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Pancrelipase

Pancreatin

To evaluate the safety and efficacy of irreversible electroporation (IRE) for refractory neoplasms in liver and pancreas, the investigators used preoperative and postoperative US/CEUS/CT/MRI to assess lesions, and laboratory tests including the tumor markers to evaluate the general condition of patients. Intraoperative US/CEUS/CT would be applied to monitor ablation lesions.

Effectivity and safety of irreversible electroporation for refractory neoplasms in liver and pancreas

Electroporation

Tian'an Jiang, Phd

Guo Tian, Master

The pupose of this study is to evaluate the safety and efficacy of irreversible electroporation (IRE) for refractory neoplasms in liver and pancreas, the investigators used preoperative and postoperative US/CEUS/CT/MRI to assess lesions, and laboratory tests including the tumor markers to evaluate the general condition of patients. Intraoperative US/CEUS/CT would be applied to monitor ablation lesions.

Effectivity and Safety of Irreversible Electroporation for Refractory Neoplasms in Liver and Pancreas

First Affiliated Hospital of Zhejiang University

The investigators used percutaneously US-guided laser ablation for patients with small hepatocellular carcinoma (single or multiple nodules of less than 3 cm in diameter), Child-Pugh A/B, PLT ≥ 50\*10E9/L and PT ≤ 20s. Then the investigators estimated the safety and efficacy of this treatment through follow-up of US/CEUS/CT/MRI and the tumor markers every three months.

US-guided laser ablation for refractory neoplasms

The purpose of this study is to evaluate the safety and efficacy of ultrasonography (US) -guided laser ablation liver, kidney, pancreas, lung and retroperitoneal tumors, the investigators used preoperative and postoperative US/CEUS/CT/MRI to assess lesions, and laboratory tests including the tumor markers to evaluate the general condition of patients. Intraoperative US/CEUS/CT would be applied to monitor ablation lesions.

Effectivity and Safety of Ultrasound-guided Percutaneously Laser Ablation for Refractory Neoplasms

EUS-guided laser ablation for refractory neoplasms

The purpose of this study is to evaluate the safety and efficacy of endoscopic ultrasonography (EUS) guided laser ablation liver, pancreas, and retroperitoneal tumors, the investigators used preoperative and postoperative US/CEUS/CT/MRI to assess lesions, and laboratory tests including the tumor markers to evaluate the general condition of patients. Intraoperative US/CEUS/CT would be applied to monitor ablation lesions.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Effectivity and Safety of Irreversible Electroporation for Refractory Neoplasms in Liver and Pancreas	NCT02822066	Refractory Neop...	Electroporation	18 Years - 100 Years	First Affiliated Hospital of Zhejiang University
Effectivity and Safety of Ultrasound-guided Percutaneously Laser Ablation for Refractory Neoplasms	NCT02822053	Refractory Neop...	US-guided laser...	18 Years - 100 Years	First Affiliated Hospital of Zhejiang University
Effectivity and Safety of Endoscopic Ultrasonography-guided Laser Ablation for Refractory Neoplasms	NCT02816944	Refractory Neop...	EUS-guided lase...	18 Years - 100 Years	First Affiliated Hospital of Zhejiang University
Effectivity and Safety of Endoscopic Ultrasonography-guided Laser Ablation for Refractory Neoplasms	NCT02816944	Refractory Neop...	EUS-guided lase...	18 Years - 100 Years	First Affiliated Hospital of Zhejiang University

Spots Global Cancer Trial Database for refractory neoplasms