Wounds and Injuries

All Conditions

Neoplasms

Digestive System Diseases

Surgical Wound

Colorectal Neoplasms

Intestinal Neoplasms

Gastrointestinal Neoplasms

Digestive System Neoplasms

Gastrointestinal Diseases

Colonic Diseases

Intestinal Diseases

Rectal Diseases

Anti-Inflammatory Agents

All Drugs and Chemicals

Antirheumatic Agents

Anti-Inflammatory Agents, Non-Steroidal

Preoperative:

preadmission information, education, counseling, optimization ( breathing training), shortening fasting time and carbohydrate load

Intraoperative:

The intravenous fluid therapy is restricted. All patients undergo single incision plus one port laparoscopic surgery(SILS plus one).

A suitable warming device (such as forced-air heating blankets) and warmed intravenous fluids are been adopted routinely to keep body temperature

Postoperative:

multimodal analgesia (surgical site infiltration, a nonsteroidal anti-inflammatory drug, epidural analgesia) early oral intake and move. nasogastric tubes should not be used routinely. Nasogastric tubes inserted during surgery are been removed before reversal of an aesthesia.

SILS plus one port surgery and enhanced recovery after surgery protocol both are methods taking the minimally invasive benefits for the patients including faster recovery, reduced postoperative pain and shorter hospital stay.

Single incision plus one port laparoscopic surgery

Wang Yanan, M.D

Wang Yannan, M.D

Conventional laparoscopic surgery (CLS) for colorectal cancer has been demonstrated to be safe and feasible and present minimally invasive benefits including faster recovery, reduced postoperative pain and shorter hospital stay, also acquiring comparable oncologic outcomes with open surgery. To achieve further minimally invasive outcomes, SILS plus one port surgery was attempted by some surgeons. Preliminary results showed that SILS+1 could achieve better minimally invasive benefits than CLS while preserving oncologic feasibility.

Till now, ERAS has been practiced in colorectal cancer surgery for approximately 20 years. Studies have proven that ERAS is safe and significantly improved the recovery course of patients during perioperative period, meanwhile, the expense could be greatly reduced.

Based on ERAS studies protocols and SILS+1 trials, investigators tried to combine SILS+1 with ERAS, hopefully to provide patients with more safe, economic, feasible and rapid surgery and perioperative strategies.

Single Incision Plus One Port Laparoscopic Surgery Assistant Enhanced Recovery After Surgery on Colorectal Cancer

Effect of Single Incision Plus One Port Laparoscopic Surgery Assistant Enhanced Recovery After Surgery on Colorectal Cancer : A Single Arm Trial

The percentage of patients who met discharge criteria in the fourth day after surgery

The patient's expenses from surgery to discharge are recorded in RMB "yuan"

Postoperative pain is recorded using the visual analog scale (VAS) pain score tool on postoperative day . On a scale of 1 to 10, the higher the score, the greater the pain.

The first Time to early mobilization(hour), flatus(hour), liquid diet(hour), soft diet(hour), removal of the Nasogastric tubes(hour) , removal of the peritoneal drainage(hour) are used to assess the postoperative recovery

It includes the number of white blood cells and lymphocytes,CRP, IL-6

It is defined as if the patients complete every ERAS measure or not. We can defined it "yes " or "not".

Study site, subject preparation, trial procedures, and medical monitoring refer to the 6MWT guidelines issued by the American thoracic society in 2002.

It can be defined as the number of patients readmitted within 30 days because of postoperative complications.

Morbidity and mortality rates are defined as postoperative complications graded according to Clavien-Dindo within 30 days.

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Single Incision Plus One Port Laparoscopic Surgery Assistant Enhanced Recovery After Surgery on Colorectal Cancer	NCT04268290	Colorectal Canc...	Single incision...	18 Years - 75 Years	Nanfang Hospital, Southern Medical University
Single Incision Plus One Port Laparoscopic Surgery Assistant Enhanced Recovery After Surgery on Colorectal Cancer	NCT04268290	Colorectal Canc...	Single incision...	18 Years - 75 Years	Nanfang Hospital, Southern Medical University

Spots Global Cancer Trial Database for single incision plus one port laparoscopic surgery