary, a statistical summary, and informed consent form will be made available on clinicaltrials.gov when required as a condition of Federal awards, other agreements supporting the research and/or as otherwise required. Requests for deidentified individual participant data can be made beginning 12 months after publication and for up to 36 months post publication. Deidentified individual participant data reported in the manuscript will be shared under the terms of a Data Use Agreement and may only be used for approved proposals. Requests may be made to: crdatashare@mskcc.org.

as assessed by Hairmetrix allows trichoscopy (dermoscopic imaging of the scalp and hair) in real time. It requires no special scalp or hair preparation and allows fully automated unclipped analysis, producing measurements.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
A Study of Oral Minoxidil to Treat Hair Loss in Children, Teens, and Young Adults Who Are Cancer Survivors	NCT05778825	Survivors of Ch... Alopecia	Oral Minoxidil Placebo	6 Years - 18 Years	Memorial Sloan Kettering Cancer Center
A Study of Oral Minoxidil to Treat Hair Loss in Children, Teens, and Young Adults Who Are Cancer Survivors	NCT05778825	Survivors of Ch... Alopecia	Oral Minoxidil Placebo	6 Years - 18 Years	Memorial Sloan Kettering Cancer Center

Spots Global Cancer Trial Database for oral minoxidil