Mouth and Tooth Diseases

Skin and Connective Tissue Diseases

All Conditions

Neoplasms

Symptoms and General Pathology

Rare Diseases

Lichen Planus, Oral

Lichen Planus

Leukoplakia

Leukoplakia, Oral

Erythroplasia

Lichenoid Eruptions

Exanthema

Skin Diseases

Skin Diseases, Papulosquamous

Mouth Diseases

Stomatognathic Diseases

Precancerous Conditions

Pathological Conditions, Anatomical

Mouth Neoplasms

Head and Neck Neoplasms

Erythroplakia

Oral Leukoplakia

Oral Cancer

all dental hygienists members in the trade union for dental hygienists

A web-based questionnaire will be send by the trade union for dental hygienists

questionnaire survey

Karin Gunnars Hellgren

Dental health professionals have a responsibility to perform routine intra- and extraoral inspection on their patients for detecting abnormalities. As dental hygienists (DH) and dentist (D) often see their patients on a regular basis, they have the opportunity to provide this screening, and at an early stage detect abnormalities.

In Sweden, education and training in intraoral inspection of the oral mucosa is a part of the curriculum in dental hygienists education, so there is an expectation that the dental hygienist routinely perform tactile and visual intraoral inspections in practice. However, DH are not trained in extra oral inspection and are not allowed to diagnose an oral mucosal lesion, but are trained to identify abnormalities and determine whether the patient needs referral to a dentist. It is also to expect that the DH are capable to identify risk behaviors, such as alcohol and smoking, and recommend, and offer smoking cessation or refer the patient to a certified profession for smoking cessation.

In 2007, The World Health Assembly (WHA) adopted a resolution to prevent oral cancer. The resolution urged the member states to ensure that measures against oral cancer was integrated into a national cancer control program by engaging and train dental personnel in screening, early diagnosis and treatment. Oral cancer is a severe oral health issue as it is potentially fatal and is the 5-6 most common tumor with approximately 275,000 cases for oral and 130,300 cases for pharyngeal cancers, excluding nasopharynx, globally. In Sweden,1000 new cases yearly is discovered and it is increasing. The explanation is an aging population and an increase in tonsil and tongue cancers caused by HPV, especially in younger subjects. Tumors caused by tobacco and alcohol are constant \[7-9\]. Despite the decreasing prevalence of smoking and certain smoking-associated cancers, an increased incidence of tonsillar cancer has been seen in both Finland and Sweden. High risk HPV (hrHPV) oral cancer is also increasing. The 5 year survival of oral cancer in Sweden is 55 % and only 3-4% in advanced cases. The etiology is hrHPV, exposure to tobacco and alcohol in 65% \[13\] and poor dental status. All are lifestyle factors so there are many opportunities for prevention and intervention. In 2016, 352 individuals in Sweden died in oral cancer compared with 135 individuals who died of cervical cancer. Leukoplakia (LP), erythroplakia (EP) and oral lichen planus (OLP) are the dominating oral premalignant entities. The diagnosis are clinical and often by biopsies. The nonhomogeneous have a risk of malignant transformation of 3.6-8.9% in Scandinavia. OLP is a chronic inflammatory lesion where the atrophic and erosive types have a risk of cancer development of 0.5-2%.

The potential for prevention is high, as the risk factors are well known. The Clinical examination discloses any potentially malignant lesions. Being aware of the increasing number of head, neck, and oral tumors we need to highlight the importance of inspection of the oral mucosa.

Intra and Extra Oral Inspection of Oral Mucosa

Dental Hygienists and Oral Mucosal Inspection - Extent, Knowledge and Perceived Barriers

A 27-item survey instrument using Likert-type and open-ended questions, constructed by dental hygienists and used in Canada, College of dental hygienists Nova Scotia, Canada is used. Frequency and comprehensiveness of intra- and extra-oral inspection is investigated and participants can answer always, usually, sometimes, rarely or never.

From a drop down meny participants get seven alternative barriers; • Someone else in my office performs the exam \[if selected drop down menu options appear: dentist, dental assistant, do not know, other

* Lack of knowledge and/or skills to perform the exam
* Lack of time
* Concern about patient compliance
* Concern over remuneration for services
* Not sure if it is within the dental hygiene scope of practice
* Other

Dalarna County Council, Sweden

Principal Investigator

Breast Neoplasms

Breast Diseases

We will conduct a questionnaire survey of outpatients.

