Neoplasms

All Conditions

Perivascular Epithelioid Cell Neoplasms

Neoplasms, Connective and Soft Tissue

Neoplasms by Histologic Type

Gabriel MALOUF, MD, PhD

Agathe BOURGMAYER, MD

Thomas RYCKEWAERT, MD

Perivascular epithelioid cell tumors are rare and characterized by the expression of myomelanocytic markers. They belong to a complex tumor family that includes angiomyolipomas, lymphangioleiomyomatosis and other soft-tissue tumors. Given their rarity, the natural history of pecomas is not yet understood, and a comprehensive classification that integrates clinical, pathological and molecular features has not been achieved as of today.

This study is a national multicenter retrospective study to better understand the natural history of PEComas, excluding lymphangioleiomyomatosis and classic triphasic angiomyolipomas.

The primary purpose is the identification of prognostic markers impacting the relapse. Secondaries purposes are to identify prognostic markers impacting the overall survival and to have a better understanding of natural history

PEComas: Natural History and Prognostic Factors

National Multicenter Retrospective Study: PEComas: Natural History and Prognostic

University Hospital, Strasbourg, France

Blood and Lymph Conditions

Immune System Diseases

Rare Diseases

Lymphangioleiomyomatosis

Angiomyolipoma

Agathe Bourgmayer, MD

Céline Charon-Barra, MD

Christine Chevreau, MD

François Bertucci, MD

Loic Chaigneau, MD

Nelly Firmin, MD

François SEVERAC, Statistician

Youenn DAVIDSON, Statistician

Perivascular epithelioid cell tumors (PEComas) are rare and are characterized by the expression of myomelanocytic markers. They are a complex family that includes angiomyolipomas, lymphangioleiomyomatoses and other soft tissue and visceral tumors. Due to the low prevalence of these tumors, the natural history is unclear; furthermore, a molecular classification integrating clinical, pathological and molecular parameters has not been described to date.

Molecular Characterization of Perivascular Epithelioid Cell Tumors

Study title	NCT ID	Conditions	Eligibility	Organization
PEComas: Natural History and Prognostic Factors	NCT03916575	PEComas	1 Year -	University Hospital, Strasbourg, France
Molecular Characterization of Perivascular Epithelioid Cell Tumors	NCT05617105	Perivascular Ep...	1 Year -	University Hospital, Strasbourg, France
Molecular Characterization of Perivascular Epithelioid Cell Tumors	NCT05617105	Perivascular Ep...	1 Year -	University Hospital, Strasbourg, France

Spots Global Cancer Trial Database for pecomas

Every month we try and update this database with for pecomas cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for pecomas

Every month we try and update this database with for pecomas cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for pecomas cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.