Neoplasms

Urinary Tract, Sexual Organs, and Pregnancy Conditions

All Conditions

Uterine Cervical Neoplasms

Uterine Neoplasms

Genital Neoplasms, Female

Urogenital Neoplasms

Uterine Cervical Diseases

Uterine Diseases

Genital Diseases, Female

Genital Diseases

Urogenital Diseases

Female Urogenital Diseases

Pregnancy Complications

Female Urogenital Diseases and Pregnancy Complications

Ye Chen, doctor

Zheng Hu, doctor

Our study is conducted to recruit cervical cancer screening patients to evaluate the application value of using high-throughput sequencing technology to detect HPV in menstrual blood for cervical cancer screening.

Our study aims to recruit 10,000 cervical cancer screening patients from the outpatient department of Zhongnan Hospital of Wuhan University from September 1, 2023 to March 31, 2028. The procedures were conducted as below: (1) Conduct cervical cancer screening (TCT+cobas-HPV) for all the participants. (2) Collect sanitary napkins from participants during their first menstrual period after cervical HPV testing. (3) Detect HPV using high-throughput sequencing technology in the menstrual blood (MB) from sanitary napkins. (4) Colposcopy referral (biopsy if necessary) for patients with abnormal screening results. (5) Compare the concordance between MB-HPV and cobas-HPV.

The study aims to collect sanitary napkins for menstrual blood which contains cells.

Cervical Cancer Screening With NGS-HPV Technology Based on Menstrual Blood

There is no plan to make individual participant data (IPD) available to other researchers.

Exploring the concordance between MB-HPV and cobas-HPV

Zhongnan Hospital

Digestive System Diseases

Colorectal Neoplasms

Intestinal Neoplasms

Gastrointestinal Neoplasms

Digestive System Neoplasms

Gastrointestinal Diseases

Colonic Diseases

Intestinal Diseases

Rectal Diseases

Behavioral: small media intervention using video, flip chart, and pamphlets and a tailored interactive multimedia intervention

small media intervention using video, flip chart, and pamphlets and a tailored interactive multimedia intervention

Maria E. Fernandez, PhD

During this first year, the researchers have worked toward identifying factors influencing initiation of colorectal cancer screening among Hispanic men and women aged 50 and older and developing an intervention plan using Intervention Mapping, a framework for systematic health promotion program planning, implementation, and evaluation. The researchers are also currently in the preliminary stages of developing two promotora (lay health worker)-delivered interventions: a small media intervention (video, flip chart, pamphlets) and a tailored interactive multimedia intervention, prior to the actual collection of data. Thus, although 733 subjects have been approved by the Committee for the Protection of Human Subjects to be enrolled in this study in the future, no subjects have been enrolled at this time. Consequently, there have been no adverse events, and since the risks associated with participating in this study are negligible, the researchers do not anticipate any adverse events in the future. No modifications have been made to the research since the last review, other than that the researchers are currently reassessing the need to conduct preliminary qualitative research as proposed in the original protocol.

Use and Decision-making About Colorectal Cancer Screening Among Hispanic Men and Women

Trial of Interventions to Increase Utilization of Colorectal Cancer Screening and Promote Informed Decision Making About Colorectal Cancer Screening Among Hispanic Men and Women

Centers for Disease Control and Prevention

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Cervical Cancer Screening With NGS-HPV Technology Based on Menstrual Blood	NCT06082765	Cervical Cancer		20 Years - 55 Years	Zhongnan Hospital
Cervical Cancer Screening With NGS-HPV Technology Based on Menstrual Blood	NCT06082765	Cervical Cancer		20 Years - 55 Years	Zhongnan Hospital
Use and Decision-making About Colorectal Cancer Screening Among Hispanic Men and Women	NCT00136227	Colorectal Canc...	small media int...	50 Years -	Centers for Disease Control and Prevention

Spots Global Cancer Trial Database for screening,

Every month we try and update this database with for screening, cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for screening,

Every month we try and update this database with for screening, cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for screening, cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.