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Vaccines

Subjects are randomized to receive one of five messages on one of the four themes about HPV vaccination.

Subjects are randomized to receive one of five messages about electronic cigarettes.

Messages educate parents with facts about HPV vaccination.

Social Media Message about HPV and HPV vaccine

Messages educate parents with facts about electronic cigarettes. This is an attention control group without outcomes obtained.

Social media message about risk of electronic cigarettes.

Ardis L Olson, MD

This project involves a social media campaign to increase parent's knowledge and acceptance of the HPV (human papillomavirus) vaccine. The current vaccine protects against nine types of HPV, including seven that are known to cause cancer. The Centers for Disease Control and Prevention (CDC) estimates that the current HPV vaccine could prevent 90% of cancer cases caused by HPV, including cases of cervical cancer, oropharyngeal (mouth and throat) cancer, anal cancer, and others. About 150 and 104 cases of HPV-associated cancers are diagnosed each year in New Hampshire and Vermont, respectively-many of which could be prevented through vaccination. Currently, only 49.8% of New Hampshire adolescents and 44.3% of Vermont adolescents were not up-to-date for HPV vaccination as of 2016. This social media campaign is testing a set of campaign messages with parents locally and nationally to see which messages are most effective in improving their knowledge and acceptance of the vaccine. A study survey link will monitor the number of people reached and will measure parental intention to get their children vaccinated against HPV.

Participants are not aware of which arm of social messaging they are receiving and whether they are receiving the control message or not

HPV Message Testing and Social Media Campaign

Change in Attitudes about HPV vaccine: Pre to post test comparison of summated 9 items measured on a 7-point scale of HPV vaccine attitudes. Scores range from a minimum of 9 to a maximum of 63. Higher scores indicated more positive attitudes toward HPV vaccination. Change was calculated from two time points, the later time point(\<1 hour post messaging intervention) minus value at baseline.

A sub-group of parents of 9-14 year old children who had not been vaccinated were asked on pre- and post-test: How likely is it that she/he will receive the HPV vaccine in the next 12 months? Responses range form 1 (very likely) to 5 (not very likely).

HPV vaccination behavioral intent change scores were calculated by subtracting pre- and post- test values. It is a negative-value scale, in which smaller values indicate more positive attitude change after exposure to the viewed message.

National Cancer Institute (NCI)

Norris Cotton Cancer Center

Dartmouth-Hitchcock Medical Center

Physician, Professor of Pediatrics

Subjects are randomized to receive one of five messages on one of the four themes about HPV vaccination.

Social Media Message about HPV and HPV vaccine: Messages educate parents with facts about HPV vaccination.

HPV Messaging

Subjects are randomized to receive one of five messages about electronic cigarettes.

Social media message about risk of electronic cigarettes.: Messages educate parents with facts about electronic cigarettes. This is an attention control group without outcomes obtained.

Control Message

834 Subjects are randomized to receive one of five messages on one of the five themes about HPV vaccination.(165-167/group)

Social Media Message about HPV and HPV vaccine: Messages educate parents with facts about HPV vaccination.

164 Subjects are randomized to receive one of five messages about electronic cigarettes.

Social media message about risk of electronic cigarettes.: Messages educate parents with facts about electronic cigarettes. This is an attention control group without outcomes obtained.

Total

Years of age of parent as reported by study participant who identifies them as a parent on survey.

Age, Continuous

Sex: Female, Male

Race and Ethnicity were not collected from any participant.

Race and Ethnicity Not Collected

Prior knowledge of HPV

This is a single question with the results reported as the answer from 1 to 5 on perceived effective of vaccine in preventing the cancer. Lower scores show a higher perception of it being effective. The full title is used without abbreviation.

HPV Vaccine in prevents Cervical Cancer

5 point scale from strongly disagree to strongly agree.

This is a single question with the results reported as the answer from 1 to 5 on perceived effective of vaccine in preventing the cancer. Lower scores show a higher perception of it being effective. The full title is used without abbreviation.

HPV Vaccine in prevents Throat Cancer

1,713 participants initially recruited but 631 ineligible because no child leaving 1,043 eligible. Of eligibles 998 completed baseline survey.

Dr. Ardis Olson

834 Subjects were randomized to receive one of 25 experimental messages about HPV vaccination

164 Subjects received a control message not about HPV vaccination.

Control Messaging

1 participant in the experimental group and 2 participants in the control group withdrew from the study and are not included in the analysis.

Change in Attitudes About HPV Vaccine

Change in mean scores for behavioral intent to vaccine: negative values: smaller values indicate more likely to vaccinate.

Subjects were randomized to receive one of 25 experimental messages about HPV vaccination.

Behavioral intention to vaccinate only asked of the 155 HPV messaginglgroup parents with children 9-14 years who had not vaccinated their children at time of this experiment

Subjects received a control message not about HPV vaccination.

Behavioral intention to vaccinate only asked of the 34 HPV controllgroup parents with children 9-14 years who had not vaccinated their children at time of this experiment

A sub-group of parents of 9-14 year old children who had not been vaccinated were asked on pre- and post-test: How likely is it that she/he will receive the HPV vaccine in the next 12 months? Responses range form 1 (very likely) to 5 (not very likely).

Behavioral Intention to Vaccinate Their Child With HPV Vaccine

834 Subjects were randomized to receive an experimental message about HPV vaccination.

Spots Global Cancer Trial Database for social media message about risk of electronic cigarettes.