Heart and Blood Diseases

All Conditions

Symptoms and General Pathology

Diseases and Abnormalities at or Before Birth

Neoplasms

Digestive System Diseases

Respiratory Tract (Lung and Bronchial) Diseases

Nutritional and Metabolic Diseases

Nervous System Diseases

Urinary Tract, Sexual Organs, and Pregnancy Conditions

Gland and Hormone Related Diseases

Rare Diseases

Hypertension

Syndrome

Congenital Abnormalities

Liver Neoplasms

Hypertension, Pulmonary

Insulin Resistance

Hepatic Encephalopathy

Hypoglycemia

Vascular Malformations

Hyperandrogenism

Hyperinsulinism

Hyperammonemia

Hepatopulmonary Syndrome

Hypoglycemic Agents

All Drugs and Chemicals

Hematinics

Insulin

Insulin, Globin Zinc

Liver Extracts

Consist in spontaneous, surgical or interventional closure of the shunt. Depending on context, surgical intervention may also be transplantation.

Shunt Closure

Valérie A Mc Lin, Prof. Dr. med.

Congenital Portosystemic Shunt (CPSS) is a rare condition important by the multiplicity and severity of associated complications.

CPSS is venous anomaly in which blood coming from the intestines only partially passes through the liver.

This leads to the accumulation of potentially toxic factors that cause systemic effects.

Complications vary among the individuals, and currently, it is challenging to predict which individuals will develop severe complications.

The IRCPSS registry is established with the aim of centralizing detailed clinical follow-up and biological information from participants around the world who suffer from Congenital Portosystemic Shunt (CPSS). A multidisciplinary consortium of experts is collaborating to enhance our understanding of the prevalence, natural history, individual risks, and physiopathology of the disease through the IRCPSS registry.

International Registry of Congenital Portosystemic Shunt (IRCPSS)

International Registry of Congenital Portosystemic Shunts (IRCPSS) - A Multi-centre, Retrospective and Prospective Registry of Neonates, Children and Adults With Congenital Portosystemic Shunts

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
International Registry of Congenital Portosystemic Shunt (IRCPSS)	NCT06041906	Congenital Port...	Shunt Closure	1 Day -	University Hospital, Geneva
International Registry of Congenital Portosystemic Shunt (IRCPSS)	NCT06041906	Congenital Port...	Shunt Closure	1 Day -	University Hospital, Geneva

Spots Global Cancer Trial Database for portasystemic