Neoplasms

Skin and Connective Tissue Diseases

All Conditions

Digestive System Diseases

Breast Neoplasms

Gastrointestinal Neoplasms

Digestive System Neoplasms

Gastrointestinal Diseases

Antineoplastic Agents

All Drugs and Chemicals

Capecitabine

This is a mixed-methodology pilot study of patients currently taking oral chemotherapy for breast or gastrointestinal cancer. The quantitative portion of the study consists of self-report questionnaires assessing adherence, beliefs about medications, side effect experience, self-efficacy, and satisfaction with patient education; the qualitative portion is an interview guided by two open-ended questions.

Interviews will be conducted with the first 10 participants who agree to be interviewed (or until data saturation is reached). Self-report questionnaires assessing adherence, beliefs about medications, side effect experience, self-efficacy, and satisfaction with patient education; the qualitative portion is an interview guided by two open-ended questions. Data will be collected approximately 2 weeks - 6 months (2 - 24 weeks) after being prescribed capecitabine.

questionnaire and interview

Pamela Ginex, EdD, RN, OCN

The purpose of this study is to identify what makes it easier and what makes it harder to take oral chemotherapy.

Patient Factors Impacting Adherence to Oral Chemotherapy

A Pilot Study to Identify Patient Factors Impacting Adherence to Oral Chemotherapy

Participation in the study entails completion of five short questionnaires related to the medication adherence (Medication Adherence Questionnaire), beliefs about medication (Beliefs about Medications Questionnaire), side effect experience (Frequency, Intensity, and Burden of Side Effects Rating), self-efficacy (Self-efficacy for Appropriate Medication Use) and satisfaction with medication information (Satisfaction with Information about Medicines Scale) as well as a demographic and treatment data sheet.

Memorial Sloan Kettering Cancer Center

Symptoms and General Pathology

Death

Questionnaire completed by the parents Interview with the parents and the psychologist (University Rennes 2)

Questionnaire and interview

Guillaume Robert

Cancer is the second cause of over-one-year-old children mortality after accident. Survival rate is more than 70%, but in some cases, curative treatments are not sufficient and palliative support is implemented for those children in end of life.

Pediatric guidelines about the place of end-of-life care are varied. On European scale, home is recommended (IMPaCCT study, 2007). In France, the 2008-2012 palliative care development program recommended home or initial hospital care unit. This program also supports implementation of mobile team rather than specific hospital units.

In Brittany, a pattern of regional palliative care resource team has been implemented since 2005. In oncology, further to the guidelines, end-of-life place of care is often discussed several times for each case. Sometimes occur a lot of returns between home and hospital, psychological difficulties, and difficulties to offer adapted care conditions. Finally, less than 30% of children in palliative care decease at home.

The primary objective is to identify main determinants of the place of palliative care in pediatric oncology.

The secondary objective is to clarify the factors of change comparing to the initial planned place.

Intervention :

Questionnaire completed by the parents Interview with the parents and the psychologist (University Rennes 2)

Number of subjects is : Parents of 68 to 93 children who died from cancer after a palliative phase, that means 136 to 186 parents.

Expected results and perspectives :

Using both quantitative and qualitative methods, expected results are the followings:

* Identification of the objective and subjective factors, which influenced the decision of the place of care.
* Determination of the factors of change comparing to the initial planned place.

Once identified, main factors could be the ones to pay attention to in order to help for initial decision, better anticipation of change of place and better guidance of palliative care organization wherever, at home or in hospital.

Results would be new information for research on palliative care for children but also for adults.

Finally, this work is part of an improving approach of palliative care, related to the development of open-care hospital networks. We can expect some public health impacts with new arguments to help for complementary recommendations.

Eligibility criteria :

Inclusion criteria are :

Parents of a deceased child

* From cancer, after palliative phase
* Age of death under 18 years old.
* Death occurred in Brittany
* Death between 2005 and 2010

Exclusion criterium is :

Parents of child who deceased after 2010 (respecting a bereavement delay)

Outcomes measures :

Primary study endpoint : Consideration or not by parents that they and/or their child had the choice of the end-of-life place of care.

