Symptoms and General Pathology

All Conditions

Digestive System Diseases

Behaviors and Mental Disorders

Rare Diseases

Fatigue

Rumination Syndrome

Rumination Disorder

It is planned to conduct the empowerment program online (zoom session). For this, to protect each individual's privacy, a quiet, bright and ventilated, spacious physical environment and technological elements such as computers, headphones, microphones and internet connection are needed. The empowerment program was planned as a total of 10 sessions, one session per week. In the program, goals and objectives have been established for each session. These aims and objectives will be shared with the participants before each session. The application time of each session is planned as an average of 90 minutes.

Empowerment program

Sinem Öcalan, Res. Asist.

Sinem Öcalan

This study aims to decrease cancer survivors' intrusive ruminative thoughts and cancer-related fatigue and increase their purposive ruminative thoughts and psychological resilience. In this context, an online (Zoom) 10-session empowerment program based on the literature will be implemented for cancer survivors.

From the time they were diagnosed with cancer, individuals struggle with ruminative thoughts about why they have this disease, whether they will get better during the treatment process, whether the disease will recur in the future, and cognitive, physical, and emotional fatigue, the cause of which cannot be fully explained. All these processes continue to negatively affect the lives of cancer survivors during the remission period. Studies show that when cancer survivors manage this stressful process well and learn effective coping methods, they can come out of it by developing their psychological resilience. Therefore, this study aimed to determine the effect of an empowerment program to be applied to cancer survivors' ruminative thoughts, cancer-related fatigue, and psychological resilience.

The hypotheses of this research are:

H 1-1: There is a difference between ruminative thinking scores at the end of the empowerment program applied to individuals with cancer in remission and in the follow-up measurement compared to the pre-program and control groups.

H 1-2: There is a difference between cancer-related fatigue scores at the end of the empowerment program applied to individuals with cancer in remission and in the follow-up measurement compared to the pre-program and control groups.

H 1-3: There is a difference between psychological resilience scores at the end of the empowerment program applied to individuals with cancer in remission and in the follow-up measurement compared to the pre-program and control groups.

Permission will be taken from Hacettepe University Oncology Hospital for the research. However, due to the pandemic conditions, to protect the health of both researchers and participants, group studies were moved to the online platform and the sessions were planned as online (zoom sessions). The sample size of the study was calculated with the G-Power 3.1 program. Since a similar study could not be found in the literature, it was determined that the sample should consist of 56 people, 28 in the intervention group and 28 in the control group, by calculating with .80 power and .05 error level, based on the medium effect size for the .25 variance analysis suggested by Cohen. However, it is foreseen that it would be appropriate to reach 10% more people (Total 62) of the total number calculated considering that there may be a loss of participants during the process and to be participants in the 31 intervention and 31 control group.

Empowerment Program for Cancer Survivors

The Effect of an Empowerment Program on Ruminative Thoughts, Fatigue, and Psychological Resilience of Cancer Survivors

It was developed by Cann et al. (2011). The 20-item scale has subscales to evaluate two forms of rumination, "intrusive" and "deliberate". The first ten items measure intrusive rumination, and the second ten items measure deliberate rumination. Each item in the scale is in a 4-point Likert type and is scored as 0 = never, 3 = often. There is no total score in this scale, but subscale scores reveal rumination scores. Scores on each subscale range from 0 to 30. High scores obtained from each sub-dimension of the scale indicate the existence of a ruminative thought tendency towards the said dimension.

It was developed by Okayama et al. in 2003. Consisting of 15 items, the scale has a 5-point Likert type ranging from 'no' (1) to 'too much' (5). It consists of three sub-dimensions: physical (items 1,2,3,6,9,12,15), emotional (items 5,8,11,14), cognitive (items 4,7,10,13). . The range of scores to be taken from the scale is between 0 and 28 points for the physical subscale, and 0 to 16 points for the emotional and cognitive subscale. Total fatigue is the sum of these subscale scores and the maximum total score is 60. The higher the total score, the more severe the fatigue is considered.

It was developed by Connor and Davidson (2003). The 25-item scale is in a 5-point Likert structure as 'not at all true' (0) and 'always true' (4). The scale consists of 3 subscales: 'Perseverance and Personal Efficiency' (15 items), 'Resistance to Negativity' (6 items) and 'Tension to Spirituality' (3 items). The lowest and highest values vary between 0-100, and the higher score obtained from the scale indicates greater psychological resilience.

Sinem Ocalan

Research assistant

Neoplasms

Skin and Connective Tissue Diseases

Breast Neoplasms

Quality of Life

Carl AK Borrebaeck, Professor

This study aims to define the association between psychological resilience and biomolecular signatures in cancer patients and to relate psychological resilience to prognosis, as this could potentially open up a novel avenue of therapeutic interventions, medical as well as psychosocial.

