Neoplasms

Skin and Connective Tissue Diseases

All Conditions

Breast Neoplasms

Breast Diseases

Skin Diseases

Odour sampling: Rub hands with Sorbstar® before and post-surgery

Odour sampling: Sleep over a night with a compress on the affected breast before and after surgery

Thermodesorption method coupled with full two-dimensional gas chromatography and mass spectrometry.

Sorbstar®

Analyzed by the dogs of Curie Institute at the training centers

Odour sampling

Roman ROUZIER, Phd

Isabelle FROMANTIN, Phd, IDE

To ascertain the possibilities to isolate the breast cancer olfactive signature.

Patient recruitment during the first surgery consultation in Curie Institute. Odor sampling (non-invasive) with an odor-sensing polymer (Sorbstar® polymer developed especially for the trace level analysis), on:

* The hands, before and after surgical excision of the tumor (friction of the hands)
* The diseased breast, before and after surgical excision of the tumor (via a compress positioned on the breast for 1 night)
* The tumor, during the surgical procedure (odor collection over a tumor sample).

Each patient will be her own witness, before and after surgical excision, in an attempt to isolate the chemical signature tracks of breast cancer. The samples after surgery will be made after healing and before implementation of a treatment (chemotherapy and / or radiotherapy).

Interventional, prospective, open, monocentric study with risks and minimal constraints

Isolation of Volatile Organic Compounds (VOCs) Related to the Olfactory Signature of Breast Cancer

Feasibility Study on the Possibility of Isolation of Volatile Organic Compounds (VOCs) Related to the Olfactory Signature of Breast Cancer

Isolation of volatile Organic Compounds to breast cancer by a sensitive technique with an odor-sensing polymer (Sorbstar®) on hands. Friction of the hands according to the protocol before and after surgical excision of the tumor. Sorbstar® analyses will be performed with a thermodesorption method coupled with full two-dimensional gas chromatography and mass spectrometry.

During the surgical procedure an odor-sensing polymer (Sorbstar®) over the tumor is placed. Sorbstar® analyzes will be performed with a thermodesorption method coupled with full two-dimensional gas chromatography and mass spectrometry.

Patients sleep over a night with a compress positioned on the affected breast before and after surgery. The compress will be analyzed by the dogs of Curie Institut (results cancer/not cancer).

Institut Curie

Odour sampling : rub hands with Sorbstars® before and post-surgery

Odour sampling :sleep over a night with a compress on the affected breast before and after surgery

Thermodesorption method coupled with full two-dimensional gas chromatography and mass spectrometry

Analysed by the dogs of Curie Institute at the training centers

Dog Detection

Fromantin Isabelle, PhD

To ascertain the possibilities to isolate the breast cancer olfactive signature

Patient recruitment during the first surgery consultation in Curie Institute.

Odor sampling (non-invasive) with an odor-sensing polymer (Sorbstar® polymer developed especially for the trace level analysis), on:

* The hands, before and after surgical excision of the tumor (friction of the hands)
* The diseased breast, before and after surgical excision of the tumor (via a compress positioned on the breast for 1 night)
* The tumor, during the surgical procedure (odor collection over a tumor sample).

Each patient will be her own witness, before and after surgical excision, in an attempt to isolate the chemical signature tracks of breast cancer. The samples after surgery will be made after healing and before implementation of a treatment (chemotherapy and / or radiotherapy).

Experimental, interventional, prospective, open, monocentric study with risks and minimal constraints

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization
Isolation of Volatile Organic Compounds (VOCs) Related to the Olfactory Signature of Breast Cancer	NCT03703557	Breast Cancer Surgery	Sorbstar® Odour sampling	18 Years -	Institut Curie
Isolation of Volatile Organic Compounds (VOCs) Related to the Olfactory Signature of Breast Cancer	NCT03703557	Breast Cancer Surgery	Sorbstar® Odour sampling	18 Years -	Institut Curie
Isolation of Volatile Organic Compounds (VOCs) Related to the Olfactory Signature of Breast Cancer.	NCT04541537	Breast Cancer Surgery	Sorbstar® Dog Detection	18 Years -	Institut Curie

Spots Global Cancer Trial Database for sorbstar®

Every month we try and update this database with for sorbstar® cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Spots Global Cancer Trial Database for sorbstar®

Every month we try and update this database with for sorbstar® cancer trials from around the world to help patients and their families find trials that might be right for them. We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.

Every month we try and update this database with for sorbstar® cancer trials from around the world to help patients and their families find trials that might be right for them.
We offer this 100% free of charge and do not endorse any of the trials listed here, we hope it helps you or a loved one.