Neoplasms

Urinary Tract, Sexual Organs, and Pregnancy Conditions

All Conditions

Symptoms and General Pathology

Prostatic Neoplasms

Pain

Genital Neoplasms, Male

Urogenital Neoplasms

Genital Diseases

Genital Diseases, Male

Urogenital Diseases

Prostatic Diseases

Male Urogenital Diseases

In Group 1, Patients detected with a PI-RADS (Prostate Imaging Reporting and Data System) ≥3 lesion on MpMRI underwent MpMRI-guided MRI- US fusion prostate biopsy. In this fusion biopsy, 12 core standard biopsy and 2-4 cores of biopsies from lesions defined on multiparametric prostate MRI

In Group 2, patients who had no suspected lesions or had a PI-RADS \<3 lesion on MpMRI underwent Transrectal ultrasound guided 12 core prostate biopsy (SPB).

TRUS-guided SPB was performed by obtaining 12 core samples in each patient. 6 cores from left and right. the cores labeled as, apex, mid, base, apex far lateral, mid far lateral and base far lateral

Standard transrectal 12 core biopsy

FPB was performed by obtaining 10-12 core samples in each patient, followed by the acquisition of 2-4 core samples for each suspected lesion detected on MpMRI (combined biopsy)

MRI- US fusion prostate biopsy (FPB)

Abdullah T Demirtaş, MD

The aim of this study was to compare the pain levels in transrectal ultrasound (TRUS)-guided standard 12-core prostate biopsy (SPB) and multiparametric prostate magnetic resonance imaging (MpMRI)-guided fusion prostate biopsy (FPB).

The study included patients that underwent prostate biopsy under local anesthesia (intrarectal 2% lidocaine gel + periprostatic nerve block) due to suspected prostate cancer. Patients detected with a Prostate Imaging Reporting and Data System score (PIRADS) ≥3 lesion on MpMRI underwent MpMRI-guided FPB (Group I) and the patients who had no suspected lesions or had a PI-RADS \<3 lesion on MpMRI underwent TRUS-guided SPB (Group II). Pain assessment was performed using Visual Analog Scale (VAS) 5 min after the procedure. Following the procedure, the patients were asked to indicate the most painful biopsy step among the three steps (1: insertion of the probe into the rectum, 2: probe manipulation, 3: the piercing of the biopsy needle).

pain levels after standard transrectal prostate 12 core biopsy and MRI -US fusion prostate biopsy were detected and compared in 2 groups.

Comparison of Pain Levels in Fusion Prostate Biopsy and Standard TRUS-Guided Biopsy

to ask patients most painful step of procedure that verbally defined them before biopsy as 1: insertion of the probe into the rectum, 2: probe manipulation, and 3: the piercing of the biopsy needle

pain assessment was performed using Visual Analogue Scale (VAS)

TC Erciyes University

Abdullah Demirtas, Md, Assoc. Prof.

Nervous System Diseases

Rare Diseases

Pain, Procedural

Breakthrough Pain

Neurologic Manifestations

Oculocerebral Syndrome With Hypopigmentation

Mobilization

Positioning

Personal Hygiene Care

Bladder catheterization

Wound care

Subcutaneous drugs administration

Giuseppe Casale, Medicine

This study aims to assess self reported procedural pain compared with background pain and evaluate pain intensity differences across six standard procedures. Besides, rescue and preventive treatments used to control procedural pain will be examined.

Procedural Pain in Palliative Care: Prevalence, Intensity and Treatment

Procedural Pain in Palliative Care: Prevalence, Intensity and Treatment. A Prospective, Cross-sectional, Multicenter, National Study

Self reported pain intensity 10 minutes before the procedure, during the procedure (measured immediately after that the procedure is performed), 10 minutes after the procedure. Each item is scored 0-10 (0 = no pain; 10 = worst possible pain).

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Comparison of Pain Levels in Fusion Prostate Biopsy and Standard TRUS-Guided Biopsy	NCT03859804	Pain Due to Cer... Prostate Cancer Biopsy	Standard transr... MRI- US fusion ...	50 Years - 75 Years	TC Erciyes University
Procedural Pain in Palliative Care: Prevalence, Intensity and Treatment	NCT02437929	Breakthrough Pa... Pain Due to Cer... Pain Cancer Terminal Diseas...	Mobilization Positioning Personal Hygien... Bladder cathete... Wound care Subcutaneous dr...	18 Years -	Antea Foundation
Procedural Pain in Palliative Care: Prevalence, Intensity and Treatment	NCT02437929	Breakthrough Pa... Pain Due to Cer... Pain Cancer Terminal Diseas...	Mobilization Positioning Personal Hygien... Bladder cathete... Wound care Subcutaneous dr...	18 Years -	Antea Foundation
Comparison of Pain Levels in Fusion Prostate Biopsy and Standard TRUS-Guided Biopsy	NCT03859804	Pain Due to Cer... Prostate Cancer Biopsy	Standard transr... MRI- US fusion ...	50 Years - 75 Years	TC Erciyes University
Procedural Pain in Palliative Care: Prevalence, Intensity and Treatment	NCT02437929	Breakthrough Pa... Pain Due to Cer... Pain Cancer Terminal Diseas...	Mobilization Positioning Personal Hygien... Bladder cathete... Wound care Subcutaneous dr...	18 Years -	Antea Foundation
Comparison of Pain Levels in Fusion Prostate Biopsy and Standard TRUS-Guided Biopsy	NCT03859804	Pain Due to Cer... Prostate Cancer Biopsy	Standard transr... MRI- US fusion ...	50 Years - 75 Years	TC Erciyes University

Spots Global Cancer Trial Database for pain due to certain specified procedures