Neoplasms

Digestive System Diseases

All Conditions

Rare Diseases

Stomach Neoplasms

Stomach Cancer

Antineoplastic Agents

All Drugs and Chemicals

Fluorouracil

Cisplatin

Immunomodulating Agents

Precision Cells combined with Chemotherapy treatment: Chemotherapy:

once a week with a total of six times before 60 days prior to the start of drawing blood. Precision Cells：once per 3 weeks with a total of three periods.

Chemotherapy:

once a week with a total of six times before 60 days prior to the start of drawing blood.

Cisplatin：60mg/m2，5-FU：500mg/m2,Physiological saline 100ml:IV (in the vein) once a week with a total of six times.

Chemotherapy

DC cell suspension (1×10\*7 DC+physiological saline + 0.25% human bloodalbumin)1ml for each infusion, subcutaneous injection for each infusion, 3 cycles, each cycle received two infusions on day 19, 20; 40, 41; 61, 62. Precision cells suspension (1-6×109 Precision cells + physiological saline + 0.25% human bloodalbumin) 300ml for each infusion, IV (in the vein) for each infusion, 3 cycles, each cycle received one infusions on day 21, 42, 63.

Precision Cells

Naiyan Han

Objectives:

To evaluate the safety and effectiveness of cell therapy using Precision Cell Immunotherapy to treat Advanced Gastric Cancer.

Eligibility:

Individuals greater than or equal to 18 years of age and less than or equal to 65 years of age who have been diagnosed with Advanced Gastric Cancer.

A total of 40 patients may be enrolled over a period of 1-2 years.

Precision Cell Immunotherapy Combined With Chemotherapy in Advanced Gastric Cancer

Clinical Study Using Precision Cell Immunotherapy Combined With Chemotherapy in Advanced Gastric Cancer

Shanghai International Medical Center

Liver Neoplasms

Gastrointestinal Neoplasms

Digestive System Neoplasms

Gastrointestinal Diseases

Liver Diseases

Hematinics

Chlorotrianisene

Liver Extracts

Ethiodized Oil

Precision Cells combined with Transcatheter Arterial Chemoembolization:

Transcatheter Arterial Chemoembolization:

patients will receive MMC,EADM hepatic arterial infusion,6 cycles. Precision Cells：After accepting concurrent TACE treatment,patients will receive 3 cycles of Precision Cells treatment

patients will receive MMC,EADM hepatic arterial infusion,6 cycles.

Lipiodol 10-20ml,MMC 8～10mg,EADM20～40mg.According to tumor area of maximum diameter,0.1～0.2ml/cm2 Hepatic arterial infusion.

TACE

DC cell suspension (1×107 DC+ physiological saline + 0.25% human bloodalbumin) 1ml for each infusion, subcutaneous injection for each infusion 3 cycles, each cycle received two infusions on day 19, 20; 40, 41; 61, 62. Precision cells suspension (1-6×109 Precision cells + physiological saline + 0.25% human bloodalbumin) 300ml for each infusion, IV (in the vein) for each infusion 3 cycles, each cycle received one infusions on day 21, 42, 63.

Objectives:

To evaluate the safety and effectiveness of cell therapy using Precision Cells Combined With TACE in Advanced Liver Cancer.

Eligibility:

Individuals greater than or equal to 18 years of age and less than or equal to 65 years of age who have been diagnosed with Advanced Liver Cancer.

Precision Cell Immunotherapy Combined With TACE in Advanced Liver Cancer

Clinical Study Using Precision Cell Immunotherapy Combined With Transcatheter Arterial Chemoembolization in Advanced Liver Cancer

Transcatheter Arterial Chemoembolization:

patients will receive MMC,EADM hepatic arterial infusion,6 cycles. Precision Cells：After accepting concurrent TACE treatment,patients will receive 3 cycles of Precision Cells treatment

Lipiodol 10-20ml,MMC 8～10mg,EADM20～ 40mg.According to tumor area of maximum diameter,0.1～0.2ml/cm2 Hepatic arterial infusion.

DC cell suspension (1×107 DC+ physiological saline

+ 0.25% human bloodalbumin) 1ml for each infusion, subcutaneous injection for each infusion 3 cycles, each cycle received two infusions on day 19, 20; 40, 41; 61, 62. Precision Cell suspension (1-6×109 PMAT/PNAT + physiological saline + 0.25% human bloodalbumin) 300ml for each infusion, IV (in the vein) for each infusion 3 cycles, each cycle received one infusions on day 21, 42, 63.

Bi Wang

Bi Wan

Jiangtao Wang

Huajun Jin

Qijun Qian

To evaluate the safety and effectiveness of cell therapy using precision cells Combined With TACE in Advanced Liver Cancer.

Eligibility:

Individuals greater than or equal to 18 years of age and less than or equal to 65 years of age who have been diagnosed with Advanced Liver Cancer.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Precision Cell Immunotherapy Combined With Chemotherapy in Advanced Gastric Cancer	NCT02862561	Precision Cell ... Chemotherapy Advanced Malign...	Chemotherapy Precision Cells	18 Years - 65 Years	Shanghai International Medical Center
Precision Cell Immunotherapy Combined With Chemotherapy in Advanced Gastric Cancer	NCT02862561	Precision Cell ... Chemotherapy Advanced Malign...	Chemotherapy Precision Cells	18 Years - 65 Years	Shanghai International Medical Center
Precision Cell Immunotherapy Combined With TACE in Advanced Liver Cancer	NCT02862613	Precision Cells Transcatheter A... Advanced Liver ...	TACE Precision Cells	18 Years - 65 Years	Shanghai International Medical Center
Precision Cell Immunotherapy Combined With TACE in Advanced Liver Cancer	NCT02873442	Precision Cell ... Transcatheter A... Advanced Liver ...	TACE Precision Cells	18 Years - 65 Years	Ningbo Cancer Hospital

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