Neoplasms

Digestive System Diseases

Diseases and Abnormalities at or Before Birth

All Conditions

Symptoms and General Pathology

Rare Diseases

Choledochal Cyst

Cysts

Bile Duct Diseases

Biliary Tract Diseases

Gastrointestinal Diseases

Congenital Abnormalities

Digestive System Abnormalities

Bile Duct Cysts

To apply accelerated rehabilitation surgery to children with biliary dilatation during perioperative period

In this gruop,Children with cholangiectasia were given traditional perioperative treatment

Perioperative accelerated rehabilitation surgical measures

To provide traditional perioperative treatment for children with cholangiectasia

Traditional treatment

Xiaofeng Lv

Xiaofeng Lv, Master

Recently, with reference to the successful experience of accelerated rehabilitation surgery in the field of adult surgery, the investigators have conducted studies on ERAS in pediatric and even infant cholangiectasia surgery to discuss its feasibility and safety. The results showed that some items of ERAS could be safely applied in perioperative management of CBD, and could reduce traumatic stress and promote postoperative recovery. Therefore, the investigators assumed that the ERAS protocols could be safely applied in the treatment of CBD in children and even infants, reducing traumatic stress in children with CBD, promoting postoperative rehabilitation, reducing complications and hospitalization time, reducing hospitalization costs, and saving medical resources.

1. Optimize preoperative, intraoperative and postoperative perioperative management by learning from the successful experience of accelerated rehabilitation surgery model in other fields.

   For example: necessary and sufficient preoperative education of children and guardians; short fasting before surgery; oral carbohydrate at 2h before surgery; breast feeding at 4h before surgery (formula feeding at 6h before surgery); improved intestinal preparation; irregular placement of nasogastric tube; the use of general anesthesia plus epidural or sacral block anesthesia during surgery; attention to the whole process of heat preservation; strict control of infusion volume; and selection of minimally invasive hands Methods of operation; early postoperative activity, multi-mode analgesia, etc.
2. According to the pathophysiological characteristics of infants with cholangiectasia, several aspects were studied: minimally invasive surgery；promote gastrointestinal motor function recovery；develop principles and plans for early postoperative feeding；Rational placement of abdominal drainage tube; precise choice of anesthesia method, etc.

A RCT Study of ERAS in Infants With Choledochal Cyst

Application of Enhanced Recovery After Surgery During the Perioperative Period in Infants With Choledochal Cyst- a Multi-center Randomized Clinical Trial

To record the postoperative length of stay

To record the time of first exhaust and defecation and the time to return to full oral diet

To calculate the indwelling time of Gastrointestinal decompression tube after surgery

To calculate the indwelling time of Peritoneal drainage tube

To test the consentration of cortisol in blood

To test the consentration of IL-6 in blood

To test the consentration of IL-10 in blood

To test the consentration of CRP in blood

to observe postoperative pulmonary infection, infection of incision, baby, abdominal cavity infection and the occurrence of complications such as anastomotic fistula, cholangitis.

To investigate the "Parents satisfaction score scale" (minimum=0, maximun=100); the higher scores mean a better outcome.

To record the 30-day readmission rate after surgery

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
A RCT Study of ERAS in Infants With Choledochal Cyst	NCT05770739	Enhanced Recove... Infant ALL Cholangiectasis	Perioperative a... Traditional tre...	1 Day - 12 Months	Nanjing Children's Hospital
A RCT Study of ERAS in Infants With Choledochal Cyst	NCT05770739	Enhanced Recove... Infant ALL Cholangiectasis	Perioperative a... Traditional tre...	1 Day - 12 Months	Nanjing Children's Hospital
A RCT Study of ERAS in Infants With Choledochal Cyst	NCT05770739	Enhanced Recove... Infant ALL Cholangiectasis	Perioperative a... Traditional tre...	1 Day - 12 Months	Nanjing Children's Hospital

Spots Global Cancer Trial Database for perioperative accelerated rehabilitation surgical measures