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20 patients of verruca plana receiving daily topical Tazarotene 0.1% gel at night

20 patients with verruca plana will be treated with imiquimod cream 5% applied once daily at night

20 patients with verruca plana will be treated with topical 5- fluorouracil 5% cream applied once daily at night

20 patients with verruca plana will be treated with petroleum jelly once daily at night.

once daily topical application at night with a cotton tipped applicator on every lesion

Tazarotene 0.1% Gel,Top

Imiquimod cream 5% applied once daily at night with a cotton tipped applicator applied once daily.

5- Fluorouracil Cream 5% is applied once daily at night with a cotton tipped applicator

Fluorouracil Cream

Hagar Nofal, Dr.

Verruca plana is a common skin infection with worldwide distribution. Approximately 10% of general population is infected with flat warts and it represents up to 18 % of the patients seeking treatment for warts. Verruca plana is not merely an infectious disease but also affects the quality of patients' life. Verruca plana causes major cosmetic and social concerns. Lesions' persistence and recurrence cause frustrations and psychological distress which motivate patients to seek different treatment strategies. Verruca plana commonly affects the school aged children which augments its effect on the psychological and social development of children with stigmatization and bullying are great risks. The available treatment strategies neither ensured complete clearance of the disease nor were free of side effects. Frequently used physical removal methods are operator dependent and commonly lead to irritation, local inflammation, scars, dyspigmentation, and disfigurement. In this study we evaluate the efficacy and the safety of tazarotene gel 0.1% in the treatment of verruca plana compared to imiquimod or 5-fluorouracil

Patients will be assigned randomly into one of 4 groups as 1:1:1:1 using randomization.com with the seed number 7607

* Group (A): Patients will be treated with topical tazarotene gel 0.1%with a cotton tipped applicator on every lesion once daily at night.
* Group (B): Patients will be treated with topical 5- fluorouracil 5% cream applied once daily at night.
* Group (C): Patients will be treated with imiquimod cream 5% applied once daily at night.
* Group (D): Patients will be treated with petroleum jelly once daily at night.

Efficacy of Tazarotene in Treatment of Verruca Plana

Efficacy of Tazarotene Versus Topical 5-Fluorouracil, and Imiquimod in The Treatment of Verruca Plana

Complete clearance is defined by complete disappearance of the warts and return to normal skin markings

Spots Global Cancer Trial Database for petrolatum

Every month we try and update this database with for petrolatum cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for petrolatum

Every month we try and update this database with for petrolatum cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for petrolatum cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.