Neoplasms

Skin and Connective Tissue Diseases

All Conditions

Symptoms and General Pathology

Musculoskeletal Diseases

Nervous System Diseases

Ganglion Cysts

Pain

Shoulder Pain

Synovial Cyst

Cysts

Arthralgia

Joint Diseases

Neurologic Manifestations

Mucinoses

Connective Tissue Diseases

Anti-Arrhythmia Agents

Channel Blockers

Central Nervous System Depressants

All Drugs and Chemicals

Lidocaine

Anesthetics

Anesthetics, Local

Sodium Channel Blockers

Diuretics, Potassium Sparing

Patients who are undergoing a thoracotomy will be informed that they may develop moderate to severe postoperative ISP and may have the option to receive an SPG block. The SPG block will be performed every three minutes for 20 minutes, 0.1mL of the 4% lidocaine will be administered through. After 20 minutes and various intervals thereafter the patient will be asked to rate their shoulder pain.

Sphenopalatine Ganglion (SPG) Block

lidocaine

Gilbert Grant, MD

The purpose of this pilot study is to evaluate the utility of sphenopalatine ganglion (SPG) block to manage ipsilateral shoulder pain (ISP) after thoracotomy. This will be an open label preliminary pilot study to determine if SPG block has potential utility to manage ISP in post-thoracotomy patients. The primary outcome variable will be reduction of shoulder pain.

This is an open label preliminary pilot study which will evaluate the utility of sphenopalatine ganglion (SPG) block to manage ipsilateral shoulder pain (ISP). It will determine if SPG block has potential utility to manage ISP in post-thoracotomy patients One hundred (100) patients will initially be consented in this study. Patients have to develop ISP and have a pain VAS \>= 5. The study is seeking ten (10) eligible participants.

Patients will be followed after the SPG block(s), and the duration of pain relief will be monitored by serial assessments of the VAS. This assessment will occur for the initial SPG block and for all follow-up blocks, if performed. The follow-up assessments will only involve having the patient rate the ISP using a verbal VAS; This will take less than a minute of patients time. In addition, all patients will have PRN access to standard systemic analgesics as routinely ordered by the surgical service Safety assessments will be performed on all subjects. Blood pressure, heart rate and respiratory rate will be obtained every 15 minutes after each SPG block for 90 minutes. Dr. Grant will monitor the subjects for 90 minutes after each SPG block.

Sphenopalatine Ganglion Block to Treat Shoulder Pain After Thoracotomy

Sphenopalatine Ganglion Block to Treat Shoulder Pain After Thoracotomy- An Open Label Pilot Study

Patients will be followed after the SPG block(s) and the duration of pain relief will be monitored by serial assessments of the VAS. This assessment will occur for the initial SPG block and for all follow-up blocks, if performed.

NYU Langone Health

Heart and Blood Diseases

Stroke

Headache

Ischemic Stroke

Ischemia

Cerebrovascular Disorders

Brain Diseases

Central Nervous System Diseases

Vascular Diseases

The investigational treatment is 1.5 mL of aqueous 2% lidocaine.

The placebo arm is 1.5mL of aqueous of saline.

The investigational treatment is 2 mL of aqueous 2% lidocaine.

Liquid Lidocaine

The active placebo comparator will be provided to participant.

Placebo

Ka-Ho Wong

Seniha Ozudogru, MD

Adam H de Havenon, MD, MSCI

Ka-Ho Wong, MBA

Adam H de Havenon, MD

Determine the effects of sphenopalatine ganglion (SPG) block in post-stroke headache.

The purpose of this study is to determine if sphenopalatine ganglion (SPG) block is a safe and effective treatment for acute post-stroke headache. Current literature lacks randomized controlled studies regarding the efficacy of different treatment modalities for acute post-stroke headache; additionally, there are no evidence-based guidelines for the treatment of acute post-stroke headache. Sphenopalatine ganglion block is a non-invasive procedure where an anesthetic agent is injected into the nares, reaching the SPG to relieve pain and autonomic features. This treatment has been effective in a variety of headache types but to our knowledge has not been studied in acute post-stroke headache.

Sphenopalatine Ganglion Block for the Treatment of Post-Stroke Headache

Evaluate the efficacy of Lidocaine delivered to SPG, based on the use of rescue medication and number of headache in headache diary

The quantitative scale ranges from 0 to 10, with 0 meaning "no headache at all" and 10 meaning "the worst possible headache."

Bitter taste, nose bleeding, throat discomfort

Study title	NCT ID	Conditions	Interventions	Eligibility	Organization	Link
Sphenopalatine Ganglion Block to Treat Shoulder Pain After Thoracotomy	NCT02733393	Ipsilateral Sho...	Sphenopalatine ... lidocaine	18 Years -	NYU Langone Health
Sphenopalatine Ganglion Block for the Treatment of Post-Stroke Headache	NCT05365880	Headache Stroke Ischemic Stroke	Liquid Lidocain... Placebo	18 Years -	University of Utah

Spots Global Cancer Trial Database for sphenopalatine ganglion (spg) block