Symptoms and General Pathology

All Conditions

Pain

patients will receive US assisted caudal epidural pulsed radiofrequency and followed up to 8 weeks

US assisted caudal epidural pulsed radiofrequency

Our primary goal will be to investigate the analgesic efficacy of ultrasound (US)-assisted caudal epidural PRF (pulsed radiofrequency)( stimulation in patients with perineal or anal pain cancer patients using (visual analog scale (VAS) scores from 0 to 10 at the baseline (pretreatment), two, four, and eight weeks; secondary outcomes will be the effects on opioid use and total opioid use in the 24 h, quality of life, patient satisfaction and opioid and intervention related side effects.

Efficacy of Ultrasound-assisted Caudal Epidural Pulsed Radiofrequency for Anal Pain in Cancer Patients,

Efficacy of Ultrasound-assisted Caudal Epidural Pulsed Radiofrequency for Anal and Perineal Pain in Cancer Patients, a Prospective Randomized Clinical Study

Our primary goal will be to investigate the analgesic efficacy of ultrasound-assisted caudal epidural PRF stimulation in patients with perineal or anal pain cancer patients using VAS scores from 0 to 10 at the baseline (pretreatment), two, four, and eight weeks

Assiut University

associate professor of anesthesia, intensive care and pain management

Nervous System Diseases

Neoplasms

Skin and Connective Tissue Diseases

Rare Diseases

Neuralgia

Ganglion Cysts

Pudendal Neuralgia

Synovial Cyst

Cysts

Mucinoses

Connective Tissue Diseases

Chronic Graft Versus Host Disease

All Drugs and Chemicals

Analgesics

Botulinum Toxins

Botulinum Toxins, Type A

abobotulinumtoxinA

One injection of botulinum toxin type A in the ganglion Impar in patients with chronic proctalgia

Botox

Jean-Jacques LABAT, Dr

The main objective is to evaluate the analgesic efficacy of botulinum toxin type A in refractory chronic proctalgia one month after a bilateral injection of 50 units of Botox ® in the ganglion Impar (total dose = 100 units)

Analgesic Effect of an Injection of Botulinum Toxin Type A in the Ganglion Impar in Patients With Chronic Proctalgia

Prospective Multicenter Pilot Study Evaluating the Analgesic Effect of an Injection of Botulinum Toxin Type A in the Ganglion Impar in Patients With Chronic Proctalgia According to the Criteria of Rome III

The main objective is to evaluate the analgesic efficacy of botulinum toxin type A in refractory chronic proctalgia one month after a bilateral injection of 50 units of Botox ® in the ganglion Impar (total dose = 100 units) by calculating the main score (SP).

Nantes University Hospital

Urinary Tract, Sexual Organs, and Pregnancy Conditions

Uterine Cervical Neoplasms

Cancer Pain

Pelvic Pain

Endometrial Neoplasms

Uterine Neoplasms

Genital Neoplasms, Female

Urogenital Neoplasms

Uterine Cervical Diseases

Uterine Diseases

Genital Diseases, Female

Genital Diseases

Urogenital Diseases

Female Urogenital Diseases

Pregnancy Complications

Female Urogenital Diseases and Pregnancy Complications

Neurologic Manifestations

Anti-Arrhythmia Agents

Channel Blockers

Central Nervous System Depressants

Anti-Infective Agents

Lidocaine

Ethanol

Device: C-arm fluoroscopic device Drug: lidocaine + alcohol

this procedure uses a transdiscal approach at the level of the L5-S1 vertebrae by injecting 5 ml of 1% lidocaine + 10 ml of 96% alcohol and confirmed by C-arm.

Superior Hypogastric Plexus Block

this procedure uses a trans-sacrococcygeal approach by injecting 4 ml of 1% lidocaine + 6 ml of 96% alcohol and confirmed by C-arm.

Ganglion Impar Block

Ristiawan Muji Laksono, MD,FIPP

This study compared the efficacy and safety of superior hypogastric plexus block and ganglion impar block procedures on the management of pelvic and perineal cancer pain in patients with cervical and endometrial cancer

Superior hypogastric plexus block is a commonly used method for the management of pelvic and perineal pain due to cancer, this procedure uses a transdiscal approach at the level of the L5-S1 vertebrae by injecting 5 ml of 1% lidocaine + 10 ml of 96% alcohol and confirmed by C-arm.

Compared with the ganglion impar block procedure using a trans-sacrococcygeal approach by injecting 4 ml of 1% lidocaine + 6 ml of 96% alcohol and confirmed by C-arm. The aim of this study was to compare the efficacy and safety of the ganglion impar block procedure against the superior hypogastric plexus block which is commonly used in the management of pelvic and perineal pain due to cervical and endometrial cancer.

Patients were assigned to two groups.

Group 1: Patients with pelvic floor pain due to cervical and endometrial cancer who were treated with superior hypogastric plexus block.

Group 2: Patients with pelvic floor pain due to cervical and endometrial cancer who were given ganglion impar block.

Participant and Investigator masking:

The random order of the groups will be written on paper and hidden by using a sealed envelope with consecutive numbers. This envelope will be retained by personnel who are not involved in the care or evaluation of the patient, or the analysis of the data.

During the action, doctors and nurses are prohibited from communicating with participants regarding the actions given.

Outcomes assessor masking:

All data collection will be carried out by residents as research assistants who are trained for data collection. The assistant was not told what intervention was given to the patient, data collection was done directly by asking the patient without looking at the patient's status. The data that has been collected will be entered and processed by personnel outside the research team to ensure blinding.

Hypogastric Plexus Block and Ganglion Impar Block for Cervical and Endometrial Cancer Pain Management

Hypogastric Plexus Block and Ganglion Impar Block for Cervical and Endometrial Cancer Pain Management: A Randomized Controlled Trial of Efficacy and Safety

Used to measure pain relief with a value of 0-10 (0 = no pain, 1-3 = mild pain, 4-6 = moderate pain, 7-9 = severe pain, 10 = most severe pain). The average pain intensity felt by the patient in the last 1 week

The Oswestry Disability Index is a measuring tool to evaluate the quality of life and the level of disability. In this study, we will use the Indonesian adaptation version. in a journal published by Phedy et al showed that the Indonesian version of the ODI retains the reliability, validity, and psychometric characteristics of the original ODI.

There are 10 main questions with 6 assessment options from the lowest point of 0 and the highest point of 5.

0-20%: mild disability 21-40%: moderate disability, affecting activities can still be overcome 41-60%: severe disability, pain is a major problem and interferes with activities 61-80%: patients experience disturbances in major aspects of life requiring intervention 81-100%: the patient is confined to bed because of complaints

This is the dose that the patient takes regularly to relieve pain.

It is an unwanted effect due to the intervention given to the patient.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Efficacy of Ultrasound-assisted Caudal Epidural Pulsed Radiofrequency for Anal Pain in Cancer Patients,	NCT06008899	Perineal Pain	US assisted cau...	18 Years - 60 Years	Assiut University
Analgesic Effect of an Injection of Botulinum Toxin Type A in the Ganglion Impar in Patients With Chronic Proctalgia	NCT01331356	Proctalgia	Botox	18 Years -	Nantes University Hospital
Hypogastric Plexus Block and Ganglion Impar Block for Cervical and Endometrial Cancer Pain Management	NCT05427058	Cervical Cancer Endometrial Can...	Superior Hypoga... Ganglion Impar ...	18 Years -	University of Brawijaya
Hypogastric Plexus Block and Ganglion Impar Block for Cervical and Endometrial Cancer Pain Management	NCT05427058	Cervical Cancer Endometrial Can...	Superior Hypoga... Ganglion Impar ...	18 Years -	University of Brawijaya

Spots Global Cancer Trial Database for perineal pain