Nervous System Diseases

Heart and Blood Diseases

All Conditions

Behaviors and Mental Disorders

Wounds and Injuries

Neoplasms

Stroke

Cognitive Dysfunction

Brain Injuries

Brain Injuries, Traumatic

Brain Neoplasms

Cerebrovascular Disorders

Brain Diseases

Central Nervous System Diseases

Vascular Diseases

Craniocerebral Trauma

Trauma, Nervous System

Cognition Disorders

Neurocognitive Disorders

Mental Disorders

Psychotic Disorders

Central Nervous System Neoplasms

Nervous System Neoplasms

Specific inclusion criteria for this participants' group are:

- unilateral right hemispheric lesion after an ischemic or hemorrhagic stroke.

There are no specific exclusion criteria for this participants' group (see general exclusion criteria).

Participants will undergo a detailed neuropsychological assessment as detailed in the study's detailed description and outcome measures sections.

Specific inclusion criteria for this participants' group are:

- unilateral left hemispheric lesion after an ischemic or hemorrhagic stroke.

There are no specific exclusion criteria for this participants' group (see general exclusion criteria).

Participants will undergo a detailed neuropsychological assessment as detailed in the study's detailed description and outcome measures sections.

Specific inclusion criteria for this participants' group are:

* presence of a traumatic brain injury episode
* absence of previous neurological and psychiatric conditions.

There are no specific exclusion criteria for this participants' group (see general exclusion criteria).

Participants will undergo a detailed neuropsychological assessment as detailed in the study's detailed description and outcome measures sections.

Specific inclusion criteria for this participants' group are:

- unilateral right hemispheric brain tumor.

There are no specific exclusion criteria for this participants' group (see general exclusion criteria).

Participants will undergo a detailed neuropsychological assessment as detailed in the study's detailed description and outcome measures sections.

Specific inclusion criteria for this participants' group are:

- unilateral left hemispheric brain tumor.

There are no specific exclusion criteria for this participants' group (see general exclusion criteria).

Participants will undergo a detailed neuropsychological assessment as detailed in the study's detailed description and outcome measures sections.

Specific inclusion criteria for this participants' group are:

* MCI diagnosis according to Petersen et al., 2006 criteria
* absence of previous neurological and psychiatric conditions.

There are no specific exclusion criteria for this participants' group (see general exclusion criteria).

Participants will undergo a detailed neuropsychological assessment as detailed in the study's detailed description and outcome measures sections.

Specific inclusion criteria for this participants' group are:

- absence of neurological and psychiatric conditions.

There are no specific exclusion criteria for this participants' group (see general exclusion criteria).

Participants will undergo a detailed neuropsychological assessment as detailed in the study's detailed description and outcome measures sections.

* APACS assessing various aspects of pragmatic communication abilities;
* SET assessing cognitive and emotional theory of mind;
* COAST assessing functional communication impairments in daily activities and their impact on the quality of life after the illness onset;
* PWB assessing the individual's perceived quality of life and psychological well-being;
* other neuropsychological assessment tools depending on the participant's pathology and routinely used in the clinical practice within the Institution.

Neuropsychological assessment

Giorgio Arcara

Pragmatics of language refers to the set of abilities that allow one to use and interpret language according to context and, in general, to communicate effectively. Disorders in the pragmatics of language are prevalent in various clinical populations. They are a cause of social withdrawal and worse quality of life, both for patients directly affected and for their family members. Despite this, this type of disorder is rarely considered in neuropsychological assessment and rehabilitation.

This study's objective is to characterize pragmatic deficits in various neurological populations, allowing for the most accurate diagnosis possible and leading to the planning of personalized and effective Rehabilitation Plans.

To delineate the pragmatic deficit profile for each pathology group, eligible participants will undergo a neuropsychological assessment, subdivided into as many sessions as per the participant's availability and tolerance.

Assessment tools will include:

* APACS (A test for the Assessment of Pragmatic Abilities and Cognitive Substrates; Arcara and Bambini, 2016)
* SET (Story-based Empathy Task, Dodich et al., 2015)
* COAST (Communication Outcome After Stroke, Bambini et al., 2016)
* PWB (Psychological Well-Being scales, Sirigatti et al., 2009)
* other neuropsychological assessment tools depending on the participant's pathology and routinely used in the clinical practice within the Institution.

Resulting test scores will be statistically analyze to provide pragmatic and cognitive profiles for each pathology.

Neural and Cognitive Correlates of Pragmatic Abilities

Neural and Cognitive Correlates of Pragmatic Communication Abilities

results at ASsessemnt of Pragmatics Abilities and Cognitive Substrates (APACS) test

Results at Story Empathy Test (SET) score

Results at Communication Outcome After Stroke (COAST)

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Neural and Cognitive Correlates of Pragmatic Abilities	NCT06297044	Right Hemispher... Left Hemispheri... Traumatic Brain... Right Hemispher... Left Hemispheri... Mild Cognitive ... Healthy	Neuropsychologi...	18 Years -	IRCCS San Camillo, Venezia, Italy
Neural and Cognitive Correlates of Pragmatic Abilities	NCT06297044	Right Hemispher... Left Hemispheri... Traumatic Brain... Right Hemispher... Left Hemispheri... Mild Cognitive ... Healthy	Neuropsychologi...	18 Years -	IRCCS San Camillo, Venezia, Italy

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