Symptoms and General Pathology

All Conditions

Neoplasms

Urinary Tract, Sexual Organs, and Pregnancy Conditions

Gland and Hormone Related Diseases

Rare Diseases

Recurrence

Ovarian Neoplasms

Carcinoma, Ovarian Epithelial

Fallopian Tube Neoplasms

Adnexal Diseases

Genital Diseases, Female

Genital Diseases

Urogenital Diseases

Female Urogenital Diseases

Pregnancy Complications

Female Urogenital Diseases and Pregnancy Complications

Genital Neoplasms, Female

Urogenital Neoplasms

Fallopian Tube Diseases

Ovarian Cancer

Ovarian Epithelial Cancer

Fallopian Tube Cancer

D4064A

Scott Holden, M.D.

This is a Phase I, multicenter, open-label, dose-escalation study of single-agent D4064A administered by IV infusion to patients with recurrent or persistent epithelial ovarian cancer (EOC), primary peritoneal cancer (PPC), and fallopian tube cancer (FTC) who have previously received a platinum-containing regimen. The study will enroll up to 56 patients at up to six investigative sites in the United States.

A Study of D4064A Administered to Patients With Recurrent or Persistent Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer

A Phase I, Open-Label, Dose-Escalation Study of the Safety and Pharmacokinetics of D4064A Administered Intravenously to Patients With Recurrent or Persistent Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer After a Platinum-Containing Regimen

Genentech, Inc.

Clinical Trials Posting Group

Respiratory Tract (Lung and Bronchial) Diseases

Lung Neoplasms

Respiratory Tract Neoplasms

Thoracic Neoplasms

Lung Diseases

Respiratory Tract Diseases

To evaluate if continuous positive airway pressure(CPAP) on the lung undergoing lobectomy can decrease the inflammatory response PPC (postoperative pulmonary complications).

To evaluate if continuous positive airway pressure (CPAP) on the lung undergoing lobectomy can decrease the inflammatory response and PPC.

CPAP (Continuous airway pressure)

Lluis Gallart, PhD

This is a randomized placebo-controlled trial studying the effects of intraoperative continuous airway pressure (CPAP) on the inflammatory response of the lung with cancer undergoing lobectomy.

Pulmonary lobectomy induces an inflammatory response of this lung caused by intraoperative atelectasis and re-expansion. This inflammatory response can be attenuated with treatment, also decreasing postoperative pulmonary complications (PPC). Thus, avoiding complete atelectasis with partial insufflation of the lung during surgery could be useful to decrease inflammatory response and PPC.

Effects of Intraoperative Continuous Airway Pressure (CPAP) on the Inflammatory Response to One-lung Ventilation

Effects of Intraoperative Continuous Airway Pressure (CPAP) on the Inflammatory Response of the Lung With Cancer Undergoing Lobectomy. A Randomised Placebo-controlled Trial

Alveolar and plasmatic cytokines measured before and after atelectasis and re-expansion.

Alveolar MICA I (major histocompatibility complex (MHC) class I chain related genes) expression measured at the same control times.

Postoperative distribution of well-aerated, non aerated or poorly aerated lung volumes.

Parc de Salut Mar

Infections

Digestive System Diseases

Communicable Diseases

Necrosis

Pancreatic Pseudocyst

Disease Attributes

Cysts

Pancreatic Cyst

Pancreatic Diseases

Gastrointestinal Diseases

By using a convex type ultrasonic endoscope to form a fistula by gastrointestinal puncture, to perform various drainage.

EUS-guided fistulization AXIOS

To detect information of Adverse Events and Device Malfunctions under real world medical condition in Japan.

Hot AXIOS System Japan Post Market Survey

A Post Market Survey to Detect Information of Adverse Events and Device Malfunctions of AXIOS Stent and Electrocautery Enhanced Delivery System Under Real World Medical Condition in Japan

AXIOS stent is placed in an appropriate position using the delivery system.

AXIOS stent stays at the position where it was implanted during the implant procedure.

The lumen of AXIOS stent is patent, and it can be used for drainage etc.

AXIOS stent can be removed using standard endoscopic snares or forceps.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
A Study of D4064A Administered to Patients With Recurrent or Persistent Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer	NCT00753480	Fallopian Tube ... Ovarian Cancer Peritoneal Canc...	D4064A	18 Years -	Genentech, Inc.
Effects of Intraoperative Continuous Airway Pressure (CPAP) on the Inflammatory Response to One-lung Ventilation	NCT01368601	Lung Cancer	CPAP (Continuou...	18 Years - 80 Years	Parc de Salut Mar
A Study of D4064A Administered to Patients With Recurrent or Persistent Epithelial Ovarian, Primary Peritoneal, or Fallopian Tube Cancer	NCT00753480	Fallopian Tube ... Ovarian Cancer Peritoneal Canc...	D4064A	18 Years -	Genentech, Inc.
Effects of Intraoperative Continuous Airway Pressure (CPAP) on the Inflammatory Response to One-lung Ventilation	NCT01368601	Lung Cancer	CPAP (Continuou...	18 Years - 80 Years	Parc de Salut Mar
Effects of Intraoperative Continuous Airway Pressure (CPAP) on the Inflammatory Response to One-lung Ventilation	NCT01368601	Lung Cancer	CPAP (Continuou...	18 Years - 80 Years	Parc de Salut Mar
Hot AXIOS System Japan Post Market Survey	NCT03797209	Pancreatic Pseu... Pancreatic Pseu... Walled Off Necr... Walled Off Necr...	EUS-guided fist...	-	Boston Scientific Japan K.K.

Spots Global Cancer Trial Database for ppc

Every month we try and update this database with for ppc cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for ppc

Every month we try and update this database with for ppc cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for ppc cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.