Neoplasms

Symptoms and General Pathology

All Conditions

Nervous System Diseases

Musculoskeletal Diseases

Neoplasm Metastasis

Recurrence

Spinal Cord Neoplasms

Spinal Neoplasms

Neoplastic Processes

Central Nervous System Neoplasms

Nervous System Neoplasms

Spinal Cord Diseases

Central Nervous System Diseases

Patients undergo posterior spinal tumor resection on day 0.

Patients undergo anterior and posterior tumor resection on day 0.

therapeutic conventional surgery

Undergo anterior and posterior spinal tumor resection

quality-of-life assessment

Rahul Jandial, MD

This randomized clinical trial studies minimally invasive surgery in treating patients with spinal tumors. Posterior spinal tumor resection and anterior and posterior spinal tumor resection are less invasive types of surgery for spinal tumors and may have fewer side effects and improve recovery

PRIMARY OBJECTIVES:

I. Length of operation (operating room \[OR\] time). II. Estimated blood loss (EBL). III. Complication rate. IV. Neurological preservation.

SECONDARY OBJECTIVES:

I. Motor strength and sensory level (neurological outcome). II. Bladder and bowel function. III. Post-operative pain. IV. Hospital length of stay (recovery time). V. Arthrodesis.

OUTLINE: Patients are randomized to 1 of 2 treatment arms.

ARM I: Patients undergo posterior spinal tumor resection on day 0.

ARM II: Patients undergo anterior and posterior spinal tumor resection on day 0.

After completion of study treatment, patients are followed up for 6 months.

Minimally Invasive Surgery in Treating Patients With Spinal Tumors

Comparison of Minimally Invasive Approaches of Spine Tumor Surgery

Will be comparing means with the Wilcoxon test.

This is an assessment of sensory and motor functions based upon the ASIA Impairment Scale

Plain x-ray films and CT scans are used to determine the success of arthrodesis (spinal fusion in this case) which is the artificial induction of joint ossification between two bones via surgery. This is done to relieve intractable pain in a joint which cannot be managed by pain medication.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Minimally Invasive Surgery in Treating Patients With Spinal Tumors	NCT01308489	Adult Spinal Co... Recurrent Adult... Spinal Bone Met... Spinal Cord Met...	therapeutic con... therapeutic con... quality-of-life...	18 Years -	City of Hope Medical Center
Minimally Invasive Surgery in Treating Patients With Spinal Tumors	NCT01308489	Adult Spinal Co... Recurrent Adult... Spinal Bone Met... Spinal Cord Met...	therapeutic con... therapeutic con... quality-of-life...	18 Years -	City of Hope Medical Center

Spots Global Cancer Trial Database for recurrent adult spinal cord neoplasm