Diseases and Abnormalities at or Before Birth

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Neoplasms

Respiratory Tract (Lung and Bronchial) Diseases

Rare Diseases

Congenital Abnormalities

Mesothelioma

Mesothelioma, Malignant

Adenoma

Neoplasms, Glandular and Epithelial

Neoplasms by Histologic Type

Neoplasms, Mesothelial

Lung Neoplasms

Respiratory Tract Neoplasms

Thoracic Neoplasms

Pleural Neoplasms

Lung Diseases

Respiratory Tract Diseases

Malignant Mesothelioma

Central Nervous System Depressants

All Drugs and Chemicals

Anesthetics

All patient with suspected malignant pleural mesothelioma requiring surgical biopsy after validation in oncologic multidisciplinary board will be included. During a standardized routine procedure of pleural biopsy by mean of general anesthesia and video thoracoscopic approach, 3 - 5 biopsies are realized. During this procedure, blood samples are collected and a piece of biopsy will be used for the constitution of a specific bio collection in the CRB (centre de ressources biologiques).

PLEURAL BIOCOLLECTION OF MALIGNANT PLEURAL MESOTHELIOMA

Jean-Michel MAURY, MD

Jean Michel MAURY

Malignant pleural mesothelioma (MPM) is a rare pleural cancer, which could be primary or secondary to an asbestos exposure. To enhance our knowledge of this rare disease, an exploration of genetic and tumor mechanism is mandatory. One of the principal difficulty is to harvest sufficient tumour pieces to perform multi-omics analysis. The goal of the SCITH-MESO study is to harvest larges pieces of tumour during a routine surgical procedure of MPM diagnosis by mean of pleural biopsies during VATS surgery. Operating samples will increase a tissue bank collection (CRB).

pleural samples of malignant pleural mesothelioma

Molecular, Pathologic Intra Tumoral Heterogeneity in Malignant Pleural Mesothelioma

For patients with MPM, blood samples are collected and a piece of biopsy will be used for the constitution of a specific bio collection in the CRB (centre de ressources biologiques).

Hospices Civils de Lyon

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Molecular, Pathologic Intra Tumoral Heterogeneity in Malignant Pleural Mesothelioma	NCT04823741	Mesothelioma, M... Gene Abnormalit... Pleural Mesothe...	PLEURAL BIOCOLL...	18 Years - 95 Years	Hospices Civils de Lyon
Molecular, Pathologic Intra Tumoral Heterogeneity in Malignant Pleural Mesothelioma	NCT04823741	Mesothelioma, M... Gene Abnormalit... Pleural Mesothe...	PLEURAL BIOCOLL...	18 Years - 95 Years	Hospices Civils de Lyon

Spots Global Cancer Trial Database for pleural biocollection of malignant pleural mesothelioma