Spots Global Cancer Trial Database for Treatment of the Symptomatic Sacral Perineurial Cysts

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Trial Identification

Brief Title: Treatment of the Symptomatic Sacral Perineurial Cysts

Official Title: A Randomized Controlled Trial to Compare the Efficacy of Medicine Conservative Treatment and Surgical Treatment for Symptomatic Sacral Perineurial Cysts (Tarlov Cysts) and the Applied Value of Resting State Functional Magnetic Resonance Imaging (rfMRI).

Study ID: NCT02595190

Conditions

Pain

Interventions

sacral canal cyst microscopic tamponade

gabapentin + tramadol

resting state functional magnetic resonance imaging (rfMRI)

Study Description

Brief Summary: There are very few data and analysis in the literature regarding the symptomatic sacral perineurial cysts. Most studies are case reports or small retrospective sample, which rarely more than 20 cases. There is no an consensus on the choice of treatment (medicine conservative treatment and surgical treatment) for symptomatic sacral perineurial cysts.Our aim, therefore, is to compare the efficacy of medicine conservative treatment and surgical treatment for symptomatic sacral perineurial cysts by a randomized controlled trial. Meanwhile, resting-state functional magnetic resonance imaging is used to detect the changes at pain related brain areas, which will be develop an objective method to evaluate the clinical curative effect of the two treatment options.

Detailed Description: