Antineoplastic Agents

All Drugs and Chemicals

Trastuzumab

Antineoplastic Agents, Immunological

Participants will be assigned sequentially to escalating doses of runimotamab up to the maximum tolerated dose (MTD).

Participants will receive runimotamab based on the MTD or maximum allowed dose (MAD) identified during dose escalation.

Runimotamab will be administered via IV infusion until disease progression, intolerable toxicity, or any other discontinuation criteria are met.

Runimotamab

Trastuzumab will be administered via IV infusion

Participants will receive IV tocilizumab if needed

Tocilizumab

Clinical Trials

This study will evaluate the safety, tolerability, and pharmacokinetics of Runimotamab administered intravenously as a single agent and in combination with Trastuzumab in participants with locally advanced or metastatic Human Epidermal Growth Factor Receptor 2 (HER2)-expressing cancers.

A Study of Runimotamab in Participants With Locally Advanced or Metastatic HER2-Expressing Cancers

A Phase Ia/Ib, Open-Label, Dose-Escalation Study of the Safety and Pharmacokinetics of Runimotamab Administered Intravenously as a Single Agent and in Combination With Trastuzumab in Patients With Locally Advanced or Metastatic HER2-Expressing Cancers

Spots Global Cancer Trial Database for runimotamab

Every month we try and update this database with for runimotamab cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for runimotamab

Every month we try and update this database with for runimotamab cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for runimotamab cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.