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Mobilization as soon as patients can, which is not limited on walking

Early mobilization

Lin Huang, MD

Henrik Kehlet, Professor, MD, DMSc

Rene H Petersen, Professor, MD, PhD

The main endpoint is physiological rehabilitation after VATS-L under early mobilization. The secondary endpoints are exploring the effect of early mobilization on postoperative physiology.

Investigators hypothesis that early mobilization is clearly advantaged to advance the physiological recovery.

Significance of Early Mobilization After VATS-L

Physiological Evidence for Early Mobilization in Thoracoscopic Lobectomy

FEV1 is the amount of air you can force from your lungs in one second. Participants will be examed via spirometer.

Oxygen saturation is the fraction of oxygen-saturated hemoglobin relative to total hemoglobin (unsaturated + saturated) in the blood. Participants will be tested via oximeter.

The numeric rating scale (NRS) ranging from 0 (no pain) to 10 (excruciating pain) is used to score postoperative pain.

Pneumothorax, subcutaneous emphysema, pneumonia, empyema, bleeding, pulmonary embolism, prolong air leakage, re-intervention, re-surgery and re-admission will be recording specifically.

Rigshospitalet, Denmark

Medical Doctor, Research fellow, PhD student

This group will be contacted to make an appointment for outpatient Occupational and Physical therapy. The therapist will determine the type, frequency and length of treatment. Follow up phone calls will be made to ensure appointments are made, kept and rescheduled as needed.

Patients randomized to this arm will receive contact information and a brochure outlining the services available within the supportive care program. The study coordinator will provide the information based on their results and assist the patient with contacting the program if desired.

OT and PT will be arranged for the subject and conducted in a manner as determined by the therapist.

Occupational and Physical Therapy

Mackenzi Pergolotti, PhD

The CARE Program is a randomized trial of a cancer rehabilitation program designed to help older cancer patients who have shown to have a loss of function.

This is a prospective, two-arm, single-center randomized controlled pilot trial of a cancer rehabilitation program for older adults, titled the 'CARE program,' which is designed to maintain and/or improve functional status and quality of life in older adults diagnosed with cancer. Adults aged 65 years and older with cancer will be screened with a Geriatric Assessment (GA) for eligibility. Although breast cancer patients will be eligible, this study will focus primarily on other types of cancers. Adults with at least one functional deficit --defined as impairment in ability to perform activities of daily living or instrumental activities of daily living, cognitive decline or balance -- will be randomized to either the intervention (CARE program) or to the control arm (Supportive care services information only). Both arms will receive a brochure about the supportive care program to provide patients who we've identified as having deficits with information about auxiliary services available and because the intent is to limit the difference between the groups. We hypothesize that patients who participate in the CARE program will maintain or improve functional status and quality of life when compared to supportive care services information only.

The CARE Program: CAncer REhabilitation Pilot Study for Older Adults

LCCC 1409: The CARE Program: CAncer REhabilitation Pilot Study for Older Adults

Compare the change in NEADL scores from baseline to 3 months between patients who receive the CARE program (intervention) and those in the control arm.

As measured by the Possibilities for Activity Scale (PActS)

As measured by the Blessed Memory Orientation Concentration test

To describe the feasibility of the CARE program by reporting enrollment and retention as defined by (1) percent eligible who agree to participate (2) percent in each group that completed follow-up measures at 2 and 3 months and (3) percent of patients in CARE program who go to 70% of appointments.

Intervention Group Only: As measured by the Berg Balance Scale

Intervention Group Only: As measured by the Disability of the Arm, Shoulder and Hand scale

Intervention Group Only: As measured by the Montreal Cognitive Assessment

Intervention Group Only: As measured by the Dynamic Gait Index

To evaluate the program a short interview will be completed with CARE team to determine what worked well, what didn't and suggested changes/improvements for CARE program after completion of project.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Significance of Early Mobilization After VATS-L	NCT04508270	Lung Neoplasm Physiology Exercise Lung Function Arterial Oxygen...	Early mobilizat...	18 Years -	Rigshospitalet, Denmark
The CARE Program: CAncer REhabilitation Pilot Study for Older Adults	NCT02306252	Cancer	Occupational an...	65 Years -	UNC Lineberger Comprehensive Cancer Center
Significance of Early Mobilization After VATS-L	NCT04508270	Lung Neoplasm Physiology Exercise Lung Function Arterial Oxygen...	Early mobilizat...	18 Years -	Rigshospitalet, Denmark

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Spots Global Cancer Trial Database for physiology

Every month we try and update this database with for physiology cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for physiology cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.