Earlier diagnosis of breast cancer in women and the use of systemic adjuvant therapy have increased the likelihood of long term, disease free survival.women who remain free of breast cancer seem to have levels of functioning and quality of life that are comparable to those of the general female population.It will be assessed the psychology status of women with breast cancer using a clinical interview,

It conducts a questionnaire survey of 300 patients. The questionnaires used are: Psychological Pain Thermometer DT, Hospital Anxiety and Depression Scale HADS, Quality of Life Scale for Breast Cancer Patients FACT-B, Social Support Rating Scale SSRS. Caregivers should fill in the following scales: Psychological Pain Thermometer DT, Hospital Anxiety and Depression Scale HADS, Caregiver Burden Assessment Scale ZBI. Inclusion criteria: 1,female patients with early breast cancer after surgery; 2,no previous mental and psychological abnormalities; 3,Postoperative and prepare to accept adjuvant chemotherapy ; 4,Patient's know her/his illness .

To explore:

1. Psychological status and dynamic changes of patients and caregivers during adjuvant chemotherapy after breast cancer surgery in China.
2. The influence of psychological status of Chinese breast cancer patients on adverse reactions during adjuvant chemotherapy.
3. Gene susceptibility to psychological abnormalities during adjuvant chemotherapy for breast cancer in China.

The Psychology of Chinese Breast Cancer Patients

DT uses to identify sources of distress. It uses a 0 (no distress) to 10 (extreme distress).

HADS was divided into an anxiety subscale and a depression subscale. Each item is scored from 0 (not at all) to 3 (very much) such that total scores on each sub-scale may range from 0-21.

Social support was measured by SSRS. The total score ranges from 12 to 66 points, and higher score indicates higher social support for patients.

The FACT-B is a 37-item instrument evaluating QoL issues. The domain scores for physical, social/family and functional well-being range from 0 to 28, the emotional domain scores from 0 to 24 points, the breast cancer- specific subscale domain scores from 0 to 40.

ZBI Is developed as 29-item self-report scale aimed to assess the subjective burden experienced by an caregiver.

Ma Fei，MD

Deputy Director of Medical Oncology

Digestive System Diseases

Carcinoma

Carcinoma, Hepatocellular

Liver Neoplasms

Gastrointestinal Neoplasms

Digestive System Neoplasms

Gastrointestinal Diseases

Liver Diseases

All patients received lifestyle questionnaire, physical performance, and imaging evaluation before treatment.

By tracking the short-term and long-term results of HCC patients treated with systemic therapies,the difference of microbiota between responded patients and non-responded patients was analyzed, and the correlation between gut and oral microbiota and short-term and long-term results was explored, so as to improve people's awareness of microbiota and pay attention to its prevention and treatment.

The investigators consecutively admit patients the questionnaire and collect the fecal. And by tracking the short-term and long-term outcomes of HCC patients treated with systemic therapies,the difference of gut microbiota between responded patients and non-responded patients is analyzed, and the correlation between gut and oral microbiota and short-term and long-term results is explored.Adverse events (AE) are recorded using the National Cancer Institute's Common Terminology Criteria for Adverse Events (version 4.0).Tumor response is mainly evaluated by experienced hepatologists using radiological method within 4-12 weeks after treatments according to the RECIST 1.1 and Modified Response Evaluation Criteria in Solid Tumors (mRECIST).Overall survival (OS) and Progression-free survival (PFS) are recorded.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Intra and Extra Oral Inspection of Oral Mucosa	NCT04079491	Oral Lichen Pla... Oral Leukoplaki... Erythroplakia	questionnaire s...	-	Dalarna County Council, Sweden
The Psychology of Chinese Breast Cancer Patients	NCT05055375	Breast Cancer	questionnaire s...	18 Years - 75 Years	Cancer Institute and Hospital, Chinese Academy of Medical Sciences
Relationship Between Microbiota and Prognosis of Hepatocellular Carcinoma(HCC) After Systemic Treatments	NCT05443217	Liver Cancer Microbiota Adverse Event Prognosis Efficacy	questionnaire s...	18 Years - 80 Years	First Affiliated Hospital of Wenzhou Medical University
The Psychology of Chinese Breast Cancer Patients	NCT05055375	Breast Cancer	questionnaire s...	18 Years - 75 Years	Cancer Institute and Hospital, Chinese Academy of Medical Sciences

Spots Global Cancer Trial Database for questionnaire survey