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prospective collection of surgical exudates (SEs) from patients who are hospitalized for post-operative recovery from esophagectomy or gastrectomy for gastroesophageal cancer

prospective collection of surgical exudates (SEs)

Keary Janet, BS

Stephanie Van Bebber, MSc.

Stephanie Van Bebber, MSc

Raymond Wadlow, MD

The purpose of this research is to collect surgical drain fluid and blood from patients who have undergone surgery for gastric or esophageal cancer, and to analyze the fluid and blood using a variety of laboratory techniques for molecular markers capable of predicting response to immunotherapy.

we will collect six to eight milliliters of fluid from surgical drains placed by the surgeon at the time of surgery to assist with wound healing. Samples will be collected at one and four to six days after surgery. One tube of blood will also be collected at both time points. The research will not include whole genome sequencing.

A Systems Approach to Immunotherapy Biomarker Identification Within the Postoperative Wound-Healing Microenvironment in Patients With Gastroesophageal Cancer

to establish a workflow for collection of SEs from patients affected by esophageal and gastric cancer undergoing surgical resection.

SEs will be collected and characterized using different assays with the goal of generating hypotheses of potential predictive and prognostic biomarkers to early (\<6 months) vs. late/non-recurrence of malignancy.

Spots Global Cancer Trial Database for prospective collection of surgical exudates (ses)