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sacral canal cyst microscopic tamponade treatment; resting state functional magnetic resonance imaging (rfMRI)

gabapentin + tramadol tablets; resting state functional magnetic resonance imaging (rfMRI)

resting state functional magnetic resonance imaging (rfMRI)

sacral canal cyst microscopic tamponade treatment

sacral canal cyst microscopic tamponade

dose range：gabapentin 400-1200mg tid, tramadol 100-200mg bid

gabapentin + tramadol

First time:2 days before Surgery or Drug use; Second time:3 months after Surgery or Drug use; Third time:1 year after Surgery or Drug use

jiangkai lin, PhD

weihua chu, PhD

There are very few data and analysis in the literature regarding the symptomatic sacral perineurial cysts. Most studies are case reports or small retrospective sample, which rarely more than 20 cases. There is no an consensus on the choice of treatment (medicine conservative treatment and surgical treatment) for symptomatic sacral perineurial cysts.Our aim, therefore, is to compare the efficacy of medicine conservative treatment and surgical treatment for symptomatic sacral perineurial cysts by a randomized controlled trial. Meanwhile, resting-state functional magnetic resonance imaging is used to detect the changes at pain related brain areas, which will be develop an objective method to evaluate the clinical curative effect of the two treatment options.

Treatment of the Symptomatic Sacral Perineurial Cysts

A Randomized Controlled Trial to Compare the Efficacy of Medicine Conservative Treatment and Surgical Treatment for Symptomatic Sacral Perineurial Cysts (Tarlov Cysts) and the Applied Value of Resting State Functional Magnetic Resonance Imaging (rfMRI).

Southwest Hospital, China

Vice chief of Neurosurgery Department

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Treatment of the Symptomatic Sacral Perineurial Cysts	NCT02595190	Pain	sacral canal cy... gabapentin + tr... resting state f...	18 Years - 60 Years	Southwest Hospital, China
Treatment of the Symptomatic Sacral Perineurial Cysts	NCT02595190	Pain	sacral canal cy... gabapentin + tr... resting state f...	18 Years - 60 Years	Southwest Hospital, China

Spots Global Cancer Trial Database for sacral perineurial cysts(tarlov cysts)