Neoplasms

Gland and Hormone Related Diseases

All Conditions

Thyroid Neoplasms

Thyroid Diseases

Carcinoma

Carcinoma, Papillary

Endocrine System Diseases

Endocrine Gland Neoplasms

Head and Neck Neoplasms

Neoplasms, Glandular and Epithelial

Neoplasms by Histologic Type

Neoplasms, Squamous Cell

Participants with papillary microcarcinoma (PTMC) who have elected to proceed with thyroidectomy rather than an observational management approach will be considered as potential candidates for this trial.

Percutaneous Laser Ablation / PLA will be carried out in a single session by advancing one 21-gauge spinal needle into the target lesions under real time US guidance.

Percutaneous Laser Ablation (PLA)

R. Michael Tuttle, MD

Stephen Solomon, MD

The purpose of this study is to explore whether percutaneous laser ablation (PLA) is a safe and effective alternative to removing papillary thyroid microcarcinoma (PTMC) with surgery.

Laser Ablation of Papillary Thyroid Microcarcinoma

Pilot Study to Evaluate the Safety and Efficacy of Percutaneous Laser Ablation of Thyroid Papillary Microcarcinoma

Memorial Sloan Kettering Cancer Center supports the international committee of medical journal editors (ICMJE) and the ethical obligation of responsible sharing of data from clinical trials. The protocol summary, a statistical summary, and informed consent form will be made available on clinicaltrials.gov when required as a condition of Federal awards, other agreements supporting the research and/or as otherwise required. Requests for deidentified individual participant data can be made beginning 12 months after publication and for up to 36 months post publication. Deidentified individual participant data reported in the manuscript will be shared under the terms of a Data Use Agreement and may only be used for approved proposals. Requests may be made to: crdatashare@mskcc.org.

Complete thermal ablation of the targeted PTMC (T1aN0M0) as determined by histological examination of thyroid tissue obtained by either thyroid lobectomy or total thyroidectomy 6 months after PLA.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Laser Ablation of Papillary Thyroid Microcarcinoma	NCT04623801	Papillary Thyro... Thyroid Thyroid Cancer	Percutaneous La...	18 Years -	Memorial Sloan Kettering Cancer Center
Laser Ablation of Papillary Thyroid Microcarcinoma	NCT04623801	Papillary Thyro... Thyroid Thyroid Cancer	Percutaneous La...	18 Years -	Memorial Sloan Kettering Cancer Center
Laser Ablation of Papillary Thyroid Microcarcinoma	NCT04623801	Papillary Thyro... Thyroid Thyroid Cancer	Percutaneous La...	18 Years -	Memorial Sloan Kettering Cancer Center

Spots Global Cancer Trial Database for percutaneous laser ablation (pla)