Neoplasms

Digestive System Diseases

All Conditions

Rare Diseases

Esophageal Neoplasms

Gastrointestinal Neoplasms

Digestive System Neoplasms

Head and Neck Neoplasms

Gastrointestinal Diseases

Esophageal Diseases

Esophageal Cancer

Central Nervous System Depressants

All Drugs and Chemicals

Analgesics

Adjuvants, Anesthesia

Antiemetics

Gastrointestinal Agents

Anesthetics

Ropivacaine

Anesthetics, Local

Sufentanil

Granisetron

Dsuvia

Dezocine

Patients were given continuous RISS plane block in addition to patient controlled intravenous analgesia.

Patients were given single RISS plane block in addition to patient controlled intravenous analgesia.

Patients were given patient controlled intravenous analgesia.

Before the operation,the patient was placed in the left lateral position.The catheter（soft tip epidural catheter 20-gauge-100 cm） was placed at the rhomboid-intercostal plane under ultrasound guidance at the T5-T6 level, followed by ultrasound-guided catheter placed in the anterior serrated muscle plane at the T7-9 level。

Catheterization

Before the operation,40milliliters of 0.3% ropivacaine was injected into the rhomboid-intercostal fascia plane and anterior serrated muscle plane respectively under the guidance of ultrasound.

Single nerve block

After surgery,local anesthetics were injected continuously through catheters.Local anesthetic formula:Ropivacaine 300mg + normal saline, prepared into 150milliliters liquid, background dose 2milliliters/h.

Continuous nerve block

After surgery, the patient was given controlled intravenous analgesia. Analgesic pump drug formula:Sufentanil 50ug+ Dezocine 20mg+ Granisetron 10mg+150milliliters saline, continuous dose of 2milliliters/h intravenous pump, single injection dose of 2milliliters, locking time of 20 min

PCIA

Luo fuchao, MD

The objective is to investigate the safety and effectiveness of rhomboid intercostal and subserratum plane (RISS) block for postoperative analgesia after minimally invasive McKeown esophagectomy (MIE-McKeown).

Rhomboid intercostal and subserratum plane block (RISS) is a nerve block technique in which local anesthetics are injected into the rhomboid-intercostal muscle planes and the serratus anterius-intercostal muscle planes, and the intercostal nerve is blocked by diffusion of local anesthetics. It is confirmed that RISS can provide analgesia not only in the front half of the chest, but also in the upper abdomen. However, the efficacy of RISS in minimally invasive surgery for esophageal cancer has not been proven. The investigators placed catheters on the RISS plane and continuously injected local anesthetics to investigate whether RISS is effective and safe in minimally invasive esophageal cancer surgery.

Rhomboid Intercostal and Subserratum Plane Block for Minimally Invasive Esophagectomy

Clinical Study of Rhomboid Intercostal and Subserratum Plane Block for Postoperative Analgesia in Minimally Invasive Esophagectomy

patient will be asked to rate their pain level at rest and cough respectively using visual analogue scale（VAS）.(0 being no pain, 10 being worst pain imaginable)

The mean arterial pressure (MAP)on the monitor at different times was recorded.

The Heart rate (HR)on the monitor at different times was recorded.

The occurrence of nausea /vomiting was recorded

The occurrence of hypotension was recorded

The occurrence of respiratory depression was recorded

The occurrence of urinary retention was recorded

patient will be asked to rate their Satisfaction with analgesia using verbal rating scales (VRS) .Scores from 1 to 5 represent very dissatisfied, not satisfied, basically satisfied, relatively satisfied, and very satisfied with the analgesic effect, respectively.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Rhomboid Intercostal and Subserratum Plane Block for Minimally Invasive Esophagectomy	NCT06092944	Esophagus Cance...	Catheterization Single nerve bl... Continuous nerv... PCIA	18 Years - 75 Years	Fuling Central Hospital of Chongqing City
Rhomboid Intercostal and Subserratum Plane Block for Minimally Invasive Esophagectomy	NCT06092944	Esophagus Cance...	Catheterization Single nerve bl... Continuous nerv... PCIA	18 Years - 75 Years	Fuling Central Hospital of Chongqing City

Spots Global Cancer Trial Database for rhomboid intercostal and subserratum plane block