Individual patients differ in psychological response when receiving a cancer diagnosis. Given the same disease burden some patients master the situation well and others do experience a great deal of stress, depression and lowered quality of life. A patient's mental resistance after acquiring a threat, like a cancer diagnosis, called psychological resilience, is known to impact the outcome of the disease. Patients with high psychological resilience are likely to experience less stress reactions, and a better adaptation and management of the life threat and the demanding therapeutic interventions. How this phenomenon of mastering difficult situations is reflected also in bio-molecular processes is not much studied and how these have an impact on the cancer prognosis and the effectiveness of treatment is today not fully understood. However, there is evidence that expressing the emotions evoked is an important part of fighting cancer.

Our hypothesis is that patients displaying a high psychological resilience, according to a standardized method "The Connor-Davidson resilience scale" i.e. low stress reactions, low hopelessness and low fatigue, also present a specific pattern of biomolecular signatures in blood, represented by its epigenome, microRNA and proteomic patterns.

This project specifically aims to investigate if breast cancer patient´s psychological resilience can be coupled to bio-molecular parameters, using advanced "omics" and as a secondary aim, if it relates to prognosis and quality of life one year after diagnosis.

The study includes only women with newly diagnosed breast cancer

Sweden Cancerome Analysis Network - Breast (SCAN-B) Coupled to Psychological Resilience

The Molecular Fingerprint of Psychological Resilience - Implications for Diagnostic and Therapeutic Strategies

Upon publication, the relevant anonymized individual participant data will be shared.

Measured by CD-RISC and bimolecular techniques.

Measured by CD-RISC and study specific questionnaire based on the Swedish national cancer rehabilitation guidelines.

Measured by CD-RISC correlated to register data

Measured by CD-RISC and correlated to register data

Measured by SF-36 and correlated to register data

Vinnova

Mats Paulssons stiftelse, org. nr 802423-3150

Gunnar Nilsson's Cancer Foundation

CREATE Health Cancer Centre

Lund University

Breast Diseases

Skin Diseases

Patients will be trained by pecha kucha method using computer with powepoint presentation.

Education with pecha kucha method

Zülfünaz Özer, PhD

Gülcan Bahçecioğlu Turan, PhD

Zülfünaz Özer

This study was planned to investigate the effect of the training given to breast cancer patients receiving chemotherapy with pecha kucha method on posttraumatic growth and psychological resilience.

This study is a randomized controlled trial planned to investigate the effect of the training given to breast cancer patients receiving chemotherapy with the pecha kucha method on posttraumatic growth and psychological resilience.

This study is an experimental study with pre-test and post-test control groups

Female breast cancer patients receiving chemotherapy

Pecha Kucha Method Effects on Posttraumatic Growth and Psychological Resilience

Education Given to Breast Cancer Patients Receiving Chemotherapy With Pecha Kucha Method Effects on Posttraumatic Growth and Psychological Resilience

The 6-point Likert-type scale consists of 21 items and a 5-factor structure and is scored between 0-5. The total score that can be obtained from the scale varies between 0-105. The sub-dimensions of the scale are relationships with others, new possibilities, personal empowerment, spiritual change and appreciation of life. High scores on the scale indicate that posttraumatic growth is high.

The 6-point Likert-type scale consists of 21 items and a 5-factor structure and is scored between 0-5. The total score that can be obtained from the scale varies between 0-105. The sub-dimensions of the scale are relationships with others, new possibilities, personal empowerment, spiritual change and appreciation of life. High scores on the scale indicate that posttraumatic growth is high.

Before the training

1 month after the training

The scale measures the psychological resilience of individuals. It is a 5-point Likert-type, 6-item, self-report measurement tool. High scores on the scale indicate high psychological resilience.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Empowerment Program for Cancer Survivors	NCT05768984	Cancer Survivor...	Empowerment pro...	18 Years - 65 Years	Hacettepe University
Sweden Cancerome Analysis Network - Breast (SCAN-B) Coupled to Psychological Resilience	NCT03430492	Breast Cancer		18 Years -	Lund University
Pecha Kucha Method Effects on Posttraumatic Growth and Psychological Resilience	NCT05836077	Posttraumatic G... Psychological R... Breast Cancer P...	Education with ...	18 Years - 80 Years	Istanbul Sabahattin Zaim University
Empowerment Program for Cancer Survivors	NCT05768984	Cancer Survivor...	Empowerment pro...	18 Years - 65 Years	Hacettepe University

Spots Global Cancer Trial Database for psychological resilience