Secondary study endpoints :

* objective factors : grade, occupational categories, marital status of parents, siblings, home conditions, access to the hospital, meeting with a professional of palliative care network, helpful general practitioner, volunteers, psychological support but also unexpected symptoms, needed nursing care which can explain a return from home to hospital for instance.
* subjective factors such as family or religious values, needs of intimacy, communication, support, sense of security, anxiety, fear, doubts about the next events.

Determinants of End-of-life Place of Care for Children Suffering From Cancer.

DELI-DEVI : Determinants of End-of-life Place of Care for Children Suffering From Cancer.

Consideration or not by parents that they and/or their child had the choice of the end-of-life place of care.

Objective factors : grade, occupational categories, marital status of parents, siblings, home conditions, access to the hospital, meeting with a professional of palliative care network, helpful general practitioner, volunteers, psychological support but also unexpected symptoms, needed nursing care which can explain a return from home to hospital for instance

Subjective factors such as family or religious values, needs of intimacy, communication, support, sense of security, anxiety, fear, doubts about the next events.

University of Rennes 2

Rennes University Hospital

Behaviors and Mental Disorders

Quality of Life

Cancer patients will answer questionnaires and will be interviewed by a pshychologist to assess their spirituality and quality of life toward their disease

Urielle DESALBRES

The general aim of research is to identify and analyze the impact and role of spirituality (as a search for meaning and understanding of the meaning of existence) in the experience of cancer. For this purpose, the main objective of this study is to measure the "existential" component in the trajectory of the disease. It is a question of observing its potential contribution to the improvement of the quality of life of the patients and to define if this variable can be translated into a strategy of adjustment for the patients. This research has a double interest: (a) clinical interest in better managing patients' needs; (B) an interest in research in the field of health by combining a measure of spirituality with other psycho-social variables.

The project is a prospective non-randomized mono-centric study by questionnaire and research interview. It is a study that seeks to identify the role of spirituality in the experience of illness (i.e. representations, adjustments, emotional distress) and as a determinant of the quality of life of subjects with cancer pathology.

The interviews will be conducted by a psychologist to qualitatively collect the elements of the lived experience of the disease in connection with the spiritual elements of the "quest for meaning" type.

The population covered by the project is in and out patients coming to the Department of Medical Oncology and Palliative Care at the CHU de la Timone.

The realization of this project will allow investigators to explore the specificity of the existential / spiritual dimensions of patients confronted with cancer, to assess the patients' needs for this type of approach within the hospital, to link the existential component / Spiritual with psycho-social variables

Spirituality, Experience of Disease and Quality of Life in Cancer Patients

Questionnaires(QLQC30) for patients with cancer.

Spirituality Index of Well-Being questionnaire

Assistance Publique Hopitaux De Marseille

Asthenia

The patient complete the questionnaire on the tablet to better know their social situation and any difficulties. Then, he will be interview during thirty minutes with a social worker and a nurse navigator. At the end of this intervention we will be offered to the patient monitoring and appropriate resources to its situation.

Franck Chauvin, PhD-MD

The main objective of the study is to validate a methodology with Psychometric tool to measure levels of patients social fragility.

This tool will be dematerialized on a tablet. The answers will be then processed by a decision support algorithm, which automatically send an alert to detection of social fragility of the patient to the nurse navigators.

Screening for Social Weaknesses and Coordination Course of Cancer Patients

Screening for Social Weaknesses and Coordination Course of Cancer Patients: A New Approach by an Expert System IT

Outcomes are content validity by expert judges method, appearance validity through a consensus, construct validity through exploratory factor analysis, discriminant validity in relation to the social fragility through univariate analysis, internal validity through factor analysis

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Patient Factors Impacting Adherence to Oral Chemotherapy	NCT01487343	Breast Cancer Gastrointestina...	questionnaire a...	21 Years -	Memorial Sloan Kettering Cancer Center
Determinants of End-of-life Place of Care for Children Suffering From Cancer.	NCT02060578	Cancer	Questionnaire a...	18 Years -	Rennes University Hospital
Spirituality, Experience of Disease and Quality of Life in Cancer Patients	NCT03245983	Psychology and ...	Questionnaire a...	18 Years - 85 Years	Assistance Publique Hopitaux De Marseille
Screening for Social Weaknesses and Coordination Course of Cancer Patients	NCT02369783	Cancer	Questionnaire a...	18 Years -	Institut de Cancérologie de la Loire

Spots Global Cancer Trial Database for questionnaire